Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Raman S et al. | Evolution-guided optimization of biosynthetic pathways. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25453111 |
| Tiwari P et al. | Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. | 2015 | Chem. Biol. Interact. | pmid:25478867 |
| pmid:25514744 | ||||
| pmid:25514745 | ||||
| Almilaji A et al. | Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein. | 2014 | Kidney Blood Press. Res. | pmid:25571875 |
| pmid:25609135 | ||||
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| Toblli JE et al. | Changes in Echocardiographic Parameters in Iron Deficiency Patients with Heart Failure and Chronic Kidney Disease Treated with Intravenous Iron. | 2015 | Heart Lung Circ | pmid:25666998 |
| pmid:25698609 | ||||
| Freche JP et al. | [Variation in the urinary excretion of 6-beta-hydroxycortisol in humans after administration of the new isoquinoline derivative, PK-11195 (52028 RP)]. | 1989 Sep-Oct | Therapie | pmid:2573163 |
| pmid:25754747 | ||||
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| Toblli JE et al. | Cardiovascular outcomes of intravenous iron in perspective of clinical trials and the use of different iron preparations. | 2015 | Int. J. Cardiol. | pmid:25838213 |
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| Bhandari S et al. | A randomized, open-label trial of iron isomaltoside 1000 (Monofer®) compared with iron sucrose (Venofer®) as maintenance therapy in haemodialysis patients. | 2015 | Nephrol. Dial. Transplant. | pmid:25925701 |
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| Connor JR et al. | Comparative evaluation of nephrotoxicity and management by macrophages of intravenous pharmaceutical iron formulations. | 2015 | PLoS ONE | pmid:25973894 |
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| Agarwal R et al. | A randomized trial of intravenous and oral iron in chronic kidney disease. | 2015 | Kidney Int. | pmid:26083656 |
| pmid:26118386 | ||||
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| Minami D et al. | Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model. | 2015 | Cancer Sci. | pmid:26211743 |
| Airy M et al. | Comparative outcomes of predominant facility-level use of ferumoxytol versus other intravenous iron formulations in incident hemodialysis patients. | 2015 | Nephrol. Dial. Transplant. | pmid:26311216 |
| pmid:26385819 | ||||
| pmid:26422625 | ||||
| pmid:26526024 | ||||
| pmid:26575062 | ||||
| pmid:26605680 | ||||
| pmid:26637994 | ||||
| Mori M et al. | Urinary and biliary metabolites of mephentermine in male Wistar rats. | 1989 | Xenobiotica | pmid:2665325 |
| Tiwari P et al. | Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. | 2016 | Biochimie | pmid:26655363 |
| pmid:26657161 | ||||
| Bitsi S et al. | Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes. | 2016 | Am. J. Physiol. Endocrinol. Metab. | pmid:26670484 |
| pmid:26686338 | ||||
| pmid:26749401 | ||||
| pmid:26796581 | ||||
| Lee T et al. | Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD. | 2017 | Gut | pmid:26848182 |
| pmid:26868063 | ||||
| pmid:26901550 | ||||
| pmid:26934422 |