Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Furuno K et al. | Preventive effect of D-glucarate against renal damage induced by kanamycin. | 1976 | J. Antibiot. | pmid:993134 |
Latham AN et al. | Phenobarbitone-induced urinary excretions of D-glucaric acid and 6beta-hydroxycortisol in man. | 1976 | Can. J. Physiol. Pharmacol. | pmid:991005 |
Roberts C et al. | Glutethimide and enzyme induction. | 1976 | Br Med J | pmid:990872 |
Edelson SB and Cantor DS | Autism: xenobiotic influences. | 1998 Nov-Dec | Toxicol Ind Health | pmid:9891912 |
Sato K and Shiraki M | Saccharated ferric oxide-induced osteomalacia in Japan: iron-induced osteopathy due to nephropathy. | 1998 | Endocr. J. | pmid:9881891 |
Hong SK and Rankin GO | Biotransformation of 2-chloroaniline in the Fischer 344 rat: identification of urinary metabolites. | 1998 | Xenobiotica | pmid:9849645 |
Kuramitsu Y et al. | ND-2001 suppresses lung metastasis of human renal cancer cells in athymic mice. | 1998 | Anticancer Drugs | pmid:9823433 |
Nonaka D et al. | Gelatinous bone marrow transformation complicated by self-induced malnutrition. | 1998 | Acta Haematol. | pmid:9792939 |
pmid:9775031 | ||||
Hubbard BK et al. | Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. | 1998 | Biochemistry | pmid:9772162 |
Sorrell MF et al. | Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis. | 1976 | Clin. Pharmacol. Ther. | pmid:954355 |
Kuramitsu Y et al. | A new anti-metastatic drug, ND-2001, inhibits lung metastases in rat hepatoma cells by suppressing haptotaxis of tumor cells toward laminin. | 1998 | Anticancer Drugs | pmid:9491797 |
al-Hawas F et al. | Use of i.v. iron saccharate in haemodialysis patients not responding to oral iron and erythropoietin. | 1997 | Nephrol. Dial. Transplant. | pmid:9430909 |
Sandle LN et al. | Indirect evidence for hepatic induction in patients with cholesterol gallstones. | 1997 | Biochem. Soc. Trans. | pmid:9388642 |
Cazzola M | Recombinant human erythropoietin to assist autologous blood donation by patients with anemia. | 1997 | J. Lab. Clin. Med. | pmid:9358072 |
Sunder-Plassmann G and Hörl WH | Safety aspects of parenteral iron in patients with end-stage renal disease. | 1997 | Drug Saf | pmid:9352960 |
Furuno K et al. | Effect of D-Glucarates on basic antibiotic-induced renal damage in rats. | 1976 | J. Antibiot. | pmid:931801 |
Cynke E | [Parenteral iron replacement]. | 1997 | Praxis (Bern 1994) | pmid:9312810 |
Hildebrandt AG et al. | Evaluation of in vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo. | 1975 | Eur. J. Clin. Pharmacol. | pmid:9297 |
pmid:9278881 | ||||
Khaw BA et al. | Avidity of technetium 99m glucarate for the necrotic myocardium: in vivo and in vitro assessment. | 1997 Jul-Aug | J Nucl Cardiol | pmid:9278874 |
Beanlands RS et al. | Differentiation of myocardial ischemia and necrosis by technetium 99m glucaric acid kinetics. | 1997 Jul-Aug | J Nucl Cardiol | pmid:9278873 |
Sunder-Plassmann G et al. | The dilemma of evaluating iron status in dialysis patients--limitations of available diagnostic procedures. | 1997 | Nephrol. Dial. Transplant. | pmid:9269632 |
Miguel JC et al. | Effects of iron salts in sucrose on dental caries and plaque in rats. | 1997 | Arch. Oral Biol. | pmid:9233847 |
Narula J et al. | Noninvasive detection of atherosclerotic lesions by 99mTc-based immunoscintigraphic targeting of proliferating smooth muscle cells. | 1997 | Chest | pmid:9187194 |
Scassellati-Sforzolini G et al. | In vivo studies on genotoxicity of pure and commercial linuron. | 1997 | Mutat. Res. | pmid:9186570 |
Brunelle FM and Verbeeck RK | Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat. | 1997 | Life Sci. | pmid:9180355 |
Furuno K et al. | Influence of dehydration and D-glucarate on distribution and excretion of kanamycin in rats. | 1977 | Jpn. J. Pharmacol. | pmid:916384 |
Narula J et al. | Very early noninvasive detection of acute experimental nonreperfused myocardial infarction with 99mTc-labeled glucarate. | 1997 | Circulation | pmid:9118528 |
Petrov AD et al. | Targeting human breast tumour in xeno-grafted SCID mice with 99Tcm-glucarate. | 1997 | Nucl Med Commun | pmid:9106778 |
Walaszek Z et al. | Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention. | 1997 | Cancer Detect. Prev. | pmid:9101079 |
Drzewiecki J | Excretion of D-glucaric acid and metabolism of salicylamide in man: the effect of phenobarbital-produced enzymatic induction. | 1977 Jul-Aug | Pol J Pharmacol Pharm | pmid:905203 |
Roth B et al. | [Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)]. | 1977 | Padiatr Padol | pmid:904946 |
Rost KL et al. | Urinary 6 beta-hydroxycortisol and D-glucaric acid excretion rates are not affected by lansoprazole treatment. | 1997 | Int J Clin Pharmacol Ther | pmid:9021436 |
Bisio S and Franco G | Drinking habits and occupational exposure to xenobiotics: a review. | 1995 Jan-Nov | G Ital Med Lav | pmid:8940655 |
Sunder-Plassmann G and Hörl WH | Safety of intravenous injection of iron saccharate in haemodialysis patients. | 1996 | Nephrol. Dial. Transplant. | pmid:8918625 |
pmid:8902444 | ||||
Talafant E et al. | Negative feedback control of neonatal serum creatine and increased urinary creatinine excretion after enzyme-inducing drugs. | 1977 | Pediatr. Res. | pmid:887306 |
Brunelle FM and Verbeeck RK | Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. | 1996 | Xenobiotica | pmid:8867997 |
Lorincz M et al. | Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase. | 1996 | Cytometry | pmid:8866216 |
Silverberg DS et al. | Intravenous ferric saccharate as an iron supplement in dialysis patients. | 1996 | Nephron | pmid:8852489 |
Monarca S et al. | Biological monitoring of workers exposed to N-nitrosodiethanolamine in the metal industry. | 1996 | Environ. Health Perspect. | pmid:8834865 |
Kawasaki H et al. | Effect of corticosteroid treatment on bilirubin metabolism in chronic aggressive hepatitis. | 1977 | Acta Hepatogastroenterol (Stuttg) | pmid:883466 |
Moretti M et al. | Biological monitoring of genotoxic hazard in workers of the rubber industry. | 1996 | Environ. Health Perspect. | pmid:8781380 |
Addyman R et al. | Urinary glucaric acid excretion in rheumatoid arthritis: influence of disease activity and disease modifying drugs. | 1996 | Ann. Rheum. Dis. | pmid:8774168 |
Fujihira E and Whitehouse MW | Pathobiodynamics: reduced ascorbate excretion by rats with severe inflammation. | 1977 | Proc. Soc. Exp. Biol. Med. | pmid:877135 |
Meyer MP et al. | A comparison of oral and intravenous iron supplementation in preterm infants receiving recombinant erythropoietin. | 1996 | J. Pediatr. | pmid:8765624 |
Sung RY et al. | Urinary D-glucaric acid excretion in idiopathic neonatal jaundice. | 1996 | Chin. Med. J. | pmid:8758309 |
Tryba M | Epoetin alfa plus autologous blood donation in patients with a low hematocrit scheduled to undergo orthopedic surgery. | 1996 | Semin. Hematol. | pmid:8723577 |
Mercuriali F | Epoetin alfa for autologous blood donation in patients with rheumatoid arthritis and concomitant anemia. | 1996 | Semin. Hematol. | pmid:8723576 |