Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid:11483144 | ||||
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pmid:11513584 | ||||
Murchison LE et al. | Effects of anticonvulsants and inactivity on bone disease in epileptics. | 1975 | Postgrad Med J | pmid:1161672 |
Talafant E et al. | Serum gamma-glutamyl transpeptidase activity and urinary D-glucaric acid excretion in newborns in the first week of life. Effects of phenobarbital and nicethamide combination. | 1976 | Acta Paediatr Scand | pmid:11634 |
Merbouh N et al. | Facile nitroxide-mediated oxidations of D-glucose to D-glucaric acid. | 2001 | Carbohydr. Res. | pmid:11675028 |
Chandler G et al. | Intravenous iron sucrose: establishing a safe dose. | 2001 | Am. J. Kidney Dis. | pmid:11684551 |
Kaltwasser JP et al. | Effect of recombinant human erythropoietin and intravenous iron on anemia and disease activity in rheumatoid arthritis. | 2001 | J. Rheumatol. | pmid:11708414 |
Duffy CI | Iron sucrose or ferric gluconate? | 2001 | Am. J. Kidney Dis. | pmid:11728988 |
Hörl WH | Re: Experience with a large dose (500 mg) of intravenous iron dextran and iron saccharate in peritoneal dialysis patients. | 2001 Sep-Oct | Perit Dial Int | pmid:11757843 |
pmid:11794536 | ||||
Cassimos C et al. | Urinary D-glucaric acid excretion in children with dystonic reactions caused by antiemetic drugs. | 1975 | J. Pediatr. | pmid:1185409 |
Bayoumeu F et al. | [Antipublic antibodies and pregnancy: use of iron sucrose in autologous blood donation with cryopreservation]. | 2002 | Ann Fr Anesth Reanim | pmid:11878118 |
Rooyakkers TM et al. | Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo. | 2002 | Eur. J. Clin. Invest. | pmid:11886426 |
Kooistra MP et al. | Nontransferrin-bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion. | 2002 | Eur. J. Clin. Invest. | pmid:11886430 |
pmid:11887828 | ||||
Hornez JP et al. | [Demonstration of different metabolic pathways starting with glucose or fructose in Rhizobium meliloti]. | 1976 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:11894 |
Arteaga de Murphy C et al. | 99mTc-glucarate for detection of isoproterenol-induced myocardial infarction in rats. | 2002 | Int J Pharm | pmid:11897407 |
pmid:11903138 | ||||
Bayoumeu F et al. | Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route. | 2002 | Am. J. Obstet. Gynecol. | pmid:11904617 |
Marselos M et al. | Evidence that D-glucaro-1,4-lactone shortens the pharmacological action of drugs being disposed via the bile as glucuronides. | 1975 | Biochem. Pharmacol. | pmid:1191334 |
Dittrich E et al. | Efficacy of a low-dose intravenous iron sucrose regimen in peritoneal dialysis patients. | 2002 Jan-Feb | Perit Dial Int | pmid:11929146 |
Sandstad O et al. | D-glucaric acid in common duct bile and relation to choledocholithiasis. | 2002 | Scand. J. Gastroenterol. | pmid:11989842 |
Ibert M et al. | Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid. | 2002 | Carbohydr. Res. | pmid:12039549 |
Hosoya S et al. | Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ. | 2002 | FEMS Microbiol. Lett. | pmid:12044674 |
Harmankaya O and Eran A | Low-dose intravenous iron administration in chronic hemodialysis patients treated with recombinant human erythropoietin. | 2002 | Ren Fail | pmid:12071600 |
Zager RA et al. | Parenteral iron formulations: a comparative toxicologic analysis and mechanisms of cell injury. | 2002 | Am. J. Kidney Dis. | pmid:12087566 |
pmid:12109887 | ||||
Perewusnyk G et al. | Parenteral iron therapy in obstetrics: 8 years experience with iron-sucrose complex. | 2002 | Br. J. Nutr. | pmid:12117422 |
Hermida J et al. | Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment. | 2002 | Clin. Lab. | pmid:12146576 |
Calcium-D-glucarate. | 2002 | Altern Med Rev | pmid:12197785 | |
Silverberg DS et al. | The correction of anemia in severe resistant heart failure with erythropoietin and intravenous iron prevents the progression of both the heart and the renal failure and markedly reduces hospitalization. | 2002 | Clin. Nephrol. | pmid:12227725 |
Lecamwasam DS | Hepatic enzyme induction and its relationship to urinary D-glucaric acid excretion in man. | 1975 | Br J Clin Pharmacol | pmid:1234021 |
Lecamwasam DS et al. | Effect of phenobarbitone on hepatic drug-metabolizing enzymes and urinary D-glucaric acid excretion in man. | 1975 | Br J Clin Pharmacol | pmid:1234506 |
Michaud L et al. | Tolerance and efficacy of intravenous iron saccharate for iron deficiency anemia in children and adolescents receiving long-term parenteral nutrition. | 2002 | Clin Nutr | pmid:12381338 |
Kaizu T | [Non-dialyzable beta-glucuronidase inhibitor in guinea-pig urine. I. Purification (author's transl)]. | 1975 | Yakugaku Zasshi | pmid:1238533 |
Tutor-Crespo MJ et al. | [A study of some indirect biochemical markers in the evaluation of enzymatic induction caused by antiepileptic drugs]. | 2002 Oct 16-31 | Rev Neurol | pmid:12402220 |
pmid:12407646 | ||||
Oldham FB | Continuity of research outcomes: the correlation of bench toxicity mechanisms to clinical outcomes--are they dependable? | 2002 | Am. J. Kidney Dis. | pmid:12407662 |
Boase S and Miners JO | In vitro-in vivo correlations for drugs eliminated by glucuronidation: investigations with the model substrate zidovudine. | 2002 | Br J Clin Pharmacol | pmid:12445028 |
pmid:12455582 | ||||
Yee J and Besarab A | Iron sucrose: the oldest iron therapy becomes new. | 2002 | Am. J. Kidney Dis. | pmid:12460028 |
Oka H et al. | Increased urinary excretion of L-xylulose in patients with liver cirrhosis. | 1976 | Clin. Chim. Acta | pmid:1248150 |
Bauer S et al. | Differential effects of Saint John's Wort (hypericum perforatum) on the urinary excretion of D-glucaric acid and 6beta-hydroxycortisol in healthy volunteers. | 2002 | Eur. J. Clin. Pharmacol. | pmid:12483450 |
Wali A et al. | Comparative study--efficacy, safety and compliance of intravenous iron sucrose and intramuscular iron sorbitol in iron deficiency anemia of pregnancy. | 2002 | J Pak Med Assoc | pmid:12532571 |
Chuang CL et al. | Early prediction of response to intravenous iron supplementation by reticulocyte haemoglobin content and high-fluorescence reticulocyte count in haemodialysis patients. | 2003 | Nephrol. Dial. Transplant. | pmid:12543894 |
Breymann C | Iron deficiency and anaemia in pregnancy: modern aspects of diagnosis and therapy. | 2002 Nov-Dec | Blood Cells Mol. Dis. | pmid:12547241 |
Escartin Marin P et al. | [Enzyme induction in alcoholic and cryptogenetic cirrhoses]. | 1976 | Rev Esp Enferm Apar Dig | pmid:1257561 |
Folkert VW et al. | Chronic use of sodium ferric gluconate complex in hemodialysis patients: safety of higher-dose (> or =250 mg) administration. | 2003 | Am. J. Kidney Dis. | pmid:12612989 |
Beshara S et al. | Pharmacokinetics and red cell utilization of 52Fe/59Fe-labelled iron polymaltose in anaemic patients using positron emission tomography. | 2003 | Br. J. Haematol. | pmid:12614222 |