| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Hypercalcemia | D006934 | 13 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mycobacterium Infections | D009164 | 7 associated lipids |
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Carbon Tetrachloride Poisoning | D002252 | 12 associated lipids |
| Femoral Neck Fractures | D005265 | 3 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sotaniemi EA et al. | Measurement of hepatic drug-metabolizing enxyme activity in man. Comparison of three different assays. | 1980 | Eur. J. Clin. Pharmacol. | pmid:6105079 |
| Berlin I et al. | [The effect of contraceptives on serum lipids, gamma glutamyl transpeptidase and D-glucaric acid elimination]. | 1980 | Orv Hetil | pmid:6110202 |
| de Wolff FA et al. | Valproate induces urinary D-glucaric acid excretion. | 1981 | Lancet | pmid:6111706 |
| Hajós P et al. | The effect of oral contraceptives on serum lipids gamma-glutamyl transpeptidase, and excretion of d-glucaric acid. | 1981 | Int J Clin Pharmacol Ther Toxicol | pmid:6112206 |
| Walter E et al. | Induction of drug metabolizing enzymes by sulfinpyrazone. | 1981 | Eur. J. Clin. Pharmacol. | pmid:6113147 |
| Park BK and Breckenridge AM | Clinical implications of enzyme induction and enzyme inhibition. | 1981 Jan-Feb | Clin Pharmacokinet | pmid:6113907 |
| Malaka-Zafiriu K et al. | Serum gamma-glutamyl transpeptidase, D-glucaric acid excretion and plasma half-life of antipyrine in newborns with severe jaundice of unknown etiology and due to glucose-6-phosphate dehydrogenase deficiency in Greece. | 1981 | Helv Paediatr Acta | pmid:6114077 |
| May G | Tetrachlorodibenzodioxin: a survey of subjects ten years after exposure. | 1982 | Br J Ind Med | pmid:6121580 |
| Tutor JC et al. | Serum copper concentration and hepatic enzyme induction during long-term therapy with anticonvulsants. | 1982 | Clin. Chem. | pmid:6122516 |
| de Wolff FA et al. | Serum concentrations and enzyme induction in epileptic children treated with phenytoin and valproate. | 1982 | Neuropediatrics | pmid:6123089 |
| Dolara P et al. | Variations of some parameters of enzyme induction in chemical workers. | 1982 | Ann Occup Hyg | pmid:6124202 |
| Jung K et al. | [D-glucaric acid excretion in kidney transplant patients as an indicator of microsomal enzyme capacity]. | 1982 | Z Urol Nephrol | pmid:6126971 |
| Park BK | Assessment of the drug metabolism capacity of the liver. | 1982 | Br J Clin Pharmacol | pmid:6128018 |
| Kawasaki H et al. | Effects of phenobarbital on unconjugated bilirubin clearance, gamma-glutamyltranspeptidase and urinary d-glucaric acid in patients with Gilbert's syndrome. | 1982 | Hepatogastroenterology | pmid:6130037 |
| Wright JH et al. | Hepatic enzyme induction patterns and phenothiazine side effects. | 1983 | Clin. Pharmacol. Ther. | pmid:6137306 |
| de Wolff FA et al. | The effects of valproic acid on liver function. | 1983 | Arch. Toxicol. Suppl. | pmid:6138013 |
| Peduto VA et al. | Stimulation of drug-metabolizing enzymes by nitrous oxide in the rat. | 1983 | Acta Anaesthesiol Scand | pmid:6141696 |
| Døssing M | Noninvasive assessment of microsomal enzyme activity in occupational medicine: present state of knowledge and future perspectives. | 1984 | Int Arch Occup Environ Health | pmid:6142865 |
| Perry W and Stamp TC | Urinary D-glucaric acid excretion during rifampicin/isoniazid and anticonvulsant enzyme induction. | 1984 | Clin. Pharmacol. Ther. | pmid:6143635 |
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| Carrella M et al. | An evaluation of urinary D-glucaric acid excretion during acute hepatitis in man. | 1978 | Am J Dig Dis | pmid:619622 |
| Walaszek Z et al. | Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumorigenesis by 2,5-di-O-acetyl-D-glucaro-1,4:6,3-dilactone, an in vivo beta-glucuronidase inhibitor. | 1984 | Carcinogenesis | pmid:6202433 |
| pmid:6209078 | ||||
| Martin JV | Lipid abnormalities in workers exposed to dioxin. | 1984 | Br J Ind Med | pmid:6232943 |
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| Walters DG et al. | Direct determination of D-[U-14C] glucaric acid in urine by ion-exchange high-performance liquid chromatography. | 1983 | J. Chromatogr. | pmid:6423654 |
| Fujita M et al. | Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation. | 1984 | Gan | pmid:6432619 |
| Perucca E et al. | A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. | 1984 | Br J Clin Pharmacol | pmid:6435654 |
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| Imamura K | Effects of intravenous administration of iron preparations on the metabolism of phosphorus. Comparative study on 3 iron preparations. | 1984 | Fukuoka Igaku Zasshi | pmid:6489911 |
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| Freundt KJ et al. | Concentrations of D-glucaric acid in human urine after repeated administration of pyrithioxine. | 1984 | Int J Clin Pharmacol Ther Toxicol | pmid:6526537 |
| Hrubisko M et al. | Drug resistance induction and cross-resistance studies with Pt-complexes. | 1984 | Neoplasma | pmid:6542968 |
| Wang CY and Hayashida S | Enhancement by phenothiazine and 2,5-di-O-acetyl-D-glucosaccharo-(1,4)(6,3)-dilactone of bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in rats. | 1984 | Cancer Lett. | pmid:6548659 |
| Stevens PM et al. | Urinary D-glucaric acid and oral contraceptives. | 1978 | Br J Clin Pharmacol | pmid:656297 |
| Oberhaensli RD et al. | Different actions of deferoxamine and iron on Ga-67 abscess detection in rats. | 1984 | J. Nucl. Med. | pmid:6587029 |
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| Dolara P et al. | Enzyme induction in humans exposed to styrene. | 1983 | Ann Occup Hyg | pmid:6614729 |
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