Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
---|
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Okada DR et al. | Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate. | 2004 | J. Nucl. Med. | pmid:15073263 |
Willerson JT | Detection of acute myocardial infarcts by infarct-avid imaging. | 1991 | J. Nucl. Med. | pmid:1846912 |
Liu Z et al. | High-resolution imaging with (99m)Tc-glucarate for assessing myocardial injury in rat heart models exposed to different durations of ischemia with reperfusion. | 2004 | J. Nucl. Med. | pmid:15235074 |
Kochhar PK et al. | Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial. | 2013 | J. Obstet. Gynaecol. Res. | pmid:22925176 |
Devasenapathy N et al. | Is intravenous iron sucrose the treatment of choice for pregnant anemic women? | 2013 | J. Obstet. Gynaecol. Res. | pmid:23167561 |
Krafft A and Breymann C | Iron sucrose with and without recombinant erythropoietin for the treatment of severe postpartum anemia: a prospective, randomized, open-label study. | 2011 | J. Obstet. Gynaecol. Res. | pmid:21159035 |
Gehret TC et al. | Convenient large-scale synthesis of D-glucaro-1,4:6,3-dilactone. | 2009 | J. Org. Chem. | pmid:19777999 |
Cassimos C et al. | Urinary D-glucaric acid excretion in children with dystonic reactions caused by antiemetic drugs. | 1975 | J. Pediatr. | pmid:1185409 |
Cassimos C et al. | Urinary D-glucaric acid excretion in normal and G-6-PD-deficient children with favism. | 1974 | J. Pediatr. | pmid:4826626 |
Meyer MP et al. | A comparison of oral and intravenous iron supplementation in preterm infants receiving recombinant erythropoietin. | 1996 | J. Pediatr. | pmid:8765624 |
Fujimoto T et al. | A new clinical prognostic predictor for patients with biliary atresia. | 1994 | J. Pediatr. Surg. | pmid:8078014 |
Garnham JC et al. | The effect of repeated administration of diftalone on enzyme induction. | 1978 | J. Pharm. Pharmacol. | pmid:27604 |
Oleson L and Court MH | Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases. | 2008 | J. Pharm. Pharmacol. | pmid:18718121 |
Latham AN | D-Glucaric acid as an index of hepatic enzyme induction by anticonvulsant drugs in man. | 1974 | J. Pharm. Pharmacol. | pmid:4151390 |
Latham AN | Effect of in vitro changes in urinary pH on the enzymatic measurement and daily variation in excretion of D-glucaric acid. | 1975 | J. Pharm. Pharmacol. | pmid:239180 |
Tanaka E et al. | Studies on the trimethadione metabolism as a tool for the assessment of drug-metabolizing capacity using plasma and urine of rats pretreated with phenobarbital and 3-methylcholanthrene. | 1982 | J. Pharmacobio-dyn. | pmid:7097483 |
Bologa M et al. | Pregnancy-induced changes in drug metabolism in epileptic women. | 1991 | J. Pharmacol. Exp. Ther. | pmid:2033516 |
Patel IH et al. | Induction effect of phenobarbital on the carbamazepine to carbamazepine-10, 11-epoxide pathway in rhesus monkeys. | 1981 | J. Pharmacol. Exp. Ther. | pmid:7229992 |
Tutor-Crespo MJ et al. | Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects. | 2005 | J. Pharmacol. Sci. | pmid:16314692 |
Kolodziejczyk J et al. | In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. | 2011 | J. Physiol. Biochem. | pmid:21086198 |
Kaltwasser JP et al. | Effect of recombinant human erythropoietin and intravenous iron on anemia and disease activity in rheumatoid arthritis. | 2001 | J. Rheumatol. | pmid:11708414 |
Wang Y et al. | Hepatoprotective effects of kombucha tea: identification of functional strains and quantification of functional components. | 2014 | J. Sci. Food Agric. | pmid:23716136 |
Yamamoto S et al. | Iatrogenic osteomalacia: report of two cases. | 2013 | J. UOEH | pmid:23475021 |
Lynn S and McDaniel J | Managing severe anemia when the patient is a Jehovah's Witness. | 2013 | JAAPA | pmid:23610833 |
Gorder V et al. | Treatment of restless legs syndrome with iron infusion therapy. | 2009 | JAAPA | pmid:19354112 |
Smith TG et al. | Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials. | 2009 | JAMA | pmid:19809026 |
Adhikary L and Acharya S | Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. | 2011 Jul-Sep | JNMA J Nepal Med Assoc | pmid:22922860 |
Tsuruoka T et al. | Inhibition of pulmonary metastases and tumor cell invasion in experimental tumors by sodium D-glucaro-delta-lactam (ND2001). | 1995 | Jpn. J. Cancer Res. | pmid:7737908 |
Tsuruoka T et al. | Inhibition of tumor cell haptotaxis by sodium D-glucaro-delta-lactam (ND2001). | 1995 | Jpn. J. Cancer Res. | pmid:8567400 |
Furuno K et al. | Influence of dehydration and D-glucarate on distribution and excretion of kanamycin in rats. | 1977 | Jpn. J. Pharmacol. | pmid:916384 |
Furuno K et al. | Effect of D-glucaric acid derivatives on stability of rat liver lysosomes and erythrocytes. | 1974 | Jpn. J. Pharmacol. | pmid:4463271 |
Hinohara Y et al. | Glucuronic acid pathway in alloxan diabetic rabbits. (I). Urinary excretion of metabolites related to the glucuronic acid pathway. | 1974 | Jpn. J. Pharmacol. | pmid:4463273 |
Higashi T et al. | [Relative Ga-67 image enhancement by iron-loading]. | 1984 | Kaku Igaku | pmid:6593479 |
Tanaka H et al. | [A growth media of genus Legionella in containing saccharated ferric oxide (Fesin) replacing soluble ferric pyrophosphate (author's transl)]. | 1982 | Kansenshogaku Zasshi | pmid:6809855 |
Almilaji A et al. | Regulation of the voltage gated K channel Kv1.3 by recombinant human klotho protein. | 2014 | Kidney Blood Press. Res. | pmid:25571875 |
Keven K et al. | Combination of intravenous iron sucrose and ascorbic acid in hemodialysis patients. | 2005 | Kidney Int. | pmid:15954940 |
Agarwal R | Is i.v. iron really superior in CKD patients not on dialysis? | 2006 | Kidney Int. | pmid:16957750 |
Zager RA | Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy. | 2005 | Kidney Int. | pmid:16164630 |
Agarwal R | Proinflammatory effects of iron sucrose in chronic kidney disease. | 2006 | Kidney Int. | pmid:16609688 |
Deicher R et al. | High-dose parenteral iron sucrose depresses neutrophil intracellular killing capacity. | 2003 | Kidney Int. | pmid:12846772 |
Agarwal R | Transferrin saturation with intravenous irons: an in vitro study. | 2004 | Kidney Int. | pmid:15327409 |
Aronoff GR et al. | Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens. | 2004 | Kidney Int. | pmid:15327417 |
Zager RA et al. | Parenteral iron nephrotoxicity: potential mechanisms and consequences. | 2004 | Kidney Int. | pmid:15200421 |
Zager RA et al. | Combined iron sucrose and protoporphyrin treatment protects against ischemic and toxin-mediated acute renal failure. | 2016 | Kidney Int. | pmid:27165818 |
Agarwal R et al. | A randomized trial of intravenous and oral iron in chronic kidney disease. | 2015 | Kidney Int. | pmid:26083656 |
Vikrant S | Optimum dosage regimen for iron sucrose. | 2007 | Kidney Int. | pmid:17625585 |
Jaber BL | Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease. | 2008 | Kidney Int. | pmid:18235527 |
Lim R et al. | A permanent tan from iron. | 2008 | Kidney Int. | pmid:18340355 |
Auerbach M and Al Talib K | Low-molecular weight iron dextran and iron sucrose have similar comparative safety profiles in chronic kidney disease. | 2008 | Kidney Int. | pmid:18274543 |
Schaller G et al. | Intravenous iron increases labile serum iron but does not impair forearm blood flow reactivity in dialysis patients. | 2005 | Kidney Int. | pmid:16316358 |