Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Konjiki O et al. | [A case of hypophosphatemia induced by intravenous administration of saccharated iron oxide]. | 1994 | Nihon Ronen Igakkai Zasshi | pmid:7853746 |
Wada Y et al. | [Case report; A case of FGF23-related hypophosphatemic osteomalacia caused by long-term administration of saccharated ferric oxide]. | 2011 | Nippon Naika Gakkai Zasshi | pmid:22175146 |
Okada M et al. | [2 cases of nonspecific multiple ulcers of the small intestine associated with osteomalacia caused by long-term intravenous administration of saccharated ferric oxide]. | 1982 | Nippon Naika Gakkai Zasshi | pmid:7166673 |
Okuyama T et al. | [Measurement and its fluctuation of urinary glucaric acid in newborns]. | 1993 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:8340644 |
Mizumoto Y et al. | [Measurement and fluctuation of urinary glucaric acid in pregnant women]. | 1994 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:8089594 |
Hartikka P et al. | Effect of iron-saccharin injections of Finnish horses. | 1983 May-Jun | Nord Vet Med | pmid:6889132 |
Micheletti C et al. | [Enzyme induction during treatment with isoniazid]. | 1978 Aug 26-Sep 2 | Nouv Presse Med | pmid:693296 |
Ballinger JR et al. | Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models. | 2003 | Nucl Med Commun | pmid:12717079 |
Liu Z et al. | 99mTc glucarate high-resolution imaging of drug sensitive and drug resistant human breast cancer xenografts in SCID mice. | 2004 | Nucl Med Commun | pmid:15208499 |
Liu Z et al. | Evaluating the protective role of ischaemic preconditioning in rat hearts using a stationary small-animal SPECT imager and 99mTc-glucarate. | 2008 | Nucl Med Commun | pmid:18094633 |
Petrov AD et al. | Targeting human breast tumour in xeno-grafted SCID mice with 99Tcm-glucarate. | 1997 | Nucl Med Commun | pmid:9106778 |
Gambini JP et al. | Evaluation of 99mTc-glucarate as a breast cancer imaging agent in a xenograft animal model. | 2011 | Nucl. Med. Biol. | pmid:21315281 |
Isnardi V et al. | Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? | 2012 | Nucl. Med. Biol. | pmid:23084044 |
Saluk-Juszczak J et al. | Protective effects of D-glucaro-1,4-lactone against oxidative modifications in blood platelets. | 2008 | Nutr Metab Cardiovasc Dis | pmid:17933501 |
Gonçalves P et al. | The effect of high glucose on SERT, the human plasmalemmal serotonin transporter. | 2008 | Nutr Neurosci | pmid:19000377 |
Kim Y et al. | Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. | 2011 | Nutr Res | pmid:22118754 |
Olas B et al. | Protective effects of D-glucaro 1,4-lactone against oxidative/nitrative modifications of plasma proteins. | 2007 | Nutrition | pmid:17234507 |
Franco G and Fonte R | Advances in evaluating liver response to operating theatre work: urinary D-glucaric acid as an index of effect. | 1994 | Occup Med (Lond) | pmid:8167312 |
Kowalczyk MC et al. | Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors. | 2011 | Oncol. Rep. | pmid:21687956 |
Aime S et al. | para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents. | 2005 | Org. Biomol. Chem. | pmid:16240012 |
Berlin I et al. | [The effect of contraceptives on serum lipids, gamma glutamyl transpeptidase and D-glucaric acid elimination]. | 1980 | Orv Hetil | pmid:6110202 |
Gachályi B et al. | [Effect of alpha methyldopa on the mixed oxygenase system of the liver in man]. | 1979 | Orv Hetil | pmid:372883 |
Roth B et al. | [Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)]. | 1977 | Padiatr Padol | pmid:904946 |
Micheletti C et al. | [Enzymatic induction during isoniazid therapy (author's transl)]. | 1979 | Pathol. Biol. | pmid:392418 |
Auerbach M | Should intravenous iron be upfront therapy for iron deficiency anemia? | 2011 | Pediatr Blood Cancer | pmid:21298731 |
Crary SE et al. | Intravenous iron sucrose for children with iron deficiency failing to respond to oral iron therapy. | 2011 | Pediatr Blood Cancer | pmid:21298748 |
Galutira PJ and Del Rio M | Understanding renal posttransplantation anemia in the pediatric population. | 2012 | Pediatr. Nephrol. | pmid:22086345 |
Hörl WH | Iron therapy for renal anemia: how much needed, how much harmful? | 2007 | Pediatr. Nephrol. | pmid:17206511 |
Schröder CH | The management of anemia in pediatric peritoneal dialysis patients. Guidelines by an ad hoc European committee. | 2003 | Pediatr. Nephrol. | pmid:12750985 |
Talafant E et al. | Glucaric acid excretion as index of hepatic glucuronidation in neonates after phenobarbital treatment. | 1975 | Pediatr. Res. | pmid:1134846 |
Talafant E et al. | Negative feedback control of neonatal serum creatine and increased urinary creatinine excretion after enzyme-inducing drugs. | 1977 | Pediatr. Res. | pmid:887306 |
Gourley GR et al. | The effect of saccharolactone on rat intestinal absorption of bilirubin in the presence of human breast milk. | 1989 | Pediatr. Res. | pmid:2704588 |
Levy G et al. | Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion. | 1975 | Pediatrics | pmid:1134883 |
Pollak A et al. | Effect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants. | 2001 | Pediatrics | pmid:11134438 |
Hörl WH | Re: Experience with a large dose (500 mg) of intravenous iron dextran and iron saccharate in peritoneal dialysis patients. | 2001 Sep-Oct | Perit Dial Int | pmid:11757843 |
Dittrich E et al. | Efficacy of a low-dose intravenous iron sucrose regimen in peritoneal dialysis patients. | 2002 Jan-Feb | Perit Dial Int | pmid:11929146 |
Li H and Wang SX | Intravenous iron sucrose in peritoneal dialysis patients with renal anemia. | 2008 Mar-Apr | Perit Dial Int | pmid:18332450 |
Prakash S et al. | Experience with a large dose (500 mg) of intravenous iron dextran and iron saccharate in peritoneal dialysis patients. | 2001 May-Jun | Perit Dial Int | pmid:11475345 |
PERSOONIAL Reflections. | 2009 | Persoonia | pmid:20198167 | |
Barot BS et al. | Physicochemical and structural characterization of iron-sucrose formulations: a comparative study. | 2014 | Pharm Dev Technol | pmid:23701359 |
Sane R et al. | Safe administration of iron sucrose in a patient with a previous hypersensitivity reaction to ferric gluconate. | 2007 | Pharmacotherapy | pmid:17381390 |
Pai AB et al. | Comparison of oxidative stress markers after intravenous administration of iron dextran, sodium ferric gluconate, and iron sucrose in patients undergoing hemodialysis. | 2007 | Pharmacotherapy | pmid:17316146 |
Arató M and Varadi A | On the possible role of enzyme induction in cases of resistancy to chlorpromazine treatment. | 1977 | Pharmakopsychiatr Neuropsychopharmakol | pmid:616930 |
Araki T et al. | Clinical efficacy of two forms of intravenous iron--saccharated ferric oxide and cideferron--for iron deficiency anemia. | 2012 | Pharmazie | pmid:23346769 |
Centeno DC et al. | Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. | 2011 | Plant Cell | pmid:21239646 |
Fior S and Gerola PD | Impact of ubiquitous inhibitors on the GUS gene reporter system: evidence from the model plants Arabidopsis, tobacco and rice and correction methods for quantitative assays of transgenic and endogenous GUS. | 2009 | Plant Methods | pmid:20042078 |
Strack D et al. | Enzymic synthesis of caffeoylglucaric Acid from chlorogenic Acid and glucaric Acid by a protein preparation from tomato cotyledons. | 1987 | Plant Physiol. | pmid:16665274 |
Do PT et al. | The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. | 2010 | Plant Physiol. | pmid:20841452 |
Sudan C et al. | Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants. | 2006 | Planta | pmid:16652220 |
Saluk-Juszczak J | A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. | 2010 | Platelets | pmid:20873960 |