Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Pai AB et al. | Effect of intravenous iron supplementation on hepatic cytochrome P450 3A4 activity in hemodialysis patients: a prospective, open-label study. | 2007 | Clin Ther | pmid:18201586 |
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Watanabe S et al. | alpha-ketoglutaric semialdehyde dehydrogenase isozymes involved in metabolic pathways of D-glucarate, D-galactarate, and hydroxy-L-proline. Molecular and metabolic convergent evolution. | 2007 | J. Biol. Chem. | pmid:17202142 |
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GarcÃa-Erce JA et al. | Perioperative intravenous iron preserves iron stores and may hasten the recovery from post-operative anaemia after knee replacement surgery. | 2006 | Transfus Med | pmid:16999756 |
Carlini RG et al. | Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro. | 2006 | Nephrol. Dial. Transplant. | pmid:16957011 |
Agarwal R | Is i.v. iron really superior in CKD patients not on dialysis? | 2006 | Kidney Int. | pmid:16957750 |
Coletta AP et al. | Clinical trials update from the European Society of Cardiology heart failure meeting: TNT subgroup analysis, darbepoetin alfa, FERRIC-HF and KW-3902. | 2006 | Eur. J. Heart Fail. | pmid:16887387 |
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Sirken G et al. | Association of different intravenous iron preparations with risk of bacteremia in maintenance hemodialysis patients. | 2006 | Clin. Nephrol. | pmid:17140164 |
Breborowicz A et al. | Iron sucrose induced morphological and functional changes in the rat kidney. | 2006 | Transl Res | pmid:17145571 |
Schiesser D et al. | Weekly low-dose treatment with intravenous iron sucrose maintains iron status and decreases epoetin requirement in iron-replete haemodialysis patients. | 2006 | Nephrol. Dial. Transplant. | pmid:16891647 |
Sudan C et al. | Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants. | 2006 | Planta | pmid:16652220 |
Koutroubakis IE et al. | Effectiveness of darbepoetin-alfa in combination with intravenous iron sucrose in patients with inflammatory bowel disease and refractory anaemia: a pilot study. | 2006 | Eur J Gastroenterol Hepatol | pmid:16538115 |
Guz G et al. | Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients. | 2006 | Nephrol. Dial. Transplant. | pmid:16762960 |
Barton Pai A et al. | Non-transferrin-bound iron is associated with enhanced Staphylococcus aureus growth in hemodialysis patients receiving intravenous iron sucrose. | 2006 | Am. J. Nephrol. | pmid:16809897 |
Muñoz M et al. | Role of parenteral iron in transfusion requirements after total hip replacement. A pilot study. | 2006 | Transfus Med | pmid:16623920 |
Bhandal N and Russell R | Intravenous versus oral iron therapy for postpartum anaemia. | 2006 | BJOG | pmid:17004982 |
Agarwal R | Proinflammatory effects of iron sucrose in chronic kidney disease. | 2006 | Kidney Int. | pmid:16609688 |
Brown SD et al. | A gold standard set of mechanistically diverse enzyme superfamilies. | 2006 | Genome Biol. | pmid:16507141 |
Ranfaing E | [Treatments of the martial deficiencies: preparations available in France]. | 2006 | Nephrol. Ther. | pmid:17373280 |
Singh H et al. | Effect of intravenous iron sucrose in peritoneal dialysis patients who receive erythropoiesis-stimulating agents for anemia: a randomized, controlled trial. | 2006 | Clin J Am Soc Nephrol | pmid:17699248 |
Bishu K and Agarwal R | Acute injury with intravenous iron and concerns regarding long-term safety. | 2006 | Clin J Am Soc Nephrol | pmid:17699372 |
Zager RA | Parenteral iron compounds: potent oxidants but mainstays of anemia management in chronic renal disease. | 2006 | Clin J Am Soc Nephrol | pmid:17699373 |
Karkouti K et al. | Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia. | 2006 | Can J Anaesth | pmid:16371604 |
Zheng H et al. | Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects. | 2006 | Kidney Int. | pmid:16395269 |
Johnson G et al. | (99m)Tc-glucarate imaging for the early detection of infarct in partially reperfused canine myocardium. | 2006 | Eur. J. Nucl. Med. Mol. Imaging | pmid:16237571 |
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Pecharki GD et al. | Effect of sucrose containing iron (II) on dental biofilm and enamel demineralization in situ. | 2005 Mar-Apr | Caries Res. | pmid:15741724 |
Al-Mueilo SH | Beneficial effects of maintenance intravenous iron saccharate in hemodialysis patients. | 2005 Apr-Jun | Saudi J Kidney Dis Transpl | pmid:18202490 |
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Sanai T et al. | Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats. | 2005 | J. Lab. Clin. Med. | pmid:16025088 |
Macdougall IC and Roche A | Administration of intravenous iron sucrose as a 2-minute push to CKD patients: a prospective evaluation of 2,297 injections. | 2005 | Am. J. Kidney Dis. | pmid:16112047 |
Perek N et al. | MRP-1 protein expression and glutathione content of in vitro tumor cell lines derived from human glioma carcinoma U-87-MG do not interact with 99mTc-glucarate uptake. | 2005 | Cancer Biother. Radiopharm. | pmid:16114987 |
Bontchev RP and Moore RC | Crystal structure and aqueous solubility of ammonium D-glucarate. | 2005 | Carbohydr. Res. | pmid:16043161 |
Breymann C | Treatment of iron deficiency anaemia in pregnancy and postpartum with special focus on intravenous iron sucrose complex. | 2005 | J Med Assoc Thai | pmid:17718296 |