Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Anemia, Iron-Deficiency D018798 6 associated lipids
Thrombophlebitis D013924 6 associated lipids
Blood Loss, Surgical D016063 6 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Leprosy D007918 8 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Hearing Disorders D006311 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Vindal V et al. GntR family of regulators in Mycobacterium smegmatis: a sequence and structure based characterization. 2007 BMC Genomics pmid:17714599
Francis GS and Kanderian A Anemia and heart failure a new pathway? 2007 J. Am. Coll. Cardiol. pmid:17950148
Beck-da-Silva L et al. Rationale and design of the IRON-HF study: a randomized trial to assess the effects of iron supplementation in heart failure patients with anemia. 2007 J. Card. Fail. pmid:17338998
Sane R et al. Safe administration of iron sucrose in a patient with a previous hypersensitivity reaction to ferric gluconate. 2007 Pharmacotherapy pmid:17381390
Breymann C et al. Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex. 2007 J Perinat Med pmid:17302514
Breborowicz A et al. Peritoneal effects of intravenous iron sucrose administration in rats. 2007 Transl Res pmid:17543848
Sav T et al. Is there a difference between the allergic potencies of the iron sucrose and low molecular weight iron dextran? 2007 Ren Fail pmid:17497463
Pai AB et al. Comparison of oxidative stress markers after intravenous administration of iron dextran, sodium ferric gluconate, and iron sucrose in patients undergoing hemodialysis. 2007 Pharmacotherapy pmid:17316146
Vikrant S Optimum dosage regimen for iron sucrose. 2007 Kidney Int. pmid:17625585
Reed J et al. The safety of intravenous iron sucrose use in the elderly patient. 2007 Consult Pharm pmid:17658969
Auerbach M and Rodgers GM Intravenous iron. 2007 N. Engl. J. Med. pmid:17611217
Agarwal R et al. Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease. 2007 Kidney Int. pmid:17622274
Marsillach J et al. Administration of exogenous erythropoietin beta affects lipid peroxidation and serum paraoxonase-1 activity and concentration in predialysis patients with chronic renal disease and anaemia. 2007 Clin. Exp. Pharmacol. Physiol. pmid:17324148
Thomas J and Martinez A Blood conservation in the critically ill. 2007 Am J Health Syst Pharm pmid:17687066
Malindretos P et al. Slow intravenous iron administration does not aggravate oxidative stress and inflammatory biomarkers during hemodialysis: a comparative study between iron sucrose and iron dextran. 2007 Am. J. Nephrol. pmid:17804904
Davey CL et al. Esterification of select polyols with D-glucaric acid as model reactions for esterification of starch. 2006 Carbohydr. Res. pmid:16973136
Bolger AP et al. Intravenous iron alone for the treatment of anemia in patients with chronic heart failure. 2006 J. Am. Coll. Cardiol. pmid:16979010
Kato M et al. Tetranuclear copper(II) complexes bridged by alpha-D-glucose-1-phosphate and incorporation of sugar acids through the Cu4 core structural changes. 2006 Inorg Chem pmid:16903719
García-Erce JA et al. Perioperative intravenous iron preserves iron stores and may hasten the recovery from post-operative anaemia after knee replacement surgery. 2006 Transfus Med pmid:16999756
Carlini RG et al. Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro. 2006 Nephrol. Dial. Transplant. pmid:16957011
Agarwal R Is i.v. iron really superior in CKD patients not on dialysis? 2006 Kidney Int. pmid:16957750
Coletta AP et al. Clinical trials update from the European Society of Cardiology heart failure meeting: TNT subgroup analysis, darbepoetin alfa, FERRIC-HF and KW-3902. 2006 Eur. J. Heart Fail. pmid:16887387
Eiselt J et al. The effect of intravenous iron on oxidative stress in hemodialysis patients at various levels of vitamin C. 2006 Blood Purif. pmid:17077626
Sirken G et al. Association of different intravenous iron preparations with risk of bacteremia in maintenance hemodialysis patients. 2006 Clin. Nephrol. pmid:17140164
Breborowicz A et al. Iron sucrose induced morphological and functional changes in the rat kidney. 2006 Transl Res pmid:17145571
Schiesser D et al. Weekly low-dose treatment with intravenous iron sucrose maintains iron status and decreases epoetin requirement in iron-replete haemodialysis patients. 2006 Nephrol. Dial. Transplant. pmid:16891647
Sudan C et al. Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants. 2006 Planta pmid:16652220
Koutroubakis IE et al. Effectiveness of darbepoetin-alfa in combination with intravenous iron sucrose in patients with inflammatory bowel disease and refractory anaemia: a pilot study. 2006 Eur J Gastroenterol Hepatol pmid:16538115
Guz G et al. Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients. 2006 Nephrol. Dial. Transplant. pmid:16762960
Barton Pai A et al. Non-transferrin-bound iron is associated with enhanced Staphylococcus aureus growth in hemodialysis patients receiving intravenous iron sucrose. 2006 Am. J. Nephrol. pmid:16809897
Muñoz M et al. Role of parenteral iron in transfusion requirements after total hip replacement. A pilot study. 2006 Transfus Med pmid:16623920
Bhandal N and Russell R Intravenous versus oral iron therapy for postpartum anaemia. 2006 BJOG pmid:17004982
Agarwal R Proinflammatory effects of iron sucrose in chronic kidney disease. 2006 Kidney Int. pmid:16609688
Brown SD et al. A gold standard set of mechanistically diverse enzyme superfamilies. 2006 Genome Biol. pmid:16507141
Ranfaing E [Treatments of the martial deficiencies: preparations available in France]. 2006 Nephrol. Ther. pmid:17373280
Singh H et al. Effect of intravenous iron sucrose in peritoneal dialysis patients who receive erythropoiesis-stimulating agents for anemia: a randomized, controlled trial. 2006 Clin J Am Soc Nephrol pmid:17699248
Bishu K and Agarwal R Acute injury with intravenous iron and concerns regarding long-term safety. 2006 Clin J Am Soc Nephrol pmid:17699372
Zager RA Parenteral iron compounds: potent oxidants but mainstays of anemia management in chronic renal disease. 2006 Clin J Am Soc Nephrol pmid:17699373
Karkouti K et al. Intravenous iron and recombinant erythropoietin for the treatment of postoperative anemia. 2006 Can J Anaesth pmid:16371604
Zheng H et al. Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects. 2006 Kidney Int. pmid:16395269
Johnson G et al. (99m)Tc-glucarate imaging for the early detection of infarct in partially reperfused canine myocardium. 2006 Eur. J. Nucl. Med. Mol. Imaging pmid:16237571
Cançado RD et al. [Evaluation of the efficacy of intravenous iron III-hydroxide saccharate for treating adult patients with iron deficiency anemia]. 2005 Nov-Dec Rev Assoc Med Bras (1992) pmid:16444338
Pecharki GD et al. Effect of sucrose containing iron (II) on dental biofilm and enamel demineralization in situ. 2005 Mar-Apr Caries Res. pmid:15741724
Al-Mueilo SH Beneficial effects of maintenance intravenous iron saccharate in hemodialysis patients. 2005 Apr-Jun Saudi J Kidney Dis Transpl pmid:18202490
Agarwal R Ironing out the mystery of nephrotoxicity of parenteral iron. 2005 J. Lab. Clin. Med. pmid:16025083
Sanai T et al. Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats. 2005 J. Lab. Clin. Med. pmid:16025088
Macdougall IC and Roche A Administration of intravenous iron sucrose as a 2-minute push to CKD patients: a prospective evaluation of 2,297 injections. 2005 Am. J. Kidney Dis. pmid:16112047
Perek N et al. MRP-1 protein expression and glutathione content of in vitro tumor cell lines derived from human glioma carcinoma U-87-MG do not interact with 99mTc-glucarate uptake. 2005 Cancer Biother. Radiopharm. pmid:16114987
Bontchev RP and Moore RC Crystal structure and aqueous solubility of ammonium D-glucarate. 2005 Carbohydr. Res. pmid:16043161
Wood DM et al. Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child. 2005 Ther Drug Monit pmid:16044093
Sheashaa H et al. Parenteral iron therapy in treatment of anemia in end-stage renal disease patients: a comparative study between iron saccharate and gluconate. 2005 Nephron Clin Pract pmid:15692217
Keven K et al. Combination of intravenous iron sucrose and ascorbic acid in hemodialysis patients. 2005 Kidney Int. pmid:15954940
Anbu AT et al. Low incidence of adverse events following 90-minute and 3-minute infusions of intravenous iron sucrose in children on erythropoietin. 2005 Acta Paediatr. pmid:16431410
Zager RA Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy. 2005 Kidney Int. pmid:16164630
Erichsen K et al. Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. 2005 Scand. J. Gastroenterol. pmid:16165718
St Peter WL et al. Trends in intravenous iron use among dialysis patients in the United States (1994-2002). 2005 Am. J. Kidney Dis. pmid:16183420
Ayotte P et al. Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. 2005 Environ. Health Perspect. pmid:16203240
Liu Y and Reineke TM Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery. 2005 J. Am. Chem. Soc. pmid:15740138
Georgopoulos D et al. Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317]. 2005 Crit Care pmid:16277712
Laman CA et al. Parenteral iron therapy: a single institution's experience over a 5-year period. 2005 J Natl Compr Canc Netw pmid:16316614
Strolin Benedetti M et al. Induction of endogenous pathways by antiepileptics and clinical implications. 2005 Fundam Clin Pharmacol pmid:16176329
Breymann C Treatment of iron deficiency anaemia in pregnancy and postpartum with special focus on intravenous iron sucrose complex. 2005 J Med Assoc Thai pmid:17718296
Cuenca J et al. Role of parenteral iron in the management of anaemia in the elderly patient undergoing displaced subcapital hip fracture repair: preliminary data. 2005 Arch Orthop Trauma Surg pmid:15789233
Tutor-Crespo MJ et al. Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects. 2005 J. Pharmacol. Sci. pmid:16314692
Schaller G et al. Intravenous iron increases labile serum iron but does not impair forearm blood flow reactivity in dialysis patients. 2005 Kidney Int. pmid:16316358
Van Wyck DB et al. A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. 2005 Kidney Int. pmid:16316362
Anemia during pregnancy and in the postpartum: intravenous iron therapy revisited. 2005 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:16360535
Govan AD and Scott JM Intravenous iron in the treatment of anemia of pregnancy. 1949. 2005 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:16360540
Ozdemir A et al. Relationship between iron replacement and hepatic functions in hepatitis C virus-positive chronic haemodialysis patients. 2005 Nephrology (Carlton) pmid:16221090
Spiegel K et al. Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. 2005 J. Appl. Physiol. pmid:16227462
Aime S et al. para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents. 2005 Org. Biomol. Chem. pmid:16240012
Schröder O et al. Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease--a randomized, controlled, open-label, multicenter study. 2005 Am. J. Gastroenterol. pmid:16279906
Sengölge G et al. Intravenous iron therapy: well-tolerated, yet not harmless. 2005 Eur. J. Clin. Invest. pmid:16281958
Agarwal R On the nature of proteinuria with acute renal injury in patients with chronic kidney disease. 2005 Am. J. Physiol. Renal Physiol. pmid:15467003
Leijn E et al. Intravenous iron supplementation in children on hemodialysis. 2004 May-Jun J. Nephrol. pmid:15365964
Verma P et al. Decolorization of synthetic dyes using a copper complex with glucaric acid. 2004 Chemosphere pmid:14575741
Cuenca J et al. Patients with pertrochanteric hip fracture may benefit from preoperative intravenous iron therapy: a pilot study. 2004 Transfusion pmid:15383017
Schwenk MH and Blaustein DA Rapid, high-dose intravenous iron sucrose therapy in 2 Jehovah's Witness patients with severe anemia, iron deficiency and chronic kidney disease. 2004 Clin. Nephrol. pmid:15356968
Tiranathanagul K et al. Oxidative stress from rapid versus slow intravenous iron replacement in haemodialysis patients. 2004 Nephrology (Carlton) pmid:15363053
McMahon LP et al. Effects of different dialysis membranes on serum concentrations of epoetin alfa, darbepoetin alfa, enoxaparin, and iron sucrose during dialysis. 2004 Am. J. Kidney Dis. pmid:15332224
Schröder O et al. A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding. 2004 Z Gastroenterol pmid:15314711
Tutor-Crespo MJ et al. Possible induction of cholinesterase in epileptic patients treated with anticonvulsant drugs: relationship with lipoprotein levels. 2004 J Clin Pharmacol pmid:15317825
Agarwal R Transferrin saturation with intravenous irons: an in vitro study. 2004 Kidney Int. pmid:15327409
Aronoff GR et al. Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens. 2004 Kidney Int. pmid:15327417
Liu Z et al. 99mTc glucarate high-resolution imaging of drug sensitive and drug resistant human breast cancer xenografts in SCID mice. 2004 Nucl Med Commun pmid:15208499
Liu Y et al. New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells. 2004 J. Am. Chem. Soc. pmid:15198572
Zager RA et al. Parenteral iron nephrotoxicity: potential mechanisms and consequences. 2004 Kidney Int. pmid:15200421
Dornyei A et al. Vanadium(IV,V) complexes of D-saccharic and mucic acids in aqueous solution. 2004 Dalton Trans pmid:15381996
Hanausek M et al. Modulation of biomarkers during chemoprevention of mouse lung tumorigenesis by D-glucarate. 2004 Chest pmid:15136473
Silverstein SB and Rodgers GM Parenteral iron therapy options. 2004 Am. J. Hematol. pmid:15114602
Okada DR et al. Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate. 2004 J. Nucl. Med. pmid:15073263
Manley HJ and Grabe DW Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitro study. 2004 BMC Nephrol pmid:14718064
Tutor-Crespo M et al. Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs. 2004 J Pharm Pharm Sci pmid:15576017
Silverberg D et al. The use of androgens in anaemia resistant to erythropoietin and i.v. iron in patients with heart and renal failure. 2004 Nephrol. Dial. Transplant. pmid:15031380
Liu Z et al. High-resolution imaging with (99m)Tc-glucarate for assessing myocardial injury in rat heart models exposed to different durations of ischemia with reperfusion. 2004 J. Nucl. Med. pmid:15235074
Ogi M et al. [Comparison of intravenous ascorbic acid versus intravenous iron for functional iron deficiency in hemodialysis patients]. 2004 Nihon Jinzo Gakkai Shi pmid:15645737
Guz G et al. Elevated cardiac troponin T in hemodialysis patients receiving more intravenous iron sucrose. 2004 Ren Fail pmid:15600258
Charytan C et al. Safety of iron sucrose in hemodialysis patients intolerant to other parenteral iron products. 2004 Nephron Clin Pract pmid:14988600
Gupta KP and Singh J Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin. 2004 Toxicol. Sci. pmid:14976333
Borawski J et al. Endothelial injury markers with high-dose intravenous iron therapy in renal failure. 2004 Clin. Appl. Thromb. Hemost. pmid:15497030