Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sricholpech M et al. | Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. | 2012 | J. Biol. Chem. | pmid:22573318 |
Wyffels L et al. | Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate. | 2012 | Mol Imaging | pmid:22554483 |
Monsénégo J et al. | Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. | 2012 | J. Hepatol. | pmid:22037024 |
Ozkurt S et al. | Acute and subacute effects of EV iron sucrose on endothelial functions in hemodialysis patients. | 2012 | Ren Fail | pmid:22017464 |
Toblli JE et al. | Comparison of oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model. | 2012 | Inflamm Allergy Drug Targets | pmid:22309085 |
Stachowska-Pietka J et al. | Computer simulations of osmotic ultrafiltration and small-solute transport in peritoneal dialysis: a spatially distributed approach. | 2012 | Am. J. Physiol. Renal Physiol. | pmid:22301624 |
Smith AA et al. | The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. | 2012 | PLoS Comput. Biol. | pmid:22693442 |
De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
Ceretta LB et al. | Increased oxidative stress and imbalance in antioxidant enzymes in the brains of alloxan-induced diabetic rats. | 2012 | Exp Diabetes Res | pmid:22645603 |
Bidossi A et al. | A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. | 2012 | PLoS ONE | pmid:22428019 |
Galutira PJ and Del Rio M | Understanding renal posttransplantation anemia in the pediatric population. | 2012 | Pediatr. Nephrol. | pmid:22086345 |
Ernst MC et al. | Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. | 2012 | Endocrinology | pmid:22186410 |
Kamanna VS et al. | Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. | 2012 | Am. J. Nephrol. | pmid:22212390 |
Stein J et al. | Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. | 2012 | Curr Med Res Opin | pmid:22181342 |
Rashid K et al. | Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. | 2012 | Free Radic. Res. | pmid:22239106 |
Ichii H et al. | Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. | 2012 | Am. J. Nephrol. | pmid:22722756 |
Pfenniger A et al. | Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. | 2012 | J Perinat Med | pmid:22752771 |
da Silva Krause M et al. | Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. | 2012 | J. Endocrinol. | pmid:22761278 |
Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
Conner TA et al. | Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. | 2012 | Biometals | pmid:22706571 |
Walters KR et al. | Methamphetamine causes anorexia in Drosophila melanogaster, exhausting metabolic reserves and contributing to mortality. | 2012 | J Toxicol Sci | pmid:22863857 |
Bespalov VG and Aleksandrov VA | [Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors]. | 2012 | Vopr Onkol | pmid:23607211 |
Araki T et al. | Clinical efficacy of two forms of intravenous iron--saccharated ferric oxide and cideferron--for iron deficiency anemia. | 2012 | Pharmazie | pmid:23346769 |
Isnardi V et al. | Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? | 2012 | Nucl. Med. Biol. | pmid:23084044 |
Xia B et al. | A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. | 2012 | Mol. Pharm. | pmid:23033922 |
Kumbasar A et al. | The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. | 2012 Sep-Oct | J. Nephrol. | pmid:22307439 |
Reinisch W et al. | State of the iron: how to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease. | 2013 | J Crohns Colitis | pmid:22917870 |
Kochhar PK et al. | Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial. | 2013 | J. Obstet. Gynaecol. Res. | pmid:22925176 |
Lynn S and McDaniel J | Managing severe anemia when the patient is a Jehovah's Witness. | 2013 | JAAPA | pmid:23610833 |
Biggar P and Hahn KM | [Importance of the different i.v. iron generations for everyday medical practice]. | 2013 | MMW Fortschr Med | pmid:23678667 |
Beck-da-Silva L et al. | IRON-HF study: a randomized trial to assess the effects of iron in heart failure patients with anemia. | 2013 | Int. J. Cardiol. | pmid:23680589 |
Goldstein SL et al. | Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial. | 2013 | Am. J. Kidney Dis. | pmid:23245582 |
Blanco Rubio N et al. | [Preoperative intravenous iron as a strategy for blood saving in surgery for hip fracture]. | 2013 | Med Clin (Barc) | pmid:23246172 |
Lee ES et al. | Comparison of adverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. | 2013 | Curr Med Res Opin | pmid:23252876 |
Bhattacharya S et al. | D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23261973 |
Moore KL et al. | Uncommon adverse effect of a common medication. | 2013 | Tidsskr. Nor. Laegeforen. | pmid:23344600 |
Froessler B et al. | Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial. | 2013 | J. Matern. Fetal. Neonatal. Med. | pmid:23130909 |
Bhattacharya S et al. | The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats. | 2013 | Food Funct | pmid:23138840 |
Devasenapathy N et al. | Is intravenous iron sucrose the treatment of choice for pregnant anemic women? | 2013 | J. Obstet. Gynaecol. Res. | pmid:23167561 |
Wilson PD et al. | An analysis of the health service efficiency and patient experience with two different intravenous iron preparations in a UK anaemia clinic. | 2013 | J Med Econ | pmid:22989163 |
Douard V et al. | Excessive fructose intake causes 1,25-(OH)(2)D(3)-dependent inhibition of intestinal and renal calcium transport in growing rats. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23571713 |
Yang Z et al. | Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity. | 2013 | Infect. Immun. | pmid:23509143 |
Kalaivani K | Use of intravenous iron sucrose for treatment of anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056552 |
Kriplani A et al. | Intravenous iron sucrose therapy for moderate to severe anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056559 |
Michigami T | [Updates on rickets and osteomalacia: FGF23-mediated hypophosphatemic rickets/osteomalacia]. | 2013 | Clin Calcium | pmid:24076640 |
Italia K et al. | Hydroxyurea could be a good clinically relevant iron chelator. | 2013 | PLoS ONE | pmid:24349400 |
Grim K et al. | Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. | 2013 | Sleep Med. | pmid:23993871 |
Athibovonsuk P et al. | Prevention of blood transfusion with intravenous iron in gynecologic cancer patients receiving platinum-based chemotherapy. | 2013 | Gynecol. Oncol. | pmid:24099839 |
Ferumoxytol: an intravenous iron, riskier than iron sucrose. | 2013 | Prescrire Int | pmid:24171212 | |
Rowlands M et al. | The effect of intravenous iron on postoperative transfusion requirements in hip fracture patients: study protocol for a randomized controlled trial. | 2013 | Trials | pmid:24015990 |