Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Rowlands M et al. | The effect of intravenous iron on postoperative transfusion requirements in hip fracture patients: study protocol for a randomized controlled trial. | 2013 | Trials | pmid:24015990 |
Abdel-Razeq H et al. | Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study. | 2013 | Drug Des Devel Ther | pmid:24039403 |
Kalaivani K | Use of intravenous iron sucrose for treatment of anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056552 |
Kriplani A et al. | Intravenous iron sucrose therapy for moderate to severe anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056559 |
Palmer K et al. | Review of available intravenous iron preparations in hemodialysis. | 2013 Apr-Jun | CANNT J | pmid:24069699 |
Michigami T | [Updates on rickets and osteomalacia: FGF23-mediated hypophosphatemic rickets/osteomalacia]. | 2013 | Clin Calcium | pmid:24076640 |
pmid:24081613 | ||||
pmid:24087940 | ||||
Athibovonsuk P et al. | Prevention of blood transfusion with intravenous iron in gynecologic cancer patients receiving platinum-based chemotherapy. | 2013 | Gynecol. Oncol. | pmid:24099839 |
Guzelian PS | Clinical evaluation of liver structure and function in humans exposed to halogenated hydrocarbons. | 1985 | Environ. Health Perspect. | pmid:2411535 |
Ferumoxytol: an intravenous iron, riskier than iron sucrose. | 2013 | Prescrire Int | pmid:24171212 | |
Lu QY et al. | Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase. | 2014 | J Pharm Biomed Anal | pmid:24176739 |
pmid:24219061 | ||||
Toyokuni S | Iron overload as a major targetable pathogenesis of asbestos-induced mesothelial carcinogenesis. | 2014 | Redox Rep. | pmid:24257681 |
Sasaki Y et al. | Hepcidin production in response to iron is controlled by monocyte-derived humoral factors. | 2014 | Int. J. Hematol. | pmid:24293278 |
pmid:24333274 | ||||
Soufras GD et al. | Fatal anaphylactic reaction to iron sucrose in pregnancy: iron-induced Kounis syndrome? | 2013 Nov-Dec | Indian J Pharmacol | pmid:24347784 |
Italia K et al. | Hydroxyurea could be a good clinically relevant iron chelator. | 2013 | PLoS ONE | pmid:24349400 |
Balling A et al. | [Chronic hemorrhagic iron deficiency. Sources of hemorrhage, blood loss and systematic iron substitution]. | 1987 | Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. | pmid:2440780 |
Perelló MF et al. | Intravenous ferrous sucrose versus placebo in addition to oral iron therapy for the treatment of severe postpartum anaemia: a randomised controlled trial. | 2014 | BJOG | pmid:24423186 |
Shah RB et al. | Pharmaceutical characterization and thermodynamic stability assessment of a colloidal iron drug product: iron sucrose. | 2014 | Int J Pharm | pmid:24440404 |
Macdougall IC et al. | A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD. | 2014 | Clin J Am Soc Nephrol | pmid:24458078 |
pmid:24535226 | ||||
pmid:24566860 | ||||
pmid:24588937 | ||||
pmid:24611780 | ||||
Hetzel D et al. | A Phase III, randomized, open-label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy. | 2014 | Am. J. Hematol. | pmid:24639149 |
Wagner G and Hollmann S | Uronic acid dehydrogenase from Pseudomonas syringae. Purification and properties. | 1976 | Eur. J. Biochem. | pmid:2471 |
Kuo KL et al. | Iron sucrose accelerates early atherogenesis by increasing superoxide production and upregulating adhesion molecules in CKD. | 2014 | J. Am. Soc. Nephrol. | pmid:24722448 |
pmid:24725852 | ||||
pmid:24765889 | ||||
Oredipe OA et al. | Chemopreventative activity of dietary glucarate on azoxymethane-induced altered hepatic foci in rats. | 1989 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:2479062 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Florey L | The uptake of particulate matter by endothelial cells. | 1967 | Proc. R. Soc. Lond., B, Biol. Sci. | pmid:24796034 |
Pieracci FM et al. | A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. | 2014 | Crit. Care Med. | pmid:24797376 |
pmid:24816781 | ||||
Ferioli A et al. | Alteration of steroid hormone sulfation and D-glucaric acid excretion in lead workers. | 1989 Jul-Sep | Biol Trace Elem Res | pmid:2484601 |
pmid:24972288 | ||||
pmid:25036548 | ||||
pmid:25050519 | ||||
Price E et al. | A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200 ng/mL. | 2014 | Blood Cells Mol. Dis. | pmid:25065855 |
Dwivedi C et al. | Modulation of chemically initiated and promoted skin tumorigenesis in CD-1 mice by dietary glucarate. | 1989 May-Jun | J. Environ. Pathol. Toxicol. Oncol. | pmid:2509679 |
pmid:25123238 | ||||
Corwin HL and Napolitano LM | Anemia in the critically ill: do we need to live with it?*. | 2014 | Crit. Care Med. | pmid:25126804 |
Beguin Y and Jaspers A | Iron sucrose - characteristics, efficacy and regulatory aspects of an established treatment of iron deficiency and iron-deficiency anemia in a broad range of therapeutic areas. | 2014 | Expert Opin Pharmacother | pmid:25186219 |
Shiue E et al. | Improving product yields on D-glucose in Escherichia coli via knockout of pgi and zwf and feeding of supplemental carbon sources. | 2015 | Biotechnol. Bioeng. | pmid:25258165 |
Abou-Issa H et al. | Chemotherapeutic evaluation of glucarate and N-(4-hydroxyphenyl)retinamide alone and in combination in the rat mammary tumor model. | 1989 | J. Natl. Cancer Inst. | pmid:2531231 |
pmid:25315985 | ||||
pmid:25326244 | ||||
pmid:25381611 |