Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Li H and Wang SX | [Intravenous iron sucrose in maintenance dialysis patients with renal anemia: a clinical study]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:19567093 |
Jung K et al. | [D-glucaric acid excretion in kidney transplant patients as an indicator of microsomal enzyme capacity]. | 1982 | Z Urol Nephrol | pmid:6126971 |
Schröder O et al. | A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding. | 2004 | Z Gastroenterol | pmid:15314711 |
Giger M and Achermann R | [Iron substitution in outpatients in Switzerland: Increase of costs associated with intravenous administration]. | 2013 | Z Evid Fortbild Qual Gesundhwes | pmid:23916272 |
Kaizu T | [Non-dialyzable beta-glucuronidase inhibitor in guinea-pig urine. I. Purification (author's transl)]. | 1975 | Yakugaku Zasshi | pmid:1238533 |
Hasegawa K et al. | [Improvement of urinary d-glucaric acid assay and its application]. | 2008 | Yakugaku Zasshi | pmid:18176065 |
Warrander A and Waring RH | An improved method for gas chromatographic determination of urinary xylitol and glucuronic, glucaric gulonic and ascorbic acids, with their values in the rat, rabbit, guinea-pig and marmoset. | 1978 | Xenobiotica | pmid:102085 |
Mori M et al. | Urinary and biliary metabolites of mephentermine in male Wistar rats. | 1989 | Xenobiotica | pmid:2665325 |
Layiwola PJ et al. | Hydrolysis of the biliary glucuronic acid conjugate of phenol by the intestinal mucus/flora of goldfish (Carassius auratus). | 1983 | Xenobiotica | pmid:6858197 |
Lake BG et al. | The excretion of metabolites of the D-glucuronic acid pathway in human urine. Effect of phenobarbitone administration. | 1982 | Xenobiotica | pmid:7113260 |
Brunelle FM and Verbeeck RK | Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. | 1996 | Xenobiotica | pmid:8867997 |
Hong SK and Rankin GO | Biotransformation of 2-chloroaniline in the Fischer 344 rat: identification of urinary metabolites. | 1998 | Xenobiotica | pmid:9849645 |
Marselos M et al. | Responses of the D-glucuronic acid pathway in rat tissues to treatment with tetrachlorodibenzodioxin. | 1978 | Xenobiotica | pmid:685288 |
Muñoz M et al. | Intravenous iron in inflammatory bowel disease. | 2009 | World J. Gastroenterol. | pmid:19787830 |
Lutz W and Kralkowska E | [Laboratory diagnosis of subclinical forms of chemically-induced liver damage]. | 1986 | Wiad. Lek. | pmid:2873689 |
GarcÃa-Erce JA et al. | Efficacy of preoperative recombinant human erythropoietin administration for reducing transfusion requirements in patients undergoing surgery for hip fracture repair. An observational cohort study. | 2009 | Vox Sang. | pmid:19497085 |
Birgegård G et al. | High incidence of iron depletion and restless leg syndrome (RLS) in regular blood donors: intravenous iron sucrose substitution more effective than oral iron. | 2010 | Vox Sang. | pmid:20598107 |
Bespalov VG and Aleksandrov VA | [Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors]. | 2012 | Vopr Onkol | pmid:23607211 |
Düllmann J et al. | [Iron storage and metabolism in nacrophages and endothelial cells after intravenous administration of colloidal ferric saccharate in man]. | 1976 | Verh Anat Ges | pmid:1024396 |
Montano-Pedroso JC et al. | Postoperative intravenously administered iron sucrose versus postoperative orally administered iron to treat post-bariatric abdominoplasty anaemia (ISAPA): the study protocol for a randomised controlled trial. | 2016 | Trials | pmid:27068478 |