Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kochhar PK et al. | Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial. | 2013 | J. Obstet. Gynaecol. Res. | pmid:22925176 |
Bhattacharya S et al. | D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23261973 |
Moore KL et al. | Uncommon adverse effect of a common medication. | 2013 | Tidsskr. Nor. Laegeforen. | pmid:23344600 |
Froessler B et al. | Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial. | 2013 | J. Matern. Fetal. Neonatal. Med. | pmid:23130909 |
Bhattacharya S et al. | The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats. | 2013 | Food Funct | pmid:23138840 |
Devasenapathy N et al. | Is intravenous iron sucrose the treatment of choice for pregnant anemic women? | 2013 | J. Obstet. Gynaecol. Res. | pmid:23167561 |
Wilson PD et al. | An analysis of the health service efficiency and patient experience with two different intravenous iron preparations in a UK anaemia clinic. | 2013 | J Med Econ | pmid:22989163 |
Douard V et al. | Excessive fructose intake causes 1,25-(OH)(2)D(3)-dependent inhibition of intestinal and renal calcium transport in growing rats. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23571713 |
Yang Z et al. | Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity. | 2013 | Infect. Immun. | pmid:23509143 |
Potthoff SA and Münch HG | [Safety aspects of parenteral iron supplementation therapies in patients with chronic kidney disease]. | 2013 | Dtsch. Med. Wochenschr. | pmid:23737117 |
Janus N et al. | Administration of intravenous iron complexes on implantable central venous access port in cancer patients in France: the FERPAC survey. | 2013 | Support Care Cancer | pmid:23715817 |
Ferumoxytol: an intravenous iron, riskier than iron sucrose. | 2013 | Prescrire Int | pmid:24171212 | |
Rowlands M et al. | The effect of intravenous iron on postoperative transfusion requirements in hip fracture patients: study protocol for a randomized controlled trial. | 2013 | Trials | pmid:24015990 |
Palmer K et al. | Review of available intravenous iron preparations in hemodialysis. | 2013 Apr-Jun | CANNT J | pmid:24069699 |
Mishra A et al. | Fatal anaphylactic reaction to iron sucrose in pregnancy. | 2013 Jan-Feb | Indian J Pharmacol | pmid:23543624 |
Elford P et al. | Biodistribution and predictive hepatic gene expression of intravenous iron sucrose. | 2013 Nov-Dec | J Pharmacol Toxicol Methods | pmid:23624021 |
Soufras GD et al. | Fatal anaphylactic reaction to iron sucrose in pregnancy: iron-induced Kounis syndrome? | 2013 Nov-Dec | Indian J Pharmacol | pmid:24347784 |
Barot BS et al. | Physicochemical and structural characterization of iron-sucrose formulations: a comparative study. | 2014 | Pharm Dev Technol | pmid:23701359 |
Wang Y et al. | Hepatoprotective effects of kombucha tea: identification of functional strains and quantification of functional components. | 2014 | J. Sci. Food Agric. | pmid:23716136 |
Almilaji A et al. | Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein. | 2014 | Kidney Blood Press. Res. | pmid:25571875 |
Sasaki Y et al. | Hepcidin production in response to iron is controlled by monocyte-derived humoral factors. | 2014 | Int. J. Hematol. | pmid:24293278 |
Raman S et al. | Evolution-guided optimization of biosynthetic pathways. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25453111 |
Lu QY et al. | Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase. | 2014 | J Pharm Biomed Anal | pmid:24176739 |
Beguin Y and Jaspers A | Iron sucrose - characteristics, efficacy and regulatory aspects of an established treatment of iron deficiency and iron-deficiency anemia in a broad range of therapeutic areas. | 2014 | Expert Opin Pharmacother | pmid:25186219 |
Price E et al. | A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200 ng/mL. | 2014 | Blood Cells Mol. Dis. | pmid:25065855 |
Kuo KL et al. | Iron sucrose accelerates early atherogenesis by increasing superoxide production and upregulating adhesion molecules in CKD. | 2014 | J. Am. Soc. Nephrol. | pmid:24722448 |
Macdougall IC et al. | A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD. | 2014 | Clin J Am Soc Nephrol | pmid:24458078 |
Contreras C et al. | Comparative study of the oral absorption of microencapsulated ferric saccharate and ferrous sulfate in humans. | 2014 | Eur J Nutr | pmid:23892521 |
Corwin HL and Napolitano LM | Anemia in the critically ill: do we need to live with it?*. | 2014 | Crit. Care Med. | pmid:25126804 |
Pieracci FM et al. | A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. | 2014 | Crit. Care Med. | pmid:24797376 |
Hetzel D et al. | A Phase III, randomized, open-label trial of ferumoxytol compared with iron sucrose for the treatment of iron deficiency anemia in patients with a history of unsatisfactory oral iron therapy. | 2014 | Am. J. Hematol. | pmid:24639149 |
Perelló MF et al. | Intravenous ferrous sucrose versus placebo in addition to oral iron therapy for the treatment of severe postpartum anaemia: a randomised controlled trial. | 2014 | BJOG | pmid:24423186 |
Toyokuni S | Iron overload as a major targetable pathogenesis of asbestos-induced mesothelial carcinogenesis. | 2014 | Redox Rep. | pmid:24257681 |
Onken JE et al. | Ferric carboxymaltose in patients with iron-deficiency anemia and impaired renal function: the REPAIR-IDA trial. | 2014 | Nephrol. Dial. Transplant. | pmid:23963731 |
Shah RB et al. | Pharmaceutical characterization and thermodynamic stability assessment of a colloidal iron drug product: iron sucrose. | 2014 | Int J Pharm | pmid:24440404 |
Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
Airy M et al. | Comparative outcomes of predominant facility-level use of ferumoxytol versus other intravenous iron formulations in incident hemodialysis patients. | 2015 | Nephrol. Dial. Transplant. | pmid:26311216 |
Minami D et al. | Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model. | 2015 | Cancer Sci. | pmid:26211743 |
Ren X et al. | Effect of Intravenous Iron Supplementation on Acute Mountain Sickness: A Preliminary Randomized Controlled Study. | 2015 | Med. Sci. Monit. | pmid:26175087 |
Agarwal R et al. | A randomized trial of intravenous and oral iron in chronic kidney disease. | 2015 | Kidney Int. | pmid:26083656 |
Connor JR et al. | Comparative evaluation of nephrotoxicity and management by macrophages of intravenous pharmaceutical iron formulations. | 2015 | PLoS ONE | pmid:25973894 |
Bhandari S et al. | A randomized, open-label trial of iron isomaltoside 1000 (Monofer®) compared with iron sucrose (Venofer®) as maintenance therapy in haemodialysis patients. | 2015 | Nephrol. Dial. Transplant. | pmid:25925701 |
Toblli JE et al. | Cardiovascular outcomes of intravenous iron in perspective of clinical trials and the use of different iron preparations. | 2015 | Int. J. Cardiol. | pmid:25838213 |
Dai P et al. | Triple Recycling Processes Impact Systemic and Local Bioavailability of Orally Administered Flavonoids. | 2015 | AAPS J | pmid:25762448 |
Toblli JE et al. | Changes in Echocardiographic Parameters in Iron Deficiency Patients with Heart Failure and Chronic Kidney Disease Treated with Intravenous Iron. | 2015 | Heart Lung Circ | pmid:25666998 |
Shiue E et al. | Improving product yields on D-glucose in Escherichia coli via knockout of pgi and zwf and feeding of supplemental carbon sources. | 2015 | Biotechnol. Bioeng. | pmid:25258165 |
Tiwari P et al. | Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. | 2015 | Chem. Biol. Interact. | pmid:25478867 |
Tiwari P et al. | Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. | 2016 | Biochimie | pmid:26655363 |
Fell LH et al. | Impact of individual intravenous iron preparations on the differentiation of monocytes towards macrophages and dendritic cells. | 2016 | Nephrol. Dial. Transplant. | pmid:27190361 |
Song D et al. | AMD-like retinopathy associated with intravenous iron. | 2016 | Exp. Eye Res. | pmid:27565570 |