Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Silverberg D et al. | The use of androgens in anaemia resistant to erythropoietin and i.v. iron in patients with heart and renal failure. | 2004 | Nephrol. Dial. Transplant. | pmid:15031380 |
Hanausek M et al. | Detoxifying cancer causing agents to prevent cancer. | 2003 | Integr Cancer Ther | pmid:15035900 |
pmid:15050885 | ||||
Okada DR et al. | Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate. | 2004 | J. Nucl. Med. | pmid:15073263 |
Silverstein SB and Rodgers GM | Parenteral iron therapy options. | 2004 | Am. J. Hematol. | pmid:15114602 |
Koller WC et al. | Metabolism of glucurolactone to glucarate in Parkinson's disease. | 1992 | Neurology | pmid:1513472 |
Walaszek Z et al. | Mechanisms of lung cancer chemoprevention by D-glucarate. | 2004 | Chest | pmid:15136472 |
Hanausek M et al. | Modulation of biomarkers during chemoprevention of mouse lung tumorigenesis by D-glucarate. | 2004 | Chest | pmid:15136473 |
Scheiber-Mojdehkar B et al. | Non-transferrin-bound iron in the serum of hemodialysis patients who receive ferric saccharate: no correlation to peroxide generation. | 2004 | J. Am. Soc. Nephrol. | pmid:15153577 |
pmid:15160289 | ||||
pmid:15180183 | ||||
Oredipe OA et al. | Dietary glucarate-mediated inhibition of initiation of diethylnitrosamine-induced hepatocarcinogenesis. | 1992 | Toxicology | pmid:1519243 |
Liu Y et al. | New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells. | 2004 | J. Am. Chem. Soc. | pmid:15198572 |
Zager RA et al. | Parenteral iron nephrotoxicity: potential mechanisms and consequences. | 2004 | Kidney Int. | pmid:15200421 |
Sengoelge G et al. | Dose-dependent effect of parenteral iron therapy on bleomycin-detectable iron in immune apheresis patients. | 2004 | Kidney Int. | pmid:15200437 |
Liu Z et al. | 99mTc glucarate high-resolution imaging of drug sensitive and drug resistant human breast cancer xenografts in SCID mice. | 2004 | Nucl Med Commun | pmid:15208499 |
Pak KY et al. | Labeling and stability of radiolabeled antibody fragments by a direct 99mTc-labeling method. | 1992 | Int J Rad Appl Instrum B | pmid:1522021 |
Liu Z et al. | High-resolution imaging with (99m)Tc-glucarate for assessing myocardial injury in rat heart models exposed to different durations of ischemia with reperfusion. | 2004 | J. Nucl. Med. | pmid:15235074 |
Schröder O et al. | A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding. | 2004 | Z Gastroenterol | pmid:15314711 |
Tutor-Crespo MJ et al. | Possible induction of cholinesterase in epileptic patients treated with anticonvulsant drugs: relationship with lipoprotein levels. | 2004 | J Clin Pharmacol | pmid:15317825 |
Agarwal R | Transferrin saturation with intravenous irons: an in vitro study. | 2004 | Kidney Int. | pmid:15327409 |
Aronoff GR et al. | Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens. | 2004 | Kidney Int. | pmid:15327417 |
McMahon LP et al. | Effects of different dialysis membranes on serum concentrations of epoetin alfa, darbepoetin alfa, enoxaparin, and iron sucrose during dialysis. | 2004 | Am. J. Kidney Dis. | pmid:15332224 |
Schwenk MH and Blaustein DA | Rapid, high-dose intravenous iron sucrose therapy in 2 Jehovah's Witness patients with severe anemia, iron deficiency and chronic kidney disease. | 2004 | Clin. Nephrol. | pmid:15356968 |
Tiranathanagul K et al. | Oxidative stress from rapid versus slow intravenous iron replacement in haemodialysis patients. | 2004 | Nephrology (Carlton) | pmid:15363053 |
Leijn E et al. | Intravenous iron supplementation in children on hemodialysis. | 2004 May-Jun | J. Nephrol. | pmid:15365964 |
pmid:15371980 | ||||
pmid:15373973 | ||||
Dornyei A et al. | Vanadium(IV,V) complexes of D-saccharic and mucic acids in aqueous solution. | 2004 | Dalton Trans | pmid:15381996 |
Cuenca J et al. | Patients with pertrochanteric hip fracture may benefit from preoperative intravenous iron therapy: a pilot study. | 2004 | Transfusion | pmid:15383017 |
Mustajoki P et al. | Rapid normalization of antipyrine oxidation by heme in variegate porphyria. | 1992 | Clin. Pharmacol. Ther. | pmid:1544288 |
Wada S et al. | [Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer]. | 1992 | Hinyokika Kiyo | pmid:1546564 |
Agarwal R | On the nature of proteinuria with acute renal injury in patients with chronic kidney disease. | 2005 | Am. J. Physiol. Renal Physiol. | pmid:15467003 |
Borawski J et al. | Endothelial injury markers with high-dose intravenous iron therapy in renal failure. | 2004 | Clin. Appl. Thromb. Hemost. | pmid:15497030 |
Tutor-Crespo M et al. | Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs. | 2004 | J Pharm Pharm Sci | pmid:15576017 |
Kanamaru R and Wakui A | [Pharmacokinetic studies on fluorinated pyrimidine in cancer cell and tissue]. | 1992 | Gan To Kagaku Ryoho | pmid:1558391 |
Guz G et al. | Elevated cardiac troponin T in hemodialysis patients receiving more intravenous iron sucrose. | 2004 | Ren Fail | pmid:15600258 |
Ogi M et al. | [Comparison of intravenous ascorbic acid versus intravenous iron for functional iron deficiency in hemodialysis patients]. | 2004 | Nihon Jinzo Gakkai Shi | pmid:15645737 |
Sheashaa H et al. | Parenteral iron therapy in treatment of anemia in end-stage renal disease patients: a comparative study between iron saccharate and gluconate. | 2005 | Nephron Clin Pract | pmid:15692217 |
Liu Y and Reineke TM | Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery. | 2005 | J. Am. Chem. Soc. | pmid:15740138 |
Pecharki GD et al. | Effect of sucrose containing iron (II) on dental biofilm and enamel demineralization in situ. | 2005 Mar-Apr | Caries Res. | pmid:15741724 |
pmid:15745425 | ||||
pmid:15754533 | ||||
Cuenca J et al. | Role of parenteral iron in the management of anaemia in the elderly patient undergoing displaced subcapital hip fracture repair: preliminary data. | 2005 | Arch Orthop Trauma Surg | pmid:15789233 |
pmid:15795917 | ||||
pmid:15855210 | ||||
Schmittgen TD et al. | Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants. | 1992 | Cancer Chemother. Pharmacol. | pmid:1586977 |
Keven K et al. | Combination of intravenous iron sucrose and ascorbic acid in hemodialysis patients. | 2005 | Kidney Int. | pmid:15954940 |
pmid:16006090 | ||||
Agarwal R | Ironing out the mystery of nephrotoxicity of parenteral iron. | 2005 | J. Lab. Clin. Med. | pmid:16025083 |