Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sanai T et al. | Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats. | 2005 | J. Lab. Clin. Med. | pmid:16025088 |
| Bontchev RP and Moore RC | Crystal structure and aqueous solubility of ammonium D-glucarate. | 2005 | Carbohydr. Res. | pmid:16043161 |
| Wood DM et al. | Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child. | 2005 | Ther Drug Monit | pmid:16044093 |
| Macdougall IC and Roche A | Administration of intravenous iron sucrose as a 2-minute push to CKD patients: a prospective evaluation of 2,297 injections. | 2005 | Am. J. Kidney Dis. | pmid:16112047 |
| Perek N et al. | MRP-1 protein expression and glutathione content of in vitro tumor cell lines derived from human glioma carcinoma U-87-MG do not interact with 99mTc-glucarate uptake. | 2005 | Cancer Biother. Radiopharm. | pmid:16114987 |
| Zager RA | Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy. | 2005 | Kidney Int. | pmid:16164630 |
| Erichsen K et al. | Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. | 2005 | Scand. J. Gastroenterol. | pmid:16165718 |
| Strolin Benedetti M et al. | Induction of endogenous pathways by antiepileptics and clinical implications. | 2005 | Fundam Clin Pharmacol | pmid:16176329 |
| St Peter WL et al. | Trends in intravenous iron use among dialysis patients in the United States (1994-2002). | 2005 | Am. J. Kidney Dis. | pmid:16183420 |
| Ayotte P et al. | Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. | 2005 | Environ. Health Perspect. | pmid:16203240 |
| Ozdemir A et al. | Relationship between iron replacement and hepatic functions in hepatitis C virus-positive chronic haemodialysis patients. | 2005 | Nephrology (Carlton) | pmid:16221090 |
| Spiegel K et al. | Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. | 2005 | J. Appl. Physiol. | pmid:16227462 |
| Johnson G et al. | (99m)Tc-glucarate imaging for the early detection of infarct in partially reperfused canine myocardium. | 2006 | Eur. J. Nucl. Med. Mol. Imaging | pmid:16237571 |
| Aime S et al. | para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents. | 2005 | Org. Biomol. Chem. | pmid:16240012 |
| Glassman E | Oral iron therapy with ferrous fumarate and polysaccharide iron complex. | 1992 | ANNA J | pmid:1627011 |
| Georgopoulos D et al. | Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317]. | 2005 | Crit Care | pmid:16277712 |
| Schröder O et al. | Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease--a randomized, controlled, open-label, multicenter study. | 2005 | Am. J. Gastroenterol. | pmid:16279906 |
| Sengölge G et al. | Intravenous iron therapy: well-tolerated, yet not harmless. | 2005 | Eur. J. Clin. Invest. | pmid:16281958 |
| pmid:16286429 | ||||
| Tutor-Crespo MJ et al. | Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects. | 2005 | J. Pharmacol. Sci. | pmid:16314692 |
| Schaller G et al. | Intravenous iron increases labile serum iron but does not impair forearm blood flow reactivity in dialysis patients. | 2005 | Kidney Int. | pmid:16316358 |
| Van Wyck DB et al. | A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. | 2005 | Kidney Int. | pmid:16316362 |
| Laman CA et al. | Parenteral iron therapy: a single institution's experience over a 5-year period. | 2005 | J Natl Compr Canc Netw | pmid:16316614 |
| Anemia during pregnancy and in the postpartum: intravenous iron therapy revisited. | 2005 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:16360535 | |
| Govan AD and Scott JM | Intravenous iron in the treatment of anemia of pregnancy. 1949. | 2005 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:16360540 |
| Karkouti K et al. | Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia. | 2006 | Can J Anaesth | pmid:16371604 |
| Zheng H et al. | Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects. | 2006 | Kidney Int. | pmid:16395269 |
| pmid:16417257 | ||||
| Hoyle VR et al. | Studies on the biochemical effects of the aldose reductase inhibitor 2,7-difluorospirofluorene-9,5'-imidazolidine-2',4'-dione (Al 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy. | 1992 | Biochem. Pharmacol. | pmid:1642638 |
| Anbu AT et al. | Low incidence of adverse events following 90-minute and 3-minute infusions of intravenous iron sucrose in children on erythropoietin. | 2005 | Acta Paediatr. | pmid:16431410 |
| Cançado RD et al. | [Evaluation of the efficacy of intravenous iron III-hydroxide saccharate for treating adult patients with iron deficiency anemia]. | 2005 Nov-Dec | Rev Assoc Med Bras (1992) | pmid:16444338 |
| pmid:16504354 | ||||
| Brown SD et al. | A gold standard set of mechanistically diverse enzyme superfamilies. | 2006 | Genome Biol. | pmid:16507141 |
| pmid:16522172 | ||||
| Koutroubakis IE et al. | Effectiveness of darbepoetin-alfa in combination with intravenous iron sucrose in patients with inflammatory bowel disease and refractory anaemia: a pilot study. | 2006 | Eur J Gastroenterol Hepatol | pmid:16538115 |
| Agarwal R | Proinflammatory effects of iron sucrose in chronic kidney disease. | 2006 | Kidney Int. | pmid:16609688 |
| Muñoz M et al. | Role of parenteral iron in transfusion requirements after total hip replacement. A pilot study. | 2006 | Transfus Med | pmid:16623920 |
| Sudan C et al. | Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants. | 2006 | Planta | pmid:16652220 |
| Strack D et al. | Enzymic synthesis of caffeoylglucaric Acid from chlorogenic Acid and glucaric Acid by a protein preparation from tomato cotyledons. | 1987 | Plant Physiol. | pmid:16665274 |
| Guz G et al. | Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients. | 2006 | Nephrol. Dial. Transplant. | pmid:16762960 |
| Barton Pai A et al. | Non-transferrin-bound iron is associated with enhanced Staphylococcus aureus growth in hemodialysis patients receiving intravenous iron sucrose. | 2006 | Am. J. Nephrol. | pmid:16809897 |
| Coletta AP et al. | Clinical trials update from the European Society of Cardiology heart failure meeting: TNT subgroup analysis, darbepoetin alfa, FERRIC-HF and KW-3902. | 2006 | Eur. J. Heart Fail. | pmid:16887387 |
| Schiesser D et al. | Weekly low-dose treatment with intravenous iron sucrose maintains iron status and decreases epoetin requirement in iron-replete haemodialysis patients. | 2006 | Nephrol. Dial. Transplant. | pmid:16891647 |
| Kato M et al. | Tetranuclear copper(II) complexes bridged by alpha-D-glucose-1-phosphate and incorporation of sugar acids through the Cu4 core structural changes. | 2006 | Inorg Chem | pmid:16903719 |
| Carlini RG et al. | Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro. | 2006 | Nephrol. Dial. Transplant. | pmid:16957011 |
| Agarwal R | Is i.v. iron really superior in CKD patients not on dialysis? | 2006 | Kidney Int. | pmid:16957750 |
| Davey CL et al. | Esterification of select polyols with D-glucaric acid as model reactions for esterification of starch. | 2006 | Carbohydr. Res. | pmid:16973136 |
| Bolger AP et al. | Intravenous iron alone for the treatment of anemia in patients with chronic heart failure. | 2006 | J. Am. Coll. Cardiol. | pmid:16979010 |
| GarcÃa-Erce JA et al. | Perioperative intravenous iron preserves iron stores and may hasten the recovery from post-operative anaemia after knee replacement surgery. | 2006 | Transfus Med | pmid:16999756 |
| Bhandal N and Russell R | Intravenous versus oral iron therapy for postpartum anaemia. | 2006 | BJOG | pmid:17004982 |
| Yaoita H et al. | Localization of technetium-99m-glucarate in zones of acute cerebral injury. | 1991 | J. Nucl. Med. | pmid:1704054 |
| Eiselt J et al. | The effect of intravenous iron on oxidative stress in hemodialysis patients at various levels of vitamin C. | 2006 | Blood Purif. | pmid:17077626 |
| Sirken G et al. | Association of different intravenous iron preparations with risk of bacteremia in maintenance hemodialysis patients. | 2006 | Clin. Nephrol. | pmid:17140164 |
| Breborowicz A et al. | Iron sucrose induced morphological and functional changes in the rat kidney. | 2006 | Transl Res | pmid:17145571 |
| pmid:17198668 | ||||
| Watanabe S et al. | alpha-ketoglutaric semialdehyde dehydrogenase isozymes involved in metabolic pathways of D-glucarate, D-galactarate, and hydroxy-L-proline. Molecular and metabolic convergent evolution. | 2007 | J. Biol. Chem. | pmid:17202142 |
| Hörl WH | Iron therapy for renal anemia: how much needed, how much harmful? | 2007 | Pediatr. Nephrol. | pmid:17206511 |
| pmid:17226954 | ||||
| Kim YT et al. | Effect of intravenously administered iron sucrose on the prevention of anemia in the cervical cancer patients treated with concurrent chemoradiotherapy. | 2007 | Gynecol. Oncol. | pmid:17234260 |
| Olas B et al. | Protective effects of D-glucaro 1,4-lactone against oxidative/nitrative modifications of plasma proteins. | 2007 | Nutrition | pmid:17234507 |
| pmid:17264097 | ||||
| Izuel Rami M et al. | [Budget impact analysis of a blood saving program for urgent traumatological surgery]. | 2007 | Med Clin (Barc) | pmid:17266885 |
| Breymann C et al. | Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex. | 2007 | J Perinat Med | pmid:17302514 |
| Pai AB et al. | Comparison of oxidative stress markers after intravenous administration of iron dextran, sodium ferric gluconate, and iron sucrose in patients undergoing hemodialysis. | 2007 | Pharmacotherapy | pmid:17316146 |
| pmid:17322190 | ||||
| Marsillach J et al. | Administration of exogenous erythropoietin beta affects lipid peroxidation and serum paraoxonase-1 activity and concentration in predialysis patients with chronic renal disease and anaemia. | 2007 | Clin. Exp. Pharmacol. Physiol. | pmid:17324148 |
| George P et al. | Coronary artery vasospasm with iron sucrose. | 2007 | Nephrol. Dial. Transplant. | pmid:17327282 |
| Beck-da-Silva L et al. | Rationale and design of the IRON-HF study: a randomized trial to assess the effects of iron supplementation in heart failure patients with anemia. | 2007 | J. Card. Fail. | pmid:17338998 |
| Ranfaing E | [Treatments of the martial deficiencies: preparations available in France]. | 2006 | Nephrol. Ther. | pmid:17373280 |
| Sane R et al. | Safe administration of iron sucrose in a patient with a previous hypersensitivity reaction to ferric gluconate. | 2007 | Pharmacotherapy | pmid:17381390 |
| Iversen C et al. | The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cronobacter dublinensis sp. nov. and Cronobacter genomospecies 1. | 2007 | BMC Evol. Biol. | pmid:17439656 |
| Sav T et al. | Is there a difference between the allergic potencies of the iron sucrose and low molecular weight iron dextran? | 2007 | Ren Fail | pmid:17497463 |
| Breborowicz A et al. | Peritoneal effects of intravenous iron sucrose administration in rats. | 2007 | Transl Res | pmid:17543848 |
| pmid:17577885 | ||||
| Herzberg M et al. | Hepatic microsomal enzyme induction and its evaluation in a clinical laboratory. | 1977 | Isr. J. Med. Sci. | pmid:17578 |
| Auerbach M and Rodgers GM | Intravenous iron. | 2007 | N. Engl. J. Med. | pmid:17611217 |
| Agarwal R et al. | Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease. | 2007 | Kidney Int. | pmid:17622274 |
| Vikrant S | Optimum dosage regimen for iron sucrose. | 2007 | Kidney Int. | pmid:17625585 |
| Yew WS et al. | Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. | 2007 | Biochemistry | pmid:17649980 |
| Reed J et al. | The safety of intravenous iron sucrose use in the elderly patient. | 2007 | Consult Pharm | pmid:17658969 |
| Shaheen FA et al. | Effect of intravenous iron saccharate on the requirements of erythropoietin in hemodialysis patients. | 2002 Apr-Jun | Saudi J Kidney Dis Transpl | pmid:17660651 |
| Thomas J and Martinez A | Blood conservation in the critically ill. | 2007 | Am J Health Syst Pharm | pmid:17687066 |
| Singh H et al. | Effect of intravenous iron sucrose in peritoneal dialysis patients who receive erythropoiesis-stimulating agents for anemia: a randomized, controlled trial. | 2006 | Clin J Am Soc Nephrol | pmid:17699248 |
| Bishu K and Agarwal R | Acute injury with intravenous iron and concerns regarding long-term safety. | 2006 | Clin J Am Soc Nephrol | pmid:17699372 |
| Zager RA | Parenteral iron compounds: potent oxidants but mainstays of anemia management in chronic renal disease. | 2006 | Clin J Am Soc Nephrol | pmid:17699373 |
| Tryfinopoulou P et al. | Diversity of Shewanella population in fish Sparus aurata harvested in the Aegean Sea. | 2007 | J. Appl. Microbiol. | pmid:17714405 |
| Vindal V et al. | GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. | 2007 | BMC Genomics | pmid:17714599 |
| Breymann C | Treatment of iron deficiency anaemia in pregnancy and postpartum with special focus on intravenous iron sucrose complex. | 2005 | J Med Assoc Thai | pmid:17718296 |
| Grzegorzewska AE | [Administration of iron-containing drugs in non-dialyzed patients with chronic kidney disease]. | 2007 | Pol. Arch. Med. Wewn. | pmid:17722476 |
| Singh J and Gupta KP | Induction of apoptosis by calcium D-glucarate in 7,12-dimethyl benz [a] anthracene-exposed mouse skin. | 2007 | J. Environ. Pathol. Toxicol. Oncol. | pmid:17725531 |
| Malindretos P et al. | Slow intravenous iron administration does not aggravate oxidative stress and inflammatory biomarkers during hemodialysis: a comparative study between iron sucrose and iron dextran. | 2007 | Am. J. Nephrol. | pmid:17804904 |
| Olas B et al. | D-glucaro 1,4-lactone and resveratrol as antioxidants in blood platelets. | 2008 | Cell Biol. Toxicol. | pmid:17846905 |
| Sato K | [Drug-induced osteomalacia]. | 2007 | Clin Calcium | pmid:17906405 |
| Saluk-Juszczak J et al. | Protective effects of D-glucaro-1,4-lactone against oxidative modifications in blood platelets. | 2008 | Nutr Metab Cardiovasc Dis | pmid:17933501 |
| Teschke O et al. | Quorum sensing detected by atomic force microscopy imaging of corrals surrounding multicellular arrangement of bacteria. | 2008 | Microsc. Res. Tech. | pmid:17943987 |
| Toblli JE et al. | Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency. | 2007 | J. Am. Coll. Cardiol. | pmid:17950147 |
| Francis GS and Kanderian A | Anemia and heart failure a new pathway? | 2007 | J. Am. Coll. Cardiol. | pmid:17950148 |
| Wang S et al. | Chemical reactions of vitamin C with intravenous-iron formulations. | 2008 | Nephrol. Dial. Transplant. | pmid:17951305 |
| pmid:17994454 | ||||
| Franco G et al. | Behaviour of urinary D-glucaric acid excretion in surgical patients and anaesthesiology staff acutely exposed to isoflurane and nitrous oxide. | 1991 Nov-Dec | Med Lav | pmid:1803214 |