Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sanai T et al. | Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats. | 2005 | J. Lab. Clin. Med. | pmid:16025088 |
Bontchev RP and Moore RC | Crystal structure and aqueous solubility of ammonium D-glucarate. | 2005 | Carbohydr. Res. | pmid:16043161 |
Wood DM et al. | Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child. | 2005 | Ther Drug Monit | pmid:16044093 |
Macdougall IC and Roche A | Administration of intravenous iron sucrose as a 2-minute push to CKD patients: a prospective evaluation of 2,297 injections. | 2005 | Am. J. Kidney Dis. | pmid:16112047 |
Perek N et al. | MRP-1 protein expression and glutathione content of in vitro tumor cell lines derived from human glioma carcinoma U-87-MG do not interact with 99mTc-glucarate uptake. | 2005 | Cancer Biother. Radiopharm. | pmid:16114987 |
Zager RA | Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy. | 2005 | Kidney Int. | pmid:16164630 |
Erichsen K et al. | Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. | 2005 | Scand. J. Gastroenterol. | pmid:16165718 |
Strolin Benedetti M et al. | Induction of endogenous pathways by antiepileptics and clinical implications. | 2005 | Fundam Clin Pharmacol | pmid:16176329 |
St Peter WL et al. | Trends in intravenous iron use among dialysis patients in the United States (1994-2002). | 2005 | Am. J. Kidney Dis. | pmid:16183420 |
Ayotte P et al. | Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. | 2005 | Environ. Health Perspect. | pmid:16203240 |
Ozdemir A et al. | Relationship between iron replacement and hepatic functions in hepatitis C virus-positive chronic haemodialysis patients. | 2005 | Nephrology (Carlton) | pmid:16221090 |
Spiegel K et al. | Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. | 2005 | J. Appl. Physiol. | pmid:16227462 |
Johnson G et al. | (99m)Tc-glucarate imaging for the early detection of infarct in partially reperfused canine myocardium. | 2006 | Eur. J. Nucl. Med. Mol. Imaging | pmid:16237571 |
Aime S et al. | para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents. | 2005 | Org. Biomol. Chem. | pmid:16240012 |
Glassman E | Oral iron therapy with ferrous fumarate and polysaccharide iron complex. | 1992 | ANNA J | pmid:1627011 |
Georgopoulos D et al. | Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317]. | 2005 | Crit Care | pmid:16277712 |
Schröder O et al. | Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease--a randomized, controlled, open-label, multicenter study. | 2005 | Am. J. Gastroenterol. | pmid:16279906 |
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pmid:16286429 | ||||
Tutor-Crespo MJ et al. | Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects. | 2005 | J. Pharmacol. Sci. | pmid:16314692 |
Schaller G et al. | Intravenous iron increases labile serum iron but does not impair forearm blood flow reactivity in dialysis patients. | 2005 | Kidney Int. | pmid:16316358 |
Van Wyck DB et al. | A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. | 2005 | Kidney Int. | pmid:16316362 |
Laman CA et al. | Parenteral iron therapy: a single institution's experience over a 5-year period. | 2005 | J Natl Compr Canc Netw | pmid:16316614 |
Anemia during pregnancy and in the postpartum: intravenous iron therapy revisited. | 2005 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:16360535 | |
Govan AD and Scott JM | Intravenous iron in the treatment of anemia of pregnancy. 1949. | 2005 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:16360540 |
Karkouti K et al. | Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia. | 2006 | Can J Anaesth | pmid:16371604 |
Zheng H et al. | Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects. | 2006 | Kidney Int. | pmid:16395269 |
pmid:16417257 | ||||
Hoyle VR et al. | Studies on the biochemical effects of the aldose reductase inhibitor 2,7-difluorospirofluorene-9,5'-imidazolidine-2',4'-dione (Al 1576, HOE 843). Detection of D-glucaric and D-glucuronic acid excretion by high resolution 1H and 13C NMR spectroscopy. | 1992 | Biochem. Pharmacol. | pmid:1642638 |
Anbu AT et al. | Low incidence of adverse events following 90-minute and 3-minute infusions of intravenous iron sucrose in children on erythropoietin. | 2005 | Acta Paediatr. | pmid:16431410 |
Cançado RD et al. | [Evaluation of the efficacy of intravenous iron III-hydroxide saccharate for treating adult patients with iron deficiency anemia]. | 2005 Nov-Dec | Rev Assoc Med Bras (1992) | pmid:16444338 |
pmid:16504354 | ||||
Brown SD et al. | A gold standard set of mechanistically diverse enzyme superfamilies. | 2006 | Genome Biol. | pmid:16507141 |
pmid:16522172 | ||||
Koutroubakis IE et al. | Effectiveness of darbepoetin-alfa in combination with intravenous iron sucrose in patients with inflammatory bowel disease and refractory anaemia: a pilot study. | 2006 | Eur J Gastroenterol Hepatol | pmid:16538115 |
Agarwal R | Proinflammatory effects of iron sucrose in chronic kidney disease. | 2006 | Kidney Int. | pmid:16609688 |
Muñoz M et al. | Role of parenteral iron in transfusion requirements after total hip replacement. A pilot study. | 2006 | Transfus Med | pmid:16623920 |
Sudan C et al. | Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants. | 2006 | Planta | pmid:16652220 |
Strack D et al. | Enzymic synthesis of caffeoylglucaric Acid from chlorogenic Acid and glucaric Acid by a protein preparation from tomato cotyledons. | 1987 | Plant Physiol. | pmid:16665274 |
Guz G et al. | Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients. | 2006 | Nephrol. Dial. Transplant. | pmid:16762960 |
Barton Pai A et al. | Non-transferrin-bound iron is associated with enhanced Staphylococcus aureus growth in hemodialysis patients receiving intravenous iron sucrose. | 2006 | Am. J. Nephrol. | pmid:16809897 |
Coletta AP et al. | Clinical trials update from the European Society of Cardiology heart failure meeting: TNT subgroup analysis, darbepoetin alfa, FERRIC-HF and KW-3902. | 2006 | Eur. J. Heart Fail. | pmid:16887387 |
Schiesser D et al. | Weekly low-dose treatment with intravenous iron sucrose maintains iron status and decreases epoetin requirement in iron-replete haemodialysis patients. | 2006 | Nephrol. Dial. Transplant. | pmid:16891647 |
Kato M et al. | Tetranuclear copper(II) complexes bridged by alpha-D-glucose-1-phosphate and incorporation of sugar acids through the Cu4 core structural changes. | 2006 | Inorg Chem | pmid:16903719 |
Carlini RG et al. | Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro. | 2006 | Nephrol. Dial. Transplant. | pmid:16957011 |
Agarwal R | Is i.v. iron really superior in CKD patients not on dialysis? | 2006 | Kidney Int. | pmid:16957750 |
Davey CL et al. | Esterification of select polyols with D-glucaric acid as model reactions for esterification of starch. | 2006 | Carbohydr. Res. | pmid:16973136 |
Bolger AP et al. | Intravenous iron alone for the treatment of anemia in patients with chronic heart failure. | 2006 | J. Am. Coll. Cardiol. | pmid:16979010 |
GarcÃa-Erce JA et al. | Perioperative intravenous iron preserves iron stores and may hasten the recovery from post-operative anaemia after knee replacement surgery. | 2006 | Transfus Med | pmid:16999756 |
Bhandal N and Russell R | Intravenous versus oral iron therapy for postpartum anaemia. | 2006 | BJOG | pmid:17004982 |