Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ohnhaus EE et al. | The effect of antipyrine, phenobarbitol and rifampicin on thyroid hormone metabolism in man. | 1981 | Eur. J. Clin. Invest. | pmid:6800809 |
Richens A et al. | Effects of sodium valproate on the serum protein binding of phenytoin, and on liver enzyme activity. | 1980 | Monogr Neural Sci | pmid:6798427 |
Matsuoka S et al. | Correlation between the level of urinary D-glucaric acid and the degree of activation of masked compound (FT-207) in cancer patients. | 1981 | Tohoku J. Exp. Med. | pmid:6797104 |
Németh I et al. | Hyperbilirubinemia and urinary D-glucaric acid excretion in premature infants following antepartum dexamethasone treatment. | 1981 | J Perinat Med | pmid:6783743 |
Gargan R et al. | A concise biotyping system for differentiating strains of Escherichia coli. | 1982 | J. Clin. Pathol. | pmid:6757274 |
Loi AM et al. | [Urinary secretion of D-glucaric acid in subjects exposed to styrene]. | 1984 Mar-Apr | Med Lav | pmid:6749047 |
Nakajima M et al. | Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase. | 1984 | J. Biol. Chem. | pmid:6698965 |
Freundt KJ | Variable inhibition of human hepatic drug metabolizing enzymes by disulfiram. | 1978 | Int J Clin Pharmacol Biopharm | pmid:669879 |
Gachályi B et al. | m-Trifluoromethyl-alpha-ethylbenzhydrol: a new enzyme inducer. | 1978 | Eur. J. Clin. Pharmacol. | pmid:668788 |
Vezekenyi Z et al. | Human tolerance of flumecinol (Zixoryn, RGH-3332), its regime and dosage in healthy volunteers. | 1983 | Int J Clin Pharmacol Res | pmid:6679516 |
Horváth T et al. | Correlation between biochemical tests, parameters of drug elimination and hepatic enzyme induction in chronic liver diseases. | 1983 | Acta Med Hung | pmid:6674914 |
Laakso EI et al. | Determination of D-glucaric acid by high-performance liquid chromatography. | 1983 | J. Chromatogr. | pmid:6668320 |
Soldato PD and Meli A | Studies on the mechanism of fat-free diet (FFD) protection against indomethacin-induced intestinal ulcers. | 1978 | Proc. Soc. Exp. Biol. Med. | pmid:662870 |
Isomatsu Y et al. | [Clinical study on prophylaxis of diacetyl-glucaro-(1-4) (6-3) dilactone for recurrence of bladder cancer]. | 1983 | Gan To Kagaku Ryoho | pmid:6614934 |
Dolara P et al. | Enzyme induction in humans exposed to styrene. | 1983 | Ann Occup Hyg | pmid:6614729 |
Higashi T et al. | [Relative Ga-67 image enhancement by iron-loading]. | 1984 | Kaku Igaku | pmid:6593479 |
Oberhaensli RD et al. | Different actions of deferoxamine and iron on Ga-67 abscess detection in rats. | 1984 | J. Nucl. Med. | pmid:6587029 |
Stevens PM et al. | Urinary D-glucaric acid and oral contraceptives. | 1978 | Br J Clin Pharmacol | pmid:656297 |
Wang CY and Hayashida S | Enhancement by phenothiazine and 2,5-di-O-acetyl-D-glucosaccharo-(1,4)(6,3)-dilactone of bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in rats. | 1984 | Cancer Lett. | pmid:6548659 |
Hrubisko M et al. | Drug resistance induction and cross-resistance studies with Pt-complexes. | 1984 | Neoplasma | pmid:6542968 |
Freundt KJ et al. | Concentrations of D-glucaric acid in human urine after repeated administration of pyrithioxine. | 1984 | Int J Clin Pharmacol Ther Toxicol | pmid:6526537 |
Miyawaki M et al. | Absorption of experimentally administered materials by the hepatopancreas cells of the crayfish, Procambarus clarki. | 1984 | Cell Biol. Int. Rep. | pmid:6509562 |
Houin G and Tillement JP | Clofibrate and enzymatic induction in man. | 1978 | Int J Clin Pharmacol Biopharm | pmid:649234 |
Imamura K | Effects of intravenous administration of iron preparations on the metabolism of phosphorus. Comparative study on 3 iron preparations. | 1984 | Fukuoka Igaku Zasshi | pmid:6489911 |
Gachályi B et al. | Effect of a non-steroid anti-inflammatory agent on the drug metabolizing activity of the human liver. | 1984 | Int J Clin Pharmacol Ther Toxicol | pmid:6469424 |
Várkonyi A et al. | Non-specific drug-metabolizing enzyme activity in Gilbert disease. | 1984 | Acta Med Hung | pmid:6440117 |
Perucca E et al. | A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. | 1984 | Br J Clin Pharmacol | pmid:6435654 |
Fujita M et al. | Cancer-associated alteration of beta-glucuronidase in human lung cancer: elevated activity and increased phosphorylation. | 1984 | Gan | pmid:6432619 |
Walters DG et al. | Direct determination of D-[U-14C] glucaric acid in urine by ion-exchange high-performance liquid chromatography. | 1983 | J. Chromatogr. | pmid:6423654 |
Ryzewski CN and Malejka-Giganti D | A novel assay of glucuronidation of C- and N-hydroxylated metabolites of the carcinogen N-2-fluorenylacetamide. | 1983 | Anal. Biochem. | pmid:6408946 |
Horváth T et al. | Investigation of biotransformation capacity in patients with chronic liver diseases by pharmacokinetic methods: experimental trials. | 1984 Jul-Aug | Pol J Pharmacol Pharm | pmid:6396596 |
Kimbrough RD | The epidemiology and toxicology of TCDD. | 1984 | Bull Environ Contam Toxicol | pmid:6240288 |
Martin JV | Lipid abnormalities in workers exposed to dioxin. | 1984 | Br J Ind Med | pmid:6232943 |
pmid:6209078 | ||||
Walaszek Z et al. | Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumorigenesis by 2,5-di-O-acetyl-D-glucaro-1,4:6,3-dilactone, an in vivo beta-glucuronidase inhibitor. | 1984 | Carcinogenesis | pmid:6202433 |
Carrella M et al. | An evaluation of urinary D-glucaric acid excretion during acute hepatitis in man. | 1978 | Am J Dig Dis | pmid:619622 |
Arató M and Varadi A | On the possible role of enzyme induction in cases of resistancy to chlorpromazine treatment. | 1977 | Pharmakopsychiatr Neuropsychopharmakol | pmid:616930 |
Guzelian PS et al. | Liver structure and function in patients poisoned with chlordecone (Kepone). | 1980 | Gastroenterology | pmid:6153073 |
Pár A et al. | Inhibition of hepatic drug metabolism by (+)-cyanidanol-3 (Catergen) in chronic alcoholic liver disease. | 1984 | Acta Physiol Hung | pmid:6152369 |
Maroni M et al. | Evaluation of porphyrinogenesis and enzyme induction in workers exposed to PCB. | 1984 May-Jun | Med Lav | pmid:6148686 |
Jung K and Scholz D | Increased serum gamma-glutamyltransferase activity in renal transplant recipients: liver damage or microsomal enzyme induction? | 1984 | Clin. Chim. Acta | pmid:6147212 |
Tutor JC et al. | [Calcium metabolism and liver enzyme induction in patients treated with anticonvulsant drugs]. | 1984 | Med Clin (Barc) | pmid:6145829 |
Perry W and Stamp TC | Urinary D-glucaric acid excretion during rifampicin/isoniazid and anticonvulsant enzyme induction. | 1984 | Clin. Pharmacol. Ther. | pmid:6143635 |
Døssing M | Noninvasive assessment of microsomal enzyme activity in occupational medicine: present state of knowledge and future perspectives. | 1984 | Int Arch Occup Environ Health | pmid:6142865 |
Peduto VA et al. | Stimulation of drug-metabolizing enzymes by nitrous oxide in the rat. | 1983 | Acta Anaesthesiol Scand | pmid:6141696 |
de Wolff FA et al. | The effects of valproic acid on liver function. | 1983 | Arch. Toxicol. Suppl. | pmid:6138013 |
Wright JH et al. | Hepatic enzyme induction patterns and phenothiazine side effects. | 1983 | Clin. Pharmacol. Ther. | pmid:6137306 |
Kawasaki H et al. | Effects of phenobarbital on unconjugated bilirubin clearance, gamma-glutamyltranspeptidase and urinary d-glucaric acid in patients with Gilbert's syndrome. | 1982 | Hepatogastroenterology | pmid:6130037 |
Park BK | Assessment of the drug metabolism capacity of the liver. | 1982 | Br J Clin Pharmacol | pmid:6128018 |
Jung K et al. | [D-glucaric acid excretion in kidney transplant patients as an indicator of microsomal enzyme capacity]. | 1982 | Z Urol Nephrol | pmid:6126971 |