Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Reinisch W et al. | State of the iron: how to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease. | 2013 | J Crohns Colitis | pmid:22917870 |
Kochhar PK et al. | Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial. | 2013 | J. Obstet. Gynaecol. Res. | pmid:22925176 |
Yamamoto S et al. | Iatrogenic osteomalacia: report of two cases. | 2013 | J. UOEH | pmid:23475021 |
GarcÃa Erce JA et al. | [Thoughts about the usefulness of the preoperatory administration of intravenous iron in hip fracture surgery]. | 2013 | Med Clin (Barc) | pmid:23790583 |
Kowalczyk MC et al. | Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice. | 2013 | Int. J. Oncol. | pmid:23835587 |
Beguin Y et al. | Darbepoetin-alfa and intravenous iron administration after autologous hematopoietic stem cell transplantation: a prospective multicenter randomized trial. | 2013 | Am. J. Hematol. | pmid:23873823 |
Munoz C et al. | Klotho sensitivity of the hERG channel. | 2013 | FEBS Lett. | pmid:23603386 |
Lynn S and McDaniel J | Managing severe anemia when the patient is a Jehovah's Witness. | 2013 | JAAPA | pmid:23610833 |
Biggar P and Hahn KM | [Importance of the different i.v. iron generations for everyday medical practice]. | 2013 | MMW Fortschr Med | pmid:23678667 |
Beck-da-Silva L et al. | IRON-HF study: a randomized trial to assess the effects of iron in heart failure patients with anemia. | 2013 | Int. J. Cardiol. | pmid:23680589 |
Goldstein SL et al. | Comparison of the safety and efficacy of 3 iron sucrose iron maintenance regimens in children, adolescents, and young adults with CKD: a randomized controlled trial. | 2013 | Am. J. Kidney Dis. | pmid:23245582 |
Blanco Rubio N et al. | [Preoperative intravenous iron as a strategy for blood saving in surgery for hip fracture]. | 2013 | Med Clin (Barc) | pmid:23246172 |
Lee ES et al. | Comparison of adverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. | 2013 | Curr Med Res Opin | pmid:23252876 |
Bhattacharya S et al. | D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23261973 |
Moore KL et al. | Uncommon adverse effect of a common medication. | 2013 | Tidsskr. Nor. Laegeforen. | pmid:23344600 |
Froessler B et al. | Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial. | 2013 | J. Matern. Fetal. Neonatal. Med. | pmid:23130909 |
Bhattacharya S et al. | The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats. | 2013 | Food Funct | pmid:23138840 |
Devasenapathy N et al. | Is intravenous iron sucrose the treatment of choice for pregnant anemic women? | 2013 | J. Obstet. Gynaecol. Res. | pmid:23167561 |
Wilson PD et al. | An analysis of the health service efficiency and patient experience with two different intravenous iron preparations in a UK anaemia clinic. | 2013 | J Med Econ | pmid:22989163 |
Douard V et al. | Excessive fructose intake causes 1,25-(OH)(2)D(3)-dependent inhibition of intestinal and renal calcium transport in growing rats. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23571713 |
Yang Z et al. | Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity. | 2013 | Infect. Immun. | pmid:23509143 |
Potthoff SA and Münch HG | [Safety aspects of parenteral iron supplementation therapies in patients with chronic kidney disease]. | 2013 | Dtsch. Med. Wochenschr. | pmid:23737117 |
Janus N et al. | Administration of intravenous iron complexes on implantable central venous access port in cancer patients in France: the FERPAC survey. | 2013 | Support Care Cancer | pmid:23715817 |
Beck-da-Silva L et al. | Iron therapy in patients with heart failure. A straight shot. | 2013 | Int. J. Cardiol. | pmid:23931974 |
Vadasz D et al. | Intravenous iron sucrose for restless legs syndrome in pregnant women with low serum ferritin. | 2013 | Sleep Med. | pmid:24012019 |
Tian B et al. | Predicting enzyme-substrate specificity with QM/MM methods: a case study of the stereospecificity of (D)-glucarate dehydratase. | 2013 | Biochemistry | pmid:23901785 |
Abdel-Razeq H et al. | Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study. | 2013 | Drug Des Devel Ther | pmid:24039403 |
Kalaivani K | Use of intravenous iron sucrose for treatment of anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056552 |
Kriplani A et al. | Intravenous iron sucrose therapy for moderate to severe anaemia in pregnancy. | 2013 | Indian J. Med. Res. | pmid:24056559 |
Michigami T | [Updates on rickets and osteomalacia: FGF23-mediated hypophosphatemic rickets/osteomalacia]. | 2013 | Clin Calcium | pmid:24076640 |
Italia K et al. | Hydroxyurea could be a good clinically relevant iron chelator. | 2013 | PLoS ONE | pmid:24349400 |
Grim K et al. | Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. | 2013 | Sleep Med. | pmid:23993871 |
Athibovonsuk P et al. | Prevention of blood transfusion with intravenous iron in gynecologic cancer patients receiving platinum-based chemotherapy. | 2013 | Gynecol. Oncol. | pmid:24099839 |
Ferumoxytol: an intravenous iron, riskier than iron sucrose. | 2013 | Prescrire Int | pmid:24171212 | |
Rowlands M et al. | The effect of intravenous iron on postoperative transfusion requirements in hip fracture patients: study protocol for a randomized controlled trial. | 2013 | Trials | pmid:24015990 |
Kumbasar A et al. | The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. | 2012 Sep-Oct | J. Nephrol. | pmid:22307439 |
Monsénégo J et al. | Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. | 2012 | J. Hepatol. | pmid:22037024 |
Ozkurt S et al. | Acute and subacute effects of EV iron sucrose on endothelial functions in hemodialysis patients. | 2012 | Ren Fail | pmid:22017464 |
Toblli JE et al. | Comparison of oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model. | 2012 | Inflamm Allergy Drug Targets | pmid:22309085 |
Stachowska-Pietka J et al. | Computer simulations of osmotic ultrafiltration and small-solute transport in peritoneal dialysis: a spatially distributed approach. | 2012 | Am. J. Physiol. Renal Physiol. | pmid:22301624 |
Muñoz M et al. | Effects of postoperative intravenous iron on transfusion requirements after lower limb arthroplasty. | 2012 | Br J Anaesth | pmid:22337966 |
Freburger JK et al. | Changing patterns of anemia management in US hemodialysis patients. | 2012 | Am. J. Med. | pmid:22938926 |
Christoph P et al. | Intravenous iron treatment in pregnancy: comparison of high-dose ferric carboxymaltose vs. iron sucrose. | 2012 | J Perinat Med | pmid:22945271 |
Rostoker G et al. | Hemodialysis-associated hemosiderosis in the era of erythropoiesis-stimulating agents: a MRI study. | 2012 | Am. J. Med. | pmid:22998881 |
Okam MM et al. | Comparative rates of adverse events with different formulations of intravenous iron. | 2012 | Am. J. Hematol. | pmid:22965928 |
Bidossi A et al. | A functional genomics approach to establish the complement of carbohydrate transporters in Streptococcus pneumoniae. | 2012 | PLoS ONE | pmid:22428019 |
Galutira PJ and Del Rio M | Understanding renal posttransplantation anemia in the pediatric population. | 2012 | Pediatr. Nephrol. | pmid:22086345 |
Walters KR et al. | Methamphetamine causes anorexia in Drosophila melanogaster, exhausting metabolic reserves and contributing to mortality. | 2012 | J Toxicol Sci | pmid:22863857 |
Bespalov VG and Aleksandrov VA | [Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors]. | 2012 | Vopr Onkol | pmid:23607211 |
Lê BV et al. | Modulation of Pseudomonas aeruginosa lipopolysaccharide-induced lung inflammation by chronic iron overload in rat. | 2012 | FEMS Immunol. Med. Microbiol. | pmid:22066700 |