| MeSH term | MeSH ID | Detail |
|---|---|---|
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Fasciitis | D005208 | 2 associated lipids |
| Femoral Neck Fractures | D005265 | 3 associated lipids |
| Gilbert Disease | D005878 | 2 associated lipids |
| Glucosephosphate Dehydrogenase Deficiency | D005955 | 5 associated lipids |
| Hearing Disorders | D006311 | 10 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hemosiderosis | D006486 | 1 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sricholpech M et al. | Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. | 2012 | J. Biol. Chem. | pmid:22573318 |
| Wyffels L et al. | Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate. | 2012 | Mol Imaging | pmid:22554483 |
| Monsénégo J et al. | Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. | 2012 | J. Hepatol. | pmid:22037024 |
| Smith AA et al. | The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. | 2012 | PLoS Comput. Biol. | pmid:22693442 |
| De Sousa A and Kalra G | Drug therapy of attention deficit hyperactivity disorder: current trends. | 2012 | Mens Sana Monogr | pmid:22654382 |
| Ceretta LB et al. | Increased oxidative stress and imbalance in antioxidant enzymes in the brains of alloxan-induced diabetic rats. | 2012 | Exp Diabetes Res | pmid:22645603 |
| Bidossi A et al. | A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. | 2012 | PLoS ONE | pmid:22428019 |
| Galutira PJ and Del Rio M | Understanding renal posttransplantation anemia in the pediatric population. | 2012 | Pediatr. Nephrol. | pmid:22086345 |
| Ernst MC et al. | Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. | 2012 | Endocrinology | pmid:22186410 |
| Kamanna VS et al. | Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. | 2012 | Am. J. Nephrol. | pmid:22212390 |
| Stein J et al. | Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. | 2012 | Curr Med Res Opin | pmid:22181342 |
| Rashid K et al. | Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. | 2012 | Free Radic. Res. | pmid:22239106 |
| Ichii H et al. | Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. | 2012 | Am. J. Nephrol. | pmid:22722756 |
| Pfenniger A et al. | Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. | 2012 | J Perinat Med | pmid:22752771 |
| da Silva Krause M et al. | Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. | 2012 | J. Endocrinol. | pmid:22761278 |
| Galindo P et al. | Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. | 2012 | PLoS ONE | pmid:22427863 |
| Conner TA et al. | Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. | 2012 | Biometals | pmid:22706571 |
| Walters KR et al. | Methamphetamine causes anorexia in Drosophila melanogaster, exhausting metabolic reserves and contributing to mortality. | 2012 | J Toxicol Sci | pmid:22863857 |
| Isnardi V et al. | Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? | 2012 | Nucl. Med. Biol. | pmid:23084044 |
| Xia B et al. | A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. | 2012 | Mol. Pharm. | pmid:23033922 |
| Kowalczyk M et al. | Ferumoxytol: a new era of iron deficiency anemia treatment for patients with chronic kidney disease. | 2011 Nov-Dec | J. Nephrol. | pmid:21956770 |
| Bhattacharya S et al. | Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. | 2011 Nov-Dec | J. Biochem. Mol. Toxicol. | pmid:21538728 |
| Adhikary L and Acharya S | Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. | 2011 Jul-Sep | JNMA J Nepal Med Assoc | pmid:22922860 |
| Moorani KN and Asim S | Parenteral iron sucrose in iron deficiency anaemia of paediatric chronic kidney disease. | 2011 Jul-Sep | J Ayub Med Coll Abbottabad | pmid:23272434 |
| Yetman AT and Everitt MD | The role of iron deficiency in protein-losing enteropathy following the Fontan procedure. | 2011 Jul-Aug | Congenit Heart Dis | pmid:21392262 |
| Centeno DC et al. | Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. | 2011 | Plant Cell | pmid:21239646 |
| Walther J et al. | Hot transcriptomics. | 2011 | Archaea | pmid:21350598 |
| Denton TT et al. | Characterization of D-glucaric acid using NMR, X-ray crystal structure, and MM3 molecular modeling analyses. | 2011 | Carbohydr. Res. | pmid:22015400 |
| Bhattacharya S et al. | D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21982801 |
| Aspuru K et al. | Optimal management of iron deficiency anemia due to poor dietary intake. | 2011 | Int J Gen Med | pmid:22114518 |
| Toblli JE et al. | Evaluation of toxicity and oxidative stress induced by intravenous iron isomaltoside 1000 in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:22164963 |
| Menendez C et al. | Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed? | 2011 | Mol Nutr Food Res | pmid:22144045 |
| Di Nocera PP et al. | Genome organization of epidemic Acinetobacter baumannii strains. | 2011 | BMC Microbiol. | pmid:21985032 |
| Lv YK et al. | Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-yttriate(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836844 |
| Cheng D et al. | A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. | 2011 | Curr Radiopharm | pmid:22191610 |
| Lv YK et al. | Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-samarate(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836843 |
| Toyokuni S | Mysterious link between iron overload and CDKN2A/2B. | 2011 | J Clin Biochem Nutr | pmid:21297911 |
| Nasir A et al. | Management of iron deficiency anaemia in gynaecological patients at Jinnah Postgraduate Medical Centre, Karachi. | 2011 | J Pak Med Assoc | pmid:22356035 |
| Wada Y et al. | [Case report; A case of FGF23-related hypophosphatemic osteomalacia caused by long-term administration of saccharated ferric oxide]. | 2011 | Nippon Naika Gakkai Zasshi | pmid:22175146 |
| Lawrence MC et al. | Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cells. | 2011 | J. Biol. Chem. | pmid:21059644 |
| Kolodziejczyk J et al. | In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. | 2011 | J. Physiol. Biochem. | pmid:21086198 |
| Vu'o'ng Lê B et al. | New rat models of iron sucrose-induced iron overload. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21685238 |
| Kowalczyk MC et al. | Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors. | 2011 | Oncol. Rep. | pmid:21687956 |
| Evstatiev R et al. | FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease. | 2011 | Gastroenterology | pmid:21699794 |
| Solak Y et al. | Comparison of adverse-event profiles of intravenous low-molecular-weight iron dextran and iron sucrose in peritoneal dialysis patients. | 2011 | Ren Fail | pmid:21401355 |
| Gambini JP et al. | Evaluation of 99mTc-glucarate as a breast cancer imaging agent in a xenograft animal model. | 2011 | Nucl. Med. Biol. | pmid:21315281 |
| Takeda Y et al. | Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients. | 2011 | Am. J. Nephrol. | pmid:21502756 |
| Meier T et al. | Physicochemical and toxicological characterization of a new generic iron sucrose preparation. | 2011 | Arzneimittelforschung | pmid:21428246 |
| Agarwal R et al. | Proteinuria induced by parenteral iron in chronic kidney disease--a comparative randomized controlled trial. | 2011 | Clin J Am Soc Nephrol | pmid:20876669 |
| Auerbach M | Should intravenous iron be upfront therapy for iron deficiency anemia? | 2011 | Pediatr Blood Cancer | pmid:21298731 |
| Crary SE et al. | Intravenous iron sucrose for children with iron deficiency failing to respond to oral iron therapy. | 2011 | Pediatr Blood Cancer | pmid:21298748 |
| Ibert M et al. | Evidence of benzilic rearrangement during the electrochemical oxidation of D-glucose to D-glucaric acid. | 2011 | Carbohydr. Res. | pmid:21269605 |
| Vanderford NL | The role of MafA in regulating cytokine expression in pancreatic beta cells. | 2011 | J. Biol. Chem. | pmid:21239506 |
| Fenwick S and Peebles G | Total dose infusion of intravenous iron in patients with chronic kidney disease receiving haemodialysis. | 2011 | J Ren Care | pmid:21288317 |
| Pai AB et al. | Non-transferrin bound iron, cytokine activation and intracellular reactive oxygen species generation in hemodialysis patients receiving intravenous iron dextran or iron sucrose. | 2011 | Biometals | pmid:21229380 |
| Krafft A and Breymann C | Iron sucrose with and without recombinant erythropoietin for the treatment of severe postpartum anemia: a prospective, randomized, open-label study. | 2011 | J. Obstet. Gynaecol. Res. | pmid:21159035 |
| Stefánsson BV et al. | Acute oxidative stress following intravenous iron injection in patients on chronic hemodialysis: a comparison of iron-sucrose and iron-dextran. | 2011 | Nephron Clin Pract | pmid:21196770 |
| Atalay H et al. | Safety profiles of total dose infusion of low-molecular-weight iron dextran and high-dose iron sucrose in renal patients. | 2011 | Hemodial Int | pmid:21564503 |
| Serrano-Trenas JA et al. | Role of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial. | 2011 | Transfusion | pmid:20630042 |
| Malovrh M et al. | The influence of need-based, continuous, low-dose iron replacement on hemoglobin levels in hemodialysis patients treated with erythropoiesis-stimulating agents. | 2011 | Artif Organs | pmid:20618233 |
| Rottembourg J et al. | Do two intravenous iron sucrose preparations have the same efficacy? | 2011 | Nephrol. Dial. Transplant. | pmid:21355067 |
| Kim Y et al. | Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. | 2011 | Nutr Res | pmid:22118754 |
| Bailie GR et al. | Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. | 2011 | Arzneimittelforschung | pmid:21755809 |
| Gomollón F and Gisbert JP | IBD: Intravenous iron in IBD--what's the best preparation? | 2011 | Nat Rev Gastroenterol Hepatol | pmid:21788975 |
| Bisbe E et al. | A multicentre comparative study on the efficacy of intravenous ferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery. | 2011 | Br J Anaesth | pmid:21841061 |
| Toblli JE et al. | Assessment of the extent of oxidative stress induced by intravenous ferumoxytol, ferric carboxymaltose, iron sucrose and iron dextran in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:21899208 |
| Goggin MM et al. | Analysis of total and transferrin-bound iron in human serum for pharmacokinetic studies of iron-sucrose formulations. | 2011 | Bioanalysis | pmid:21877893 |
| Ruiz JC et al. | Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. | 2011 | PLoS ONE | pmid:21533164 |
| Rodionov DA et al. | Genomic encyclopedia of sugar utilization pathways in the Shewanella genus. | 2010 | BMC Genomics | pmid:20836887 |
| Chaudhuri RR et al. | Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042. | 2010 | PLoS ONE | pmid:20098708 |
| Laidlaw M et al. | Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial. | 2010 | Breast Cancer (Auckl) | pmid:21234288 |
| Lippow SM et al. | Engineering enzyme specificity using computational design of a defined-sequence library. | 2010 | Chem. Biol. | pmid:21168766 |
| Suzuki E et al. | Identification of valproic acid glucuronide hydrolase as a key enzyme for the interaction of valproic acid with carbapenem antibiotics. | 2010 | Drug Metab. Dispos. | pmid:20551238 |
| Hoffman K et al. | Exposure to polyfluoroalkyl chemicals and attention deficit/hyperactivity disorder in U.S. children 12-15 years of age. | 2010 | Environ. Health Perspect. | pmid:20551004 |
| Sienkiewicz-Porzucek A et al. | Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth. | 2010 | Mol Plant | pmid:20035036 |
| Sturm B et al. | In vitro study on the effects of iron sucrose, ferric gluconate and iron dextran on redox-active iron and oxidative stress. | 2010 | Arzneimittelforschung | pmid:20712137 |
| Swarnalatha G et al. | Oxidative stress in hemodialysis patients receiving intravenous iron therapy and the role of N-acetylcysteine in preventing oxidative stress. | 2010 | Saudi J Kidney Dis Transpl | pmid:20814119 |
| Bager P and Dahlerup JF | The health care cost of intravenous iron treatment in IBD patients depends on the economic evaluation perspective. | 2010 | J Crohns Colitis | pmid:21122539 |
| Froessler B and Papendorf D | Intravenous iron sucrose--an effective and attractive modality for perioperative anaemia management. | 2010 | Anaesth Intensive Care | pmid:20865896 |
| Saluk-Juszczak J | A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. | 2010 | Platelets | pmid:20873960 |
| Dangsuwan P and Manchana T | Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy. | 2010 | Gynecol. Oncol. | pmid:20051288 |
| Lajolo C et al. | Calcium glucarate inhibits DMBA-induced oral carcinogenesis in the hamster: histomorphometric evaluation. | 2010 | Anticancer Res. | pmid:20393005 |
| Wu CJ et al. | Comparison of parenteral iron sucrose and ferric chloride during erythropoietin therapy of haemodialysis patients. | 2010 | Nephrology (Carlton) | pmid:20377770 |
| McMahon LP et al. | Maintenance of elevated versus physiological iron indices in non-anaemic patients with chronic kidney disease: a randomized controlled trial. | 2010 | Nephrol. Dial. Transplant. | pmid:19906658 |
| Stancu S et al. | Can the response to iron therapy be predicted in anemic nondialysis patients with chronic kidney disease? | 2010 | Clin J Am Soc Nephrol | pmid:20019121 |
| Rombouts K and Marra F | Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis. | 2010 | Dig Dis | pmid:20460917 |
| Rangel EB et al. | Labile plasma iron generation after intravenous iron is time-dependent and transitory in patients undergoing chronic hemodialysis. | 2010 | Ther Apher Dial | pmid:20438541 |
| Tampi R | Delayed adverse reactions to iron polymaltose and iron sucrose. | 2010 | Intern Med J | pmid:20446963 |
| Garcia-Fernandez N et al. | Randomized clinical trial on acute effects of i.v. iron sucrose during haemodialysis. | 2010 | Nephrology (Carlton) | pmid:20470276 |
| Firoz BF et al. | Eosinophilic fasciitis secondary to intravenous iron infusions. | 2010 | Dermatol. Online J. | pmid:20492822 |
| Gupta A et al. | Response to iron sucrose in dialysis patients sensitive to iron dextran. | 2010 | Saudi J Kidney Dis Transpl | pmid:20587886 |
| Zhang ZW et al. | The plastid hexokinase pHXK: a node of convergence for sugar and plastid signals in Arabidopsis. | 2010 | FEBS Lett. | pmid:20650273 |
| Okada DR et al. | 99mTc-glucarate kinetics differentiate normal, stunned, hibernating, and nonviable myocardium in a perfused rat heart model. | 2010 | Eur. J. Nucl. Med. Mol. Imaging | pmid:20652807 |
| Kell DB | Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. | 2010 | Arch. Toxicol. | pmid:20967426 |
| Chinnappa S and Bhandari S | Influence of intravenous iron therapy on novel markers of iron deficiency. | 2010 | Int J Artif Organs | pmid:20593351 |
| Birgegård G et al. | High incidence of iron depletion and restless leg syndrome (RLS) in regular blood donors: intravenous iron sucrose substitution more effective than oral iron. | 2010 | Vox Sang. | pmid:20598107 |
| Johnson AC et al. | Parenteral iron formulations differentially affect MCP-1, HO-1, and NGAL gene expression and renal responses to injury. | 2010 | Am. J. Physiol. Renal Physiol. | pmid:20504881 |
| Fernández-Gallego J et al. | [Treatment with intravenous iron and ferritin level]. | 2010 | Nefrologia | pmid:20514109 |
| Do PT et al. | The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. | 2010 | Plant Physiol. | pmid:20841452 |
| Yang Z et al. | Symbiosis between microorganisms from kombucha and kefir: Potential significance to the enhancement of kombucha function. | 2010 | Appl. Biochem. Biotechnol. | pmid:18810658 |