Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Roth S et al. | Comparative toxicity and cell-tissue distribution study on nanoparticular iron complexes using avian embryos and HepG2-cells. | 2008 | Transl Res | pmid:18061126 |
| Liu Z et al. | Evaluating the protective role of ischaemic preconditioning in rat hearts using a stationary small-animal SPECT imager and 99mTc-glucarate. | 2008 | Nucl Med Commun | pmid:18094633 |
| pmid:18118003 | ||||
| Hasegawa K et al. | [Improvement of urinary d-glucaric acid assay and its application]. | 2008 | Yakugaku Zasshi | pmid:18176065 |
| Wall GC and Pauly RA | Evaluation of total-dose iron sucrose infusions in patients with iron deficiency anemia. | 2008 | Am J Health Syst Pharm | pmid:18192261 |
| Pai AB et al. | Effect of intravenous iron supplementation on hepatic cytochrome P450 3A4 activity in hemodialysis patients: a prospective, open-label study. | 2007 | Clin Ther | pmid:18201586 |
| Al-Mueilo SH | Beneficial effects of maintenance intravenous iron saccharate in hemodialysis patients. | 2005 Apr-Jun | Saudi J Kidney Dis Transpl | pmid:18202490 |
| Al-Saran KA and Sabry AA | Pregnancy in dialysis patients: a case series. | 2008 | J Med Case Rep | pmid:18205953 |
| pmid:18208026 | ||||
| Zolezzi M | Intravenous Iron Saccharate Complex: Guidelines for its use in the Management of Anemia of Renal Disease. | 2003 Apr-Jun | Saudi J Kidney Dis Transpl | pmid:18209437 |
| Souqiyyeh MZ and Shaheen FA | Attitude of physicians towards iron supplementation in hemodialysis patients treated with erythropoietin. | 2003 Apr-Jun | Saudi J Kidney Dis Transpl | pmid:18209438 |
| Li H and Wang SX | Intravenous iron sucrose in Chinese hemodialysis patients with renal anemia. | 2008 | Blood Purif. | pmid:18212498 |
| Jaber BL | Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease. | 2008 | Kidney Int. | pmid:18235527 |
| Bhatnagar R et al. | Growth suppression of human breast carcinoma cells in culture by N-(4-hydroxyphenyl)retinamide and its glucuronide and through synergism with glucarate. | 1991 | Biochem. Pharmacol. | pmid:1826840 |
| Auerbach M and Al Talib K | Low-molecular weight iron dextran and iron sucrose have similar comparative safety profiles in chronic kidney disease. | 2008 | Kidney Int. | pmid:18274543 |
| Earley CJ et al. | A randomized, double-blind, placebo-controlled trial of intravenous iron sucrose in restless legs syndrome. | 2009 | Sleep Med. | pmid:18280205 |
| Li H and Wang SX | Intravenous iron sucrose in peritoneal dialysis patients with renal anemia. | 2008 Mar-Apr | Perit Dial Int | pmid:18332450 |
| Perek N et al. | Could 99mTc-glucarate be used to evaluate tumour necrosis? In vitro and in vivo studies in leukaemic tumour cell line U937. | 2008 | Eur. J. Nucl. Med. Mol. Imaging | pmid:18338166 |
| Lim R et al. | A permanent tan from iron. | 2008 | Kidney Int. | pmid:18340355 |
| Auerbach M et al. | The role of intravenous iron in anemia management and transfusion avoidance. | 2008 | Transfusion | pmid:18346021 |
| Aghaie A et al. | New insights into the alternative D-glucarate degradation pathway. | 2008 | J. Biol. Chem. | pmid:18364348 |
| pmid:18384797 | ||||
| Usmanov RI et al. | Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency. | 2008 Mar-Apr | J. Nephrol. | pmid:18446719 |
| Willerson JT | Detection of acute myocardial infarcts by infarct-avid imaging. | 1991 | J. Nucl. Med. | pmid:1846912 |
| Hedenus M and Birgegård G | The role of iron supplementation during epoietin treatment for cancer-related anemia. | 2009 | Med. Oncol. | pmid:18473194 |
| Kuo KL et al. | Intravenous iron exacerbates oxidative DNA damage in peripheral blood lymphocytes in chronic hemodialysis patients. | 2008 | J. Am. Soc. Nephrol. | pmid:18495964 |
| Picker SM et al. | Effects of Mirasol PRT treatment on storage lesion development in plasma-stored apheresis-derived platelets compared to untreated and irradiated units. | 2008 | Transfusion | pmid:18513255 |
| pmid:18571185 | ||||
| Cuenca J et al. | Efficacy of intravenous iron sucrose administration for correcting preoperative anemia in patients scheduled for major orthopedic surgery. | 2008 | Anesthesiology | pmid:18580186 |
| Auerbach M and Ballard H | Intravenous iron in oncology. | 2008 | J Natl Compr Canc Netw | pmid:18597712 |
| Pinsk V et al. | Efficacy and safety of intravenous iron sucrose therapy in a group of children with iron deficiency anemia. | 2008 | Isr. Med. Assoc. J. | pmid:18605353 |
| Kaplinsky C | Parenteral iron therapy. | 2008 | Isr. Med. Assoc. J. | pmid:18605363 |
| Costa S et al. | In vitro evaluation of the chemoprotective action mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenol-induced cell damage. | 2009 | J Appl Toxicol | pmid:18636399 |
| Anirban G et al. | The comparative safety of various intravenous iron preparations in chronic kidney disease patients. | 2008 | Ren Fail | pmid:18661414 |
| Oleson L and Court MH | Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases. | 2008 | J. Pharm. Pharmacol. | pmid:18718121 |
| pmid:18720044 | ||||
| pmid:18727354 | ||||
| Zółtaszek R et al. | [The biological role of D-glucaric acid and its derivatives: potential use in medicine]. | 2008 | Postepy Hig Med Dosw (Online) | pmid:18772850 |
| Stefánsson BV et al. | Ascorbyl free radical reflects catalytically active iron after intravenous iron saccharate injection. | 2008 | Free Radic. Biol. Med. | pmid:18775775 |
| pmid:18786076 | ||||
| Yang Z et al. | Symbiosis between microorganisms from kombucha and kefir: Potential significance to the enhancement of kombucha function. | 2010 | Appl. Biochem. Biotechnol. | pmid:18810658 |
| pmid:18930421 | ||||
| Lord RS and Bralley JA | Clinical applications of urinary organic acids. Part I: Detoxification markers. | 2008 | Altern Med Rev | pmid:18950247 |
| Young RS | Determination of calcium oxide in calcined phosphate ores. | 1973 | Talanta | pmid:18961359 |
| Bolaños L et al. | Intravenous iron sucrose does not impair sonographic brachial vasodilation in peritoneal dialysis patients. | 2008 | Adv Perit Dial | pmid:18986009 |
| Gonçalves P et al. | The effect of high glucose on SERT, the human plasmalemmal serotonin transporter. | 2008 | Nutr Neurosci | pmid:19000377 |
| Yoon SH et al. | Cloning and characterization of uronate dehydrogenases from two pseudomonads and Agrobacterium tumefaciens strain C58. | 2009 | J. Bacteriol. | pmid:19060141 |
| Moon TS et al. | Production of glucaric acid from a synthetic pathway in recombinant Escherichia coli. | 2009 | Appl. Environ. Microbiol. | pmid:19060162 |
| pmid:19066859 | ||||
| Kell DB | Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. | 2009 | BMC Med Genomics | pmid:19133145 |
| Ibrahim HN et al. | Parenteral iron use: possible contribution to exceeding target hemoglobin in hemodialysis patients. | 2009 | Clin J Am Soc Nephrol | pmid:19211669 |
| Haddad A et al. | Use of iron sucrose in dialysis patients sensitive to iron dextran. | 2009 | Saudi J Kidney Dis Transpl | pmid:19237805 |
| Pollak VE et al. | The importance of iron in long-term survival of maintenance hemodialysis patients treated with epoetin-alfa and intravenous iron: analysis of 9.5 years of prospectively collected data. | 2009 | BMC Nephrol | pmid:19245700 |
| Torres-Corzo JG et al. | Comparison of cerebrospinal fluid obtained by ventricular endoscopy and by lumbar puncture in patients with hydrocephalus secondary to neurocysticercosis. | 2009 | Surg Neurol | pmid:19249584 |
| Clark SF | Iron deficiency anemia: diagnosis and management. | 2009 | Curr. Opin. Gastroenterol. | pmid:19262200 |
| Muñoz M et al. | [Usefulness of the administration of intravenous iron sucrose for the correction of preoperative anemia in major surgery patients]. | 2009 | Med Clin (Barc) | pmid:19264195 |
| Vanin S et al. | Seasonal variation of trehalose and glycerol concentrations in winter snow-active insects. | 2008 Nov-Dec | Cryo Letters | pmid:19280052 |
| Breborowicz A et al. | Intravenous iron sucrose changes the intraperitoneal homeostasis. | 2009 | Blood Purif. | pmid:19325240 |
| Lindgren S et al. | Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: A randomized, controlled, evaluator-blind, multicentre study. | 2009 | Scand. J. Gastroenterol. | pmid:19330567 |
| Kim YH et al. | Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study. | 2009 | Acta Haematol. | pmid:19332985 |
| Zanor MI et al. | Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. | 2009 | J. Exp. Bot. | pmid:19346240 |
| Gorder V et al. | Treatment of restless legs syndrome with iron infusion therapy. | 2009 | JAAPA | pmid:19354112 |
| Nakamura Y et al. | Decreased valproate level caused by VPA-glucuronidase inhibition by carbapenem antibiotics. | 2008 | Drug Metab Lett | pmid:19356106 |
| De Saint-Hubert M et al. | Molecular imaging of cell death. | 2009 | Methods | pmid:19362149 |
| pmid:19379368 | ||||
| Bencaiova G et al. | Iron prophylaxis in pregnancy: intravenous route versus oral route. | 2009 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:19406557 |
| pmid:19432851 | ||||
| Luo Z et al. | Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells. | 2009 | Endocrine | pmid:19440859 |
| pmid:19481054 | ||||
| Grote L et al. | A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome. | 2009 | Mov. Disord. | pmid:19489063 |
| Kulnigg S et al. | Rapid recurrence of IBD-associated anemia and iron deficiency after intravenous iron sucrose and erythropoietin treatment. | 2009 | Am. J. Gastroenterol. | pmid:19491860 |
| Asma S et al. | Safety, therapeutic effectiveness, and cost of parenteral iron therapy. | 2009 | Int. J. Hematol. | pmid:19495930 |
| GarcÃa-Erce JA et al. | Efficacy of preoperative recombinant human erythropoietin administration for reducing transfusion requirements in patients undergoing surgery for hip fracture repair. An observational cohort study. | 2009 | Vox Sang. | pmid:19497085 |
| Nguyen TV | Comparison of serum ferritin and transferrin saturation values associated with two i.v. iron formulations in hemodialysis patients. | 2009 | Am J Health Syst Pharm | pmid:19498125 |
| Fontés G et al. | Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. | 2009 | Diabetes | pmid:19502418 |
| Krafft A et al. | Selective use of recombinant human erythropoietin in pregnant patients with severe anemia or nonresponsive to iron sucrose alone. | 2009 | Fetal. Diagn. Ther. | pmid:19506383 |
| Toblli JE et al. | Differences between original intravenous iron sucrose and iron sucrose similar preparations. | 2009 | Arzneimittelforschung | pmid:19517894 |
| Shimizu Y et al. | Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. | 2009 | Bone | pmid:19555782 |
| Li H and Wang SX | [Intravenous iron sucrose in maintenance dialysis patients with renal anemia: a clinical study]. | 2009 | Zhonghua Yi Xue Za Zhi | pmid:19567093 |
| Yi CX et al. | A major role for perifornical orexin neurons in the control of glucose metabolism in rats. | 2009 | Diabetes | pmid:19592616 |
| Barraclough KA et al. | Rationale and design of the oral HEMe iron polypeptide Against Treatment with Oral Controlled Release Iron Tablets trial for the correction of anaemia in peritoneal dialysis patients (HEMATOCRIT trial). | 2009 | BMC Nephrol | pmid:19635169 |
| Dueber JE et al. | Synthetic protein scaffolds provide modular control over metabolic flux. | 2009 | Nat. Biotechnol. | pmid:19648908 |
| Dong T and Schellhorn HE | Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933. | 2009 | BMC Genomics | pmid:19650909 |
| DeLisa MP and Conrado RJ | Synthetic metabolic pipelines. | 2009 | Nat. Biotechnol. | pmid:19668178 |
| pmid:19717754 | ||||
| Edwards TJ et al. | Randomized clinical trial of preoperative intravenous iron sucrose to reduce blood transfusion in anaemic patients after colorectal cancer surgery. | 2009 | Br J Surg | pmid:19731228 |
| Gehret TC et al. | Convenient large-scale synthesis of D-glucaro-1,4:6,3-dilactone. | 2009 | J. Org. Chem. | pmid:19777999 |
| Muñoz M et al. | Intravenous iron in inflammatory bowel disease. | 2009 | World J. Gastroenterol. | pmid:19787830 |
| Smith TG et al. | Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials. | 2009 | JAMA | pmid:19809026 |
| ComÃn-Colet J et al. | A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: influence on neurohormonal activation and clinical outcomes. | 2009 | J. Card. Fail. | pmid:19879457 |
| Ball LM et al. | Formation of mutagenic urinary metabolites from 1-nitropyrene in germ-free and conventional rats: role of the gut flora. | 1991 | Carcinogenesis | pmid:1988167 |
| McMahon LP et al. | Maintenance of elevated versus physiological iron indices in non-anaemic patients with chronic kidney disease: a randomized controlled trial. | 2010 | Nephrol. Dial. Transplant. | pmid:19906658 |
| Orlandi C et al. | Early scintigraphic detection of experimental myocardial infarction in dogs with technetium-99m-glucaric acid. | 1991 | J. Nucl. Med. | pmid:1992031 |
| Morimoto S et al. | Significance of urinary glucaric acid measurement and its application to paclitaxel therapy. | 2009 | Gan To Kagaku Ryoho | pmid:19920388 |
| Gambini JP et al. | Evaluation of patients with head and neck cancer by means of 99mTc-glucarate. | 2009 | J Nucl Med Technol | pmid:19949020 |
| Stancu S et al. | Can the response to iron therapy be predicted in anemic nondialysis patients with chronic kidney disease? | 2010 | Clin J Am Soc Nephrol | pmid:20019121 |
| Sienkiewicz-Porzucek A et al. | Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth. | 2010 | Mol Plant | pmid:20035036 |
| Fior S and Gerola PD | Impact of ubiquitous inhibitors on the GUS gene reporter system: evidence from the model plants Arabidopsis, tobacco and rice and correction methods for quantitative assays of transgenic and endogenous GUS. | 2009 | Plant Methods | pmid:20042078 |
| Ginsberg G and Rice DC | Does rapid metabolism ensure negligible risk from bisphenol A? | 2009 | Environ. Health Perspect. | pmid:20049111 |
| Dangsuwan P and Manchana T | Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy. | 2010 | Gynecol. Oncol. | pmid:20051288 |