| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mycobacterium Infections | D009164 | 7 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Carbon Tetrachloride Poisoning | D002252 | 12 associated lipids |
| Femoral Neck Fractures | D005265 | 3 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ho YC et al. | Human hepatic beta-glucuronidase: an enzyme kinetic study. | 1985 | Enzyme | pmid:3987656 |
| Ohnhaus EE et al. | Liver blood flow and enzyme induction in man. | 1985 | Hepatogastroenterology | pmid:4007764 |
| Idéo G et al. | Urinary D-glucaric acid excretion in the Seveso area, polluted by tetrachloro-dibenzo-p-dioxin (TCDD): five years of experience. | 1985 | Environ. Health Perspect. | pmid:4029098 |
| Couvaris M et al. | Bioavailability of hetacillin in rats after liver enzyme induction by various inducers with or without protein binding properties. | 1985 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:4029217 |
| Kinoshita H et al. | The relationship between hepatic microsomal biphenyl 2-hydroxylase, 4-hydroxylase and urinary glucaric acid excretion in the rat. | 1985 Jul-Sep | Eur J Drug Metab Pharmacokinet | pmid:4085526 |
| Pitt D and Mosley MJ | Enzymes of gluconate metabolism and glycolysis in Penicillium notatum. | 1985 | Antonie Van Leeuwenhoek | pmid:4091540 |
| Steinberg KK et al. | Assessment of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure using a modified D-glucaric acid assay. | 1985 | J Toxicol Environ Health | pmid:4093993 |
| Hunter J et al. | Urinary D-glucaric-acid excretion as a test for hepatic enzyme induction in man. | 1971 | Lancet | pmid:4100904 |
| Aarts EM | D-glucaric-acid excretion as a test for hepatic enzyme induction. | 1971 | Lancet | pmid:4102545 |
| Hunter J et al. | D-glucaric-acid excretion as a test for hepatic enzyme induction. | 1971 | Lancet | pmid:4103690 |
| Edwards OM et al. | Changes in cortisol metabolism following rifampicin therapy. | 1974 | Lancet | pmid:4140269 |
| Sotaniemi EA et al. | Glucaric acid as an indicator of use of enzyme-inducing drugs. | 1974 | Clin. Pharmacol. Ther. | pmid:4150733 |
| Latham AN | D-Glucaric acid as an index of hepatic enzyme induction by anticonvulsant drugs in man. | 1974 | J. Pharm. Pharmacol. | pmid:4151390 |
| Smith SE and Rawlins MD | Prediction of drug oxidation rates in man: lack of correlation with serum gamma-glutamyl transpeptidase and urinary excretion of D-glucaric acid and 6 beta-hydroxycortisol. | 1974 | Eur. J. Clin. Pharmacol. | pmid:4153008 |
| Davidson DC et al. | Assessment of plasma glutamyl transpeptidase activity and urinary D-glucaric acid excretion as indices of enzyme induction. | 1974 | Clin Sci Mol Med | pmid:4154014 |
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| Ohnhaus EE et al. | The effect of enzyme induction on diazepam metabolism in man. | 1979 | Br J Clin Pharmacol | pmid:42427 |
| Freundt KJ | Production of endogenous D-glucaric acid and oxidative N-demethylation of amidopyrine in man: lack of correlation. | 1979 | Int J Clin Pharmacol Biopharm | pmid:429081 |
| Park BK et al. | [Modification of the action of drugs by inhibition of their metabolism]. | 1979 | Recenti Prog Med | pmid:42953 |
| Notten WR and Henderson PT | Effect of disulfiram on the urinary D-glucaric acid excretion and activity of some enzymes involved in drug metabolism in guinea-pig. | 1973 | Arch Int Pharmacodyn Ther | pmid:4357069 |
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| Masaki H | [Metabolic pathway of D-glucaric acid synthesis from D-glucuronolactone in the skin. II. Identification of the intermediates in D-glucuronolactone D-glucaric acid metabolism]. | 1972 | Nihon Hifuka Gakkai Zasshi | pmid:4540858 |
| Nasaki H | [Metabolic pathway of D-glucaric acid synthesis from D-glucuronolactone in the skin. 1. D-glucaric acid and D-glucuronolactone dehydrogenase activities in the human skin--feedback mechanism of beta-glucuronidase]. | 1972 | Nihon Hifuka Gakkai Zasshi | pmid:4540880 |
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| Sartor P and Cohere G | [Iron saccharate capture by rat uterus epithelium. Experimental study with respect to hormonal status]. | 1973 | C. R. Seances Soc. Biol. Fil. | pmid:4794498 |
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| Maxwell JD et al. | Folate deficiency after anticonvulsant drugs: an effect of hepatic enzyme induction? | 1972 | Br Med J | pmid:5008482 |
| Matsui M et al. | Studies on the glucaric acid pathway in the metabolism of D-glucuronic acid in mammals. IV. Fluorometric method for the determination of D-glucaric acid in serum. | 1972 | Chem. Pharm. Bull. | pmid:5065229 |
| Buchanan N et al. | Antipyrine pharmacokinetics and D-glucaric excretion in kwashiorkor. | 1979 | Am. J. Clin. Nutr. | pmid:506967 |
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| Masuda H and Heirwegh KP | Different inhibition rates of beta-glucuronidase fractions in human gallbladder bile by glucaro-1, 4-lactone. | 1979 | Fukuoka Igaku Zasshi | pmid:511089 |
| Hunter J et al. | Altered calcium metabolism in epileptic children on anticonvulsants. | 1971 | Br Med J | pmid:5115570 |
| Kennedy AC et al. | Hypercalcaemia in rheumatoid arthritis: investigation of its causes and implications. | 1979 | Ann. Rheum. Dis. | pmid:518139 |
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