Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Steinberg KK and Needham LL | A comparison of two methods for quantifying D-glucaric acid. | 1986 Jul-Aug | J Anal Toxicol | pmid:3747452 |
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RICHTER GW | Intranuclear aggregates of ferritin in liver cells of mice treated with saccharated iron oxide. Their possible relation to nuclear protein synthesis. | 1961 | J Biophys Biochem Cytol | pmid:13741388 |
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Okada DR et al. | Myocardial kinetics of Tc-99m glucarate in low flow, hypoxia, and aglycemia. | 2003 Mar-Apr | J Nucl Cardiol | pmid:12673182 |
Beanlands RS et al. | Differentiation of myocardial ischemia and necrosis by technetium 99m glucaric acid kinetics. | 1997 Jul-Aug | J Nucl Cardiol | pmid:9278873 |
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Johnson LL et al. | Technetium-99m glucarate uptake in a swine model of limited flow plus increased demand. | 2000 Nov-Dec | J Nucl Cardiol | pmid:11144474 |
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Németh I et al. | Hyperbilirubinemia and urinary D-glucaric acid excretion in premature infants following antepartum dexamethasone treatment. | 1981 | J Perinat Med | pmid:6783743 |
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Lu QY et al. | Overestimation of flavonoid aglycones as a result of the ex vivo deconjugation of glucuronides by the tissue β-glucuronidase. | 2014 | J Pharm Biomed Anal | pmid:24176739 |
Tutor-Crespo M et al. | Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs. | 2004 | J Pharm Pharm Sci | pmid:15576017 |
Lai AA and Levy RH | Pharmacokinetic description of drug interactions by enzyme induction: carbamazepine-clonazepam in monkeys. | 1979 | J Pharm Sci | pmid:108383 |
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Collinot JP et al. | Evaluation of urinary D-glucaric acid excretion in workers exposed to butyl glycol. | 1996 | J Toxicol Environ Health | pmid:8691506 |
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Steinberg KK et al. | Assessment of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure using a modified D-glucaric acid assay. | 1985 | J Toxicol Environ Health | pmid:4093993 |
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Liu Y et al. | New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells. | 2004 | J. Am. Chem. Soc. | pmid:15198572 |
Liu Y and Reineke TM | Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery. | 2005 | J. Am. Chem. Soc. | pmid:15740138 |
Toblli JE et al. | Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency. | 2007 | J. Am. Coll. Cardiol. | pmid:17950147 |
Francis GS and Kanderian A | Anemia and heart failure a new pathway? | 2007 | J. Am. Coll. Cardiol. | pmid:17950148 |