Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Isnardi V et al. | Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? | 2012 | Nucl. Med. Biol. | pmid:23084044 |
Moretto A and Lotti M | Exposure to toluene increases the urinary excretion of D-glucaric acid. | 1990 | Br J Ind Med | pmid:2310708 |
Froessler B et al. | Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial. | 2013 | J. Matern. Fetal. Neonatal. Med. | pmid:23130909 |
Labadarios D et al. | The effects of chronic drug administration on hepatic enzyme induction and folate metabolism. | 1978 | Br J Clin Pharmacol | pmid:23138 |
Bhattacharya S et al. | The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats. | 2013 | Food Funct | pmid:23138840 |
pmid:23166216 | ||||
Devasenapathy N et al. | Is intravenous iron sucrose the treatment of choice for pregnant anemic women? | 2013 | J. Obstet. Gynaecol. Res. | pmid:23167561 |
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Lee ES et al. | Comparison of adverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. | 2013 | Curr Med Res Opin | pmid:23252876 |
Bhattacharya S et al. | D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23261973 |
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pmid:23316876 | ||||
Moore KL et al. | Uncommon adverse effect of a common medication. | 2013 | Tidsskr. Nor. Laegeforen. | pmid:23344600 |
Araki T et al. | Clinical efficacy of two forms of intravenous iron--saccharated ferric oxide and cideferron--for iron deficiency anemia. | 2012 | Pharmazie | pmid:23346769 |
Newman MA et al. | Biological monitoring screening of patients provided antineoplastic drugs including adriamycin, cyclophosphamide, 5-fluorouracil, methotrexate, and vincristine. | 1990 | Cancer Res. | pmid:2334930 |
pmid:23364652 | ||||
Basora M et al. | Optimizing preoperative haemoglobin with intravenous iron. | 2013 | Br J Anaesth | pmid:23404979 |
Dwivedi C et al. | Effect of calcium glucarate on beta-glucuronidase activity and glucarate content of certain vegetables and fruits. | 1990 | Biochem. Med. Metab. Biol. | pmid:2346674 |
Yamamoto S et al. | Iatrogenic osteomalacia: report of two cases. | 2013 | J. UOEH | pmid:23475021 |
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Mishra A et al. | Fatal anaphylactic reaction to iron sucrose in pregnancy. | 2013 Jan-Feb | Indian J Pharmacol | pmid:23543624 |
Douard V et al. | Excessive fructose intake causes 1,25-(OH)(2)D(3)-dependent inhibition of intestinal and renal calcium transport in growing rats. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23571713 |
Ho YD and Ho KJ | Biliary D-glucaric acid: its quantitation and preventive role in gallstone formation. | 1990 | Scand. J. Gastroenterol. | pmid:2359994 |
Munoz C et al. | Klotho sensitivity of the hERG channel. | 2013 | FEBS Lett. | pmid:23603386 |
Bespalov VG and Aleksandrov VA | [Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors]. | 2012 | Vopr Onkol | pmid:23607211 |
Lynn S and McDaniel J | Managing severe anemia when the patient is a Jehovah's Witness. | 2013 | JAAPA | pmid:23610833 |
Elford P et al. | Biodistribution and predictive hepatic gene expression of intravenous iron sucrose. | 2013 Nov-Dec | J Pharmacol Toxicol Methods | pmid:23624021 |
Biggar P and Hahn KM | [Importance of the different i.v. iron generations for everyday medical practice]. | 2013 | MMW Fortschr Med | pmid:23678667 |
Beck-da-Silva L et al. | IRON-HF study: a randomized trial to assess the effects of iron in heart failure patients with anemia. | 2013 | Int. J. Cardiol. | pmid:23680589 |
pmid:23681275 | ||||
Barot BS et al. | Physicochemical and structural characterization of iron-sucrose formulations: a comparative study. | 2014 | Pharm Dev Technol | pmid:23701359 |
Janus N et al. | Administration of intravenous iron complexes on implantable central venous access port in cancer patients in France: the FERPAC survey. | 2013 | Support Care Cancer | pmid:23715817 |
Wang Y et al. | Hepatoprotective effects of kombucha tea: identification of functional strains and quantification of functional components. | 2014 | J. Sci. Food Agric. | pmid:23716136 |
Potthoff SA and Münch HG | [Safety aspects of parenteral iron supplementation therapies in patients with chronic kidney disease]. | 2013 | Dtsch. Med. Wochenschr. | pmid:23737117 |
GarcÃa Erce JA et al. | [Thoughts about the usefulness of the preoperatory administration of intravenous iron in hip fracture surgery]. | 2013 | Med Clin (Barc) | pmid:23790583 |
Kowalczyk MC et al. | Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice. | 2013 | Int. J. Oncol. | pmid:23835587 |
Galanopoulou P et al. | Effect of enzyme induction on bioavailability of hetacillin in patients treated with anticonvulsants and chlorpromazine. | 1990 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:2384113 |
Beguin Y et al. | Darbepoetin-alfa and intravenous iron administration after autologous hematopoietic stem cell transplantation: a prospective multicenter randomized trial. | 2013 | Am. J. Hematol. | pmid:23873823 |
pmid:23890881 | ||||
Contreras C et al. | Comparative study of the oral absorption of microencapsulated ferric saccharate and ferrous sulfate in humans. | 2014 | Eur J Nutr | pmid:23892521 |
pmid:23895304 | ||||
Tian B et al. | Predicting enzyme-substrate specificity with QM/MM methods: a case study of the stereospecificity of (D)-glucarate dehydratase. | 2013 | Biochemistry | pmid:23901785 |
Giger M and Achermann R | [Iron substitution in outpatients in Switzerland: Increase of costs associated with intravenous administration]. | 2013 | Z Evid Fortbild Qual Gesundhwes | pmid:23916272 |
Latham AN | Effect of in vitro changes in urinary pH on the enzymatic measurement and daily variation in excretion of D-glucaric acid. | 1975 | J. Pharm. Pharmacol. | pmid:239180 |
Beck-da-Silva L et al. | Iron therapy in patients with heart failure. A straight shot. | 2013 | Int. J. Cardiol. | pmid:23931974 |
Roots I et al. | Comparison of methods to study enzyme induction in man. | 1975 | Adv. Exp. Med. Biol. | pmid:239546 |
Onken JE et al. | Ferric carboxymaltose in patients with iron-deficiency anemia and impaired renal function: the REPAIR-IDA trial. | 2014 | Nephrol. Dial. Transplant. | pmid:23963731 |
Grim K et al. | Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. | 2013 | Sleep Med. | pmid:23993871 |
Vadasz D et al. | Intravenous iron sucrose for restless legs syndrome in pregnant women with low serum ferritin. | 2013 | Sleep Med. | pmid:24012019 |