Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Barbieri C et al. | Performance of a Predictive Model for Long-Term Hemoglobin Response to Darbepoetin and Iron Administration in a Large Cohort of Hemodialysis Patients. | 2016 | PLoS ONE | pmid:26939055 |
pmid:26948581 | ||||
pmid:26956439 | ||||
pmid:27001529 | ||||
Han YM et al. | Comparison of the Efficacies of Parenteral Iron Sucrose and Oral Iron Sulfate for Anemic Patients with Inflammatory Bowel Disease in Korea. | 2016 | Gut Liver | pmid:27021505 |
pmid:27038710 | ||||
Gourley GR et al. | The effect of saccharolactone on rat intestinal absorption of bilirubin in the presence of human breast milk. | 1989 | Pediatr. Res. | pmid:2704588 |
Montano-Pedroso JC et al. | Postoperative intravenously administered iron sucrose versus postoperative orally administered iron to treat post-bariatric abdominoplasty anaemia (ISAPA): the study protocol for a randomised controlled trial. | 2016 | Trials | pmid:27068478 |
Pasquini R et al. | Urinary excretion of mutagens, thioethers and D-glucaric acid in workers exposed to bitumen fumes. | 1989 | Int Arch Occup Environ Health | pmid:2707871 |
Liddil JD et al. | Association of lysosomal activity with sensitivity and resistance to tumor necrosis factor in murine L929 cells. | 1989 | Cancer Res. | pmid:2713856 |
pmid:27141568 | ||||
pmid:27161817 | ||||
Zager RA et al. | Combined iron sucrose and protoporphyrin treatment protects against ischemic and toxin-mediated acute renal failure. | 2016 | Kidney Int. | pmid:27165818 |
Fell LH et al. | Impact of individual intravenous iron preparations on the differentiation of monocytes towards macrophages and dendritic cells. | 2016 | Nephrol. Dial. Transplant. | pmid:27190361 |
pmid:27197731 | ||||
pmid:27198564 | ||||
pmid:27218635 | ||||
pmid:27218636 | ||||
pmid:27236130 | ||||
pmid:27236131 | ||||
Faber F et al. | Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion. | 2016 | Nature | pmid:27309805 |
pmid:27312887 | ||||
pmid:27444324 | ||||
pmid:27522633 | ||||
Dwivedi C et al. | Effects of the experimental chemopreventative agent, glucarate, on intestinal carcinogenesis in rats. | 1989 | Carcinogenesis | pmid:2752528 |
pmid:27540710 | ||||
Gemici C et al. | Is there any role of intravenous iron for the treatment of anemia in cancer? | 2016 | BMC Cancer | pmid:27542823 |
Song D et al. | AMD-like retinopathy associated with intravenous iron. | 2016 | Exp. Eye Res. | pmid:27565570 |
pmid:27576956 | ||||
Garnham JC et al. | The effect of repeated administration of diftalone on enzyme induction. | 1978 | J. Pharm. Pharmacol. | pmid:27604 |
pmid:27713040 | ||||
Abou-Issa H et al. | Synergistic interaction between 13-cis-retinoic acid and glucarate: activity against rat mammary tumor induction and MCF-7 cells. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2783140 |
pmid:27852236 | ||||
pmid:27889746 | ||||
pmid:27915456 | ||||
Okada S et al. | Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats. | 1989 | Br. J. Cancer | pmid:2803947 |
Derman R et al. | A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia. | 2017 | Am. J. Hematol. | pmid:28052413 |
Siest G et al. | [Biological tests as indirect indicators of the activity of drug metabolizing enzymes. Use of glucaric acid and gamma-glutamyltransferase]. | 1977 | Ann. Biol. Clin. (Paris) | pmid:28055 |
pmid:28063734 | ||||
pmid:28215716 | ||||
pmid:28263291 | ||||
Deng Y et al. | Efficacy of Intravenous Iron Sucrose in Hemodialysis Patients with Restless Legs Syndrome (RLS): A Randomized, Placebo-Controlled Study. | 2017 | Med. Sci. Monit. | pmid:28285317 |
pmid:28372549 | ||||
pmid:28482869 | ||||
pmid:28562517 | ||||
pmid:28586635 | ||||
Adjarov D et al. | [Clinical significance of D-glucaric of D-glucaric acid determination in the urine of porphyria cutanea tarda patients]. | 1985 | Dermatol Monatsschr | pmid:2861119 |
pmid:28656646 | ||||
Heinemeyer G et al. | D-glucaric acid excretion in critical care patients--comparison with 6 beta-hydroxycortisol excretion and serum gamma-glutamyltranspeptidase activity and relation to multiple drug therapy. | 1986 | Br J Clin Pharmacol | pmid:2868749 |
Lutz W and Kralkowska E | [Laboratory diagnosis of subclinical forms of chemically-induced liver damage]. | 1986 | Wiad. Lek. | pmid:2873689 |