Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid:15180183 | ||||
pmid:15160289 | ||||
Scheiber-Mojdehkar B et al. | Non-transferrin-bound iron in the serum of hemodialysis patients who receive ferric saccharate: no correlation to peroxide generation. | 2004 | J. Am. Soc. Nephrol. | pmid:15153577 |
Hanausek M et al. | Modulation of biomarkers during chemoprevention of mouse lung tumorigenesis by D-glucarate. | 2004 | Chest | pmid:15136473 |
Walaszek Z et al. | Mechanisms of lung cancer chemoprevention by D-glucarate. | 2004 | Chest | pmid:15136472 |
Koller WC et al. | Metabolism of glucurolactone to glucarate in Parkinson's disease. | 1992 | Neurology | pmid:1513472 |
Silverstein SB and Rodgers GM | Parenteral iron therapy options. | 2004 | Am. J. Hematol. | pmid:15114602 |
Okada DR et al. | Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate. | 2004 | J. Nucl. Med. | pmid:15073263 |
pmid:15050885 | ||||
Hanausek M et al. | Detoxifying cancer causing agents to prevent cancer. | 2003 | Integr Cancer Ther | pmid:15035900 |
Silverberg D et al. | The use of androgens in anaemia resistant to erythropoietin and i.v. iron in patients with heart and renal failure. | 2004 | Nephrol. Dial. Transplant. | pmid:15031380 |
Lakatos A et al. | AlIII ion complexes of saccharic acid and mucic acid: a solution and solid-state study. | 2004 | Chemistry | pmid:15007818 |
Charytan C et al. | Safety of iron sucrose in hemodialysis patients intolerant to other parenteral iron products. | 2004 | Nephron Clin Pract | pmid:14988600 |
Gupta KP and Singh J | Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin. | 2004 | Toxicol. Sci. | pmid:14976333 |
WHITE LP et al. | The immediate hematologic effects of intravenous saccharated iron oxide. | 1952 | Blood | pmid:14953947 |
LEVVY GA | The inhibition of beta-glucuronidase by derivatives of saccharic acid. | 1952 | Biochem. J. | pmid:14915974 |
HOLLY RG | Intravenous iron: evaluation of the use of saccharated iron oxide in iron deficiency states in obstetrics and gynecology. | 1951 | Blood | pmid:14869375 |
CAMERON DG et al. | Some effects of intravenous injections of saccharated iron oxide on serum iron and unsaturated iron binding capacity. | 1951 | Can Med Assoc J | pmid:14792459 |
CAMERON DG et al. | Treatment of iron deficiency anaemia with saccharated iron oxide given by the intravenous route. | 1951 | Can Med Assoc J | pmid:14792458 |
pmid:14767009 | ||||
Manley HJ and Grabe DW | Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitro study. | 2004 | BMC Nephrol | pmid:14718064 |
Tutor-Crespo MJ et al. | Assessment of copper status in epileptic patients treated with anticonvulsant drugs by measuring the specific oxidase activity of ceruloplasmin. | 2003 | Epilepsy Res. | pmid:14642999 |
Breborowicz M et al. | Effect of iron sucrose on human peritoneal mesothelial cells. | 2003 | Eur. J. Clin. Invest. | pmid:14636286 |
Folkert VW | Intravenous iron therapy in chronic kidney disease and peritoneal dialysis patients. | 2003 | Nephrol Nurs J | pmid:14621635 |
Danielson BG and Beshara S | Pharmacokinetics and utilization of iron sucrose. | 2003 | Am. J. Kidney Dis. | pmid:14582057 |
Geisser P | Reactivity of iron compounds. | 2003 | Am. J. Kidney Dis. | pmid:14582056 |
Verma P et al. | Decolorization of synthetic dyes using a copper complex with glucaric acid. | 2004 | Chemosphere | pmid:14575741 |
Mukhin IV and Nikolenko VIu | [Experimental systemic enzyme therapy of gouty and primary glomerulonephritis]. | 2003 Jul-Aug | Eksp Klin Farmakol | pmid:14558349 |
Colfer M | Achieving optimal patient outcomes with intravenous iron. | 2003 | Nephrol Nurs J | pmid:14533524 |
Blaustein DA et al. | The safety and efficacy of an accelerated iron sucrose dosing regimen in patients with chronic kidney disease. | 2003 | Kidney Int. Suppl. | pmid:14531777 |
Séronie-Vivien S et al. | Epoetin alfa and intravenous iron sucrose to treat severe anemia in a patient with chronic radiation enteropathy: a case report. | 2003 | Med. Oncol. | pmid:14514981 |
Ohtani H et al. | Comparison of technetium-99m-glucarate and thallium-201 for the identification of acute myocardial infarction in rats. | 1992 | J. Nucl. Med. | pmid:1432160 |
pmid:14089452 | ||||
Herzberg M et al. | D-Glucaric acid and gamma-glutamyltransferase as indices of hepatic enzyme induction in pregnancy. | 1977 | Clin. Chem. | pmid:13946 |
Abou-Issa H et al. | Antitumour synergism between non-toxic dietary combinations of isotretinoin and glucarate. | 1992 | Eur. J. Cancer | pmid:1388036 |
RICHTER GW | Intranuclear aggregates of ferritin in liver cells of mice treated with saccharated iron oxide. Their possible relation to nuclear protein synthesis. | 1961 | J Biophys Biochem Cytol | pmid:13741388 |
RICHTER GW | The cellular transformation of injected colloidal iron complexes into ferritin and hemosiderin in experimental animals; a study with the aid of electron microscopy. | 1959 | J. Exp. Med. | pmid:13620849 |
Pistelli A et al. | [Contribution of glutathione to detoxification in alcoholism. Biochemical-clinical studies]. | 1992 | Clin Ter | pmid:1358498 |
BOYLAND E et al. | Enzyme activity in relation to cancer: inhibition of urinary beta-glucuronidase of patients with cancer of the bladder by oral administration of 1:4-saccharolactone and related compounds. | 1957 | Br. J. Cancer | pmid:13510516 |
Pietrantonio AM et al. | [Urinary measurement of D-glucaric acid in operating room personnel in the Modena USL 16 hospitals]. | 1992 Jan-Nov | G Ital Med Lav | pmid:1345728 |
ELLIS JT | Glomerular lesions and the nephrotic syndrome in rabbits given saccharated iron oxide intravenously; with special reference to the part played by intracapillary precipitates in the pathogenesis of the lesions. | 1956 | J. Exp. Med. | pmid:13278460 |
DEVOE RW and MOSES LE | Iron therapy in pregnancy; a comparative study of various modes. | 1954 | Calif Med | pmid:13209356 |
NISSIM JA | Toxic reactions after intravenous saccharated iron oxide in man; suggestions for improved preparations. | 1954 | Br Med J | pmid:13115719 |
DESHMUKH PL | Intravenous iron therapy with saccharated iron oxide. | 1952 | Ind Med Gaz | pmid:12990194 |
pmid:12942420 | ||||
Apostoli P et al. | Relationship between PCBs in blood and D-glucaric acid in urine. | 2003 | Toxicol. Lett. | pmid:12919720 |
Deicher R et al. | High-dose parenteral iron sucrose depresses neutrophil intracellular killing capacity. | 2003 | Kidney Int. | pmid:12846772 |
Silverberg DS et al. | Effect of correction of anemia with erythropoietin and intravenous iron in resistant heart failure in octogenarians. | 2003 | Isr. Med. Assoc. J. | pmid:12811950 |
pmid:12787877 | ||||
pmid:12778887 |