Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Parkinson Disease D010300 53 associated lipids
von Willebrand Diseases D014842 2 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Atherosclerosis D050197 85 associated lipids
Insulin Resistance D007333 99 associated lipids
Dehydration D003681 11 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Critical Illness D016638 13 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Myocardial Stunning D017682 10 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Carcinogenesis D063646 3 associated lipids
Blood Loss, Surgical D016063 6 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
Iron Overload D019190 11 associated lipids
Anemia, Refractory D000753 3 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Anemia, Neonatal D000751 1 associated lipids
Gilbert Disease D005878 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Bailie GR et al. Parenteral iron use in the management of anemia in end-stage renal disease patients. 2000 Am. J. Kidney Dis. pmid:10620537
Descombes E and Fellay G Improved response to erythropoietin therapy with long-term continuous iron supplementation. 2000 Nephron pmid:10657727
Fujii Y et al. Inhibition of liver metastases and tumor cell invasion in spontaneous liver metastasis model (LMFS) by sodium D-glucaro-delta-lactam (ND2001). 2000 Biomed. Pharmacother. pmid:10759292
Monterrubio R et al. A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli. 2000 J. Bacteriol. pmid:10762278
Gulick AM et al. Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli. 2000 Biochemistry pmid:10769114
Wiersema AM et al. Early assessment of skeletal muscle damage after ischaemia-reperfusion injury using Tc-99m-glucarate. 2000 Cardiovasc Surg pmid:10799826
Fujita K et al. Establishment of Salmonella strain expressing catalytically active human UDP-glucuronosyltransferase 1A1 (UGT1A1). 2000 Life Sci. pmid:10821120
Wargovich MJ et al. Efficacy of potential chemopreventive agents on rat colon aberrant crypt formation and progression. 2000 Carcinogenesis pmid:10837003
Lai AA and Levy RH Pharmacokinetic description of drug interactions by enzyme induction: carbamazepine-clonazepam in monkeys. 1979 J Pharm Sci pmid:108383
Van Wyck DB et al. Safety and efficacy of iron sucrose in patients sensitive to iron dextran: North American clinical trial. 2000 Am. J. Kidney Dis. pmid:10873877
Gombotz H et al. Preoperative treatment with recombinant human erythropoietin or predeposit of autologous blood in women undergoing primary hip replacement. 2000 Acta Anaesthesiol Scand pmid:10903019
Krafft A et al. Intravenous iron sucrose in two pregnant women with inflammatory bowel disease and severe iron deficiency anemia. 2000 Acta Obstet Gynecol Scand pmid:10949245
van Iperen CE et al. Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients. 2000 Crit. Care Med. pmid:10966249
Matsuo E et al. Acid mucopolysaccharide metabolism in leprosy. 3. Hyaluronic acid mycobacterial growth enhancement, and growth suppression by saccharic acid and vitamin C as inhibitors of beta-glucuronidase. 1975 Jan-Mar Int. J. Lepr. Other Mycobact. Dis. pmid:1099016
Parkkinen J et al. Catalytically active iron and bacterial growth in serum of haemodialysis patients after i.v. iron-saccharate administration. 2000 Nephrol. Dial. Transplant. pmid:11071973
Kao HH et al. Clinical characteristic of parenteral iron supplementation in hemodialysis patients receiving erythropoietin therapy. 2000 Chang Gung Med J pmid:11126152
Fishbane S and Kowalski EA The comparative safety of intravenous iron dextran, iron saccharate, and sodium ferric gluconate. 2000 Nov-Dec Semin Dial pmid:11130261
Pollak A et al. Effect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants. 2001 Pediatrics pmid:11134438
Johnson LL et al. Technetium-99m glucarate uptake in a swine model of limited flow plus increased demand. 2000 Nov-Dec J Nucl Cardiol pmid:11144474
Charytan C et al. Efficacy and safety of iron sucrose for iron deficiency in patients with dialysis-associated anemia: North American clinical trial. 2001 Am. J. Kidney Dis. pmid:11157370