| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arthritis, Rheumatoid | D001172 | 3 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Denton TT et al. | Characterization of D-glucaric acid using NMR, X-ray crystal structure, and MM3 molecular modeling analyses. | 2011 | Carbohydr. Res. | pmid:22015400 |
| Bhattacharya S et al. | D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21982801 |
| Aspuru K et al. | Optimal management of iron deficiency anemia due to poor dietary intake. | 2011 | Int J Gen Med | pmid:22114518 |
| Toblli JE et al. | Evaluation of toxicity and oxidative stress induced by intravenous iron isomaltoside 1000 in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:22164963 |
| Menendez C et al. | Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed? | 2011 | Mol Nutr Food Res | pmid:22144045 |
| Di Nocera PP et al. | Genome organization of epidemic Acinetobacter baumannii strains. | 2011 | BMC Microbiol. | pmid:21985032 |
| Lv YK et al. | Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-yttriate(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836844 |
| Cheng D et al. | A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. | 2011 | Curr Radiopharm | pmid:22191610 |
| Lv YK et al. | Poly[dimethyl-ammonium [aquadi-μ(2)-oxalato-samarate(III)] trihydrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21836843 |
| Nasir A et al. | Management of iron deficiency anaemia in gynaecological patients at Jinnah Postgraduate Medical Centre, Karachi. | 2011 | J Pak Med Assoc | pmid:22356035 |
| Wada Y et al. | [Case report; A case of FGF23-related hypophosphatemic osteomalacia caused by long-term administration of saccharated ferric oxide]. | 2011 | Nippon Naika Gakkai Zasshi | pmid:22175146 |
| Kolodziejczyk J et al. | In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. | 2011 | J. Physiol. Biochem. | pmid:21086198 |
| Vu'o'ng Lê B et al. | New rat models of iron sucrose-induced iron overload. | 2011 | Exp. Biol. Med. (Maywood) | pmid:21685238 |
| Kowalczyk MC et al. | Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors. | 2011 | Oncol. Rep. | pmid:21687956 |
| Evstatiev R et al. | FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease. | 2011 | Gastroenterology | pmid:21699794 |
| Solak Y et al. | Comparison of adverse-event profiles of intravenous low-molecular-weight iron dextran and iron sucrose in peritoneal dialysis patients. | 2011 | Ren Fail | pmid:21401355 |
| Gambini JP et al. | Evaluation of 99mTc-glucarate as a breast cancer imaging agent in a xenograft animal model. | 2011 | Nucl. Med. Biol. | pmid:21315281 |
| Takeda Y et al. | Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients. | 2011 | Am. J. Nephrol. | pmid:21502756 |
| Meier T et al. | Physicochemical and toxicological characterization of a new generic iron sucrose preparation. | 2011 | Arzneimittelforschung | pmid:21428246 |
| Agarwal R et al. | Proteinuria induced by parenteral iron in chronic kidney disease--a comparative randomized controlled trial. | 2011 | Clin J Am Soc Nephrol | pmid:20876669 |
| Auerbach M | Should intravenous iron be upfront therapy for iron deficiency anemia? | 2011 | Pediatr Blood Cancer | pmid:21298731 |
| Crary SE et al. | Intravenous iron sucrose for children with iron deficiency failing to respond to oral iron therapy. | 2011 | Pediatr Blood Cancer | pmid:21298748 |
| Ibert M et al. | Evidence of benzilic rearrangement during the electrochemical oxidation of D-glucose to D-glucaric acid. | 2011 | Carbohydr. Res. | pmid:21269605 |
| Vanderford NL | The role of MafA in regulating cytokine expression in pancreatic beta cells. | 2011 | J. Biol. Chem. | pmid:21239506 |
| Fenwick S and Peebles G | Total dose infusion of intravenous iron in patients with chronic kidney disease receiving haemodialysis. | 2011 | J Ren Care | pmid:21288317 |
| Pai AB et al. | Non-transferrin bound iron, cytokine activation and intracellular reactive oxygen species generation in hemodialysis patients receiving intravenous iron dextran or iron sucrose. | 2011 | Biometals | pmid:21229380 |
| Krafft A and Breymann C | Iron sucrose with and without recombinant erythropoietin for the treatment of severe postpartum anemia: a prospective, randomized, open-label study. | 2011 | J. Obstet. Gynaecol. Res. | pmid:21159035 |
| Stefánsson BV et al. | Acute oxidative stress following intravenous iron injection in patients on chronic hemodialysis: a comparison of iron-sucrose and iron-dextran. | 2011 | Nephron Clin Pract | pmid:21196770 |
| Atalay H et al. | Safety profiles of total dose infusion of low-molecular-weight iron dextran and high-dose iron sucrose in renal patients. | 2011 | Hemodial Int | pmid:21564503 |
| Serrano-Trenas JA et al. | Role of perioperative intravenous iron therapy in elderly hip fracture patients: a single-center randomized controlled trial. | 2011 | Transfusion | pmid:20630042 |
| Malovrh M et al. | The influence of need-based, continuous, low-dose iron replacement on hemoglobin levels in hemodialysis patients treated with erythropoiesis-stimulating agents. | 2011 | Artif Organs | pmid:20618233 |
| Bailie GR et al. | Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America. | 2011 | Arzneimittelforschung | pmid:21755809 |
| Gomollón F and Gisbert JP | IBD: Intravenous iron in IBD--what's the best preparation? | 2011 | Nat Rev Gastroenterol Hepatol | pmid:21788975 |
| Bisbe E et al. | A multicentre comparative study on the efficacy of intravenous ferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery. | 2011 | Br J Anaesth | pmid:21841061 |
| Toblli JE et al. | Assessment of the extent of oxidative stress induced by intravenous ferumoxytol, ferric carboxymaltose, iron sucrose and iron dextran in a nonclinical model. | 2011 | Arzneimittelforschung | pmid:21899208 |
| Goggin MM et al. | Analysis of total and transferrin-bound iron in human serum for pharmacokinetic studies of iron-sucrose formulations. | 2011 | Bioanalysis | pmid:21877893 |
| Yetman AT and Everitt MD | The role of iron deficiency in protein-losing enteropathy following the Fontan procedure. | 2011 Jul-Aug | Congenit Heart Dis | pmid:21392262 |
| Adhikary L and Acharya S | Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. | 2011 Jul-Sep | JNMA J Nepal Med Assoc | pmid:22922860 |
| Moorani KN and Asim S | Parenteral iron sucrose in iron deficiency anaemia of paediatric chronic kidney disease. | 2011 Jul-Sep | J Ayub Med Coll Abbottabad | pmid:23272434 |
| Kowalczyk M et al. | Ferumoxytol: a new era of iron deficiency anemia treatment for patients with chronic kidney disease. | 2011 Nov-Dec | J. Nephrol. | pmid:21956770 |
| Bhattacharya S et al. | Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. | 2011 Nov-Dec | J. Biochem. Mol. Toxicol. | pmid:21538728 |
| Toblli JE et al. | Comparison of oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model. | 2012 | Inflamm Allergy Drug Targets | pmid:22309085 |
| Stachowska-Pietka J et al. | Computer simulations of osmotic ultrafiltration and small-solute transport in peritoneal dialysis: a spatially distributed approach. | 2012 | Am. J. Physiol. Renal Physiol. | pmid:22301624 |
| Muñoz M et al. | Effects of postoperative intravenous iron on transfusion requirements after lower limb arthroplasty. | 2012 | Br J Anaesth | pmid:22337966 |
| Freburger JK et al. | Changing patterns of anemia management in US hemodialysis patients. | 2012 | Am. J. Med. | pmid:22938926 |
| Christoph P et al. | Intravenous iron treatment in pregnancy: comparison of high-dose ferric carboxymaltose vs. iron sucrose. | 2012 | J Perinat Med | pmid:22945271 |
| Rostoker G et al. | Hemodialysis-associated hemosiderosis in the era of erythropoiesis-stimulating agents: a MRI study. | 2012 | Am. J. Med. | pmid:22998881 |
| Okam MM et al. | Comparative rates of adverse events with different formulations of intravenous iron. | 2012 | Am. J. Hematol. | pmid:22965928 |
| Bespalov VG and Aleksandrov VA | [Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors]. | 2012 | Vopr Onkol | pmid:23607211 |
| Lê BV et al. | Modulation of Pseudomonas aeruginosa lipopolysaccharide-induced lung inflammation by chronic iron overload in rat. | 2012 | FEMS Immunol. Med. Microbiol. | pmid:22066700 |