Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Parkinson Disease D010300 53 associated lipids
von Willebrand Diseases D014842 2 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Atherosclerosis D050197 85 associated lipids
Insulin Resistance D007333 99 associated lipids
Dehydration D003681 11 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Critical Illness D016638 13 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Myocardial Stunning D017682 10 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Carcinogenesis D063646 3 associated lipids
Blood Loss, Surgical D016063 6 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
Iron Overload D019190 11 associated lipids
Anemia, Refractory D000753 3 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Anemia, Neonatal D000751 1 associated lipids
Gilbert Disease D005878 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
ELLIS JT Glomerular lesions and the nephrotic syndrome in rabbits given saccharated iron oxide intravenously; with special reference to the part played by intracapillary precipitates in the pathogenesis of the lesions. 1956 J. Exp. Med. pmid:13278460
Pietrantonio AM et al. [Urinary measurement of D-glucaric acid in operating room personnel in the Modena USL 16 hospitals]. 1992 Jan-Nov G Ital Med Lav pmid:1345728
BOYLAND E et al. Enzyme activity in relation to cancer: inhibition of urinary beta-glucuronidase of patients with cancer of the bladder by oral administration of 1:4-saccharolactone and related compounds. 1957 Br. J. Cancer pmid:13510516
Pistelli A et al. [Contribution of glutathione to detoxification in alcoholism. Biochemical-clinical studies]. 1992 Clin Ter pmid:1358498
RICHTER GW The cellular transformation of injected colloidal iron complexes into ferritin and hemosiderin in experimental animals; a study with the aid of electron microscopy. 1959 J. Exp. Med. pmid:13620849
RICHTER GW Intranuclear aggregates of ferritin in liver cells of mice treated with saccharated iron oxide. Their possible relation to nuclear protein synthesis. 1961 J Biophys Biochem Cytol pmid:13741388
Abou-Issa H et al. Antitumour synergism between non-toxic dietary combinations of isotretinoin and glucarate. 1992 Eur. J. Cancer pmid:1388036
Herzberg M et al. D-Glucaric acid and gamma-glutamyltransferase as indices of hepatic enzyme induction in pregnancy. 1977 Clin. Chem. pmid:13946
pmid:14089452
Ohtani H et al. Comparison of technetium-99m-glucarate and thallium-201 for the identification of acute myocardial infarction in rats. 1992 J. Nucl. Med. pmid:1432160
Séronie-Vivien S et al. Epoetin alfa and intravenous iron sucrose to treat severe anemia in a patient with chronic radiation enteropathy: a case report. 2003 Med. Oncol. pmid:14514981
Blaustein DA et al. The safety and efficacy of an accelerated iron sucrose dosing regimen in patients with chronic kidney disease. 2003 Kidney Int. Suppl. pmid:14531777
Colfer M Achieving optimal patient outcomes with intravenous iron. 2003 Nephrol Nurs J pmid:14533524
Mukhin IV and Nikolenko VIu [Experimental systemic enzyme therapy of gouty and primary glomerulonephritis]. 2003 Jul-Aug Eksp Klin Farmakol pmid:14558349
Verma P et al. Decolorization of synthetic dyes using a copper complex with glucaric acid. 2004 Chemosphere pmid:14575741
Geisser P Reactivity of iron compounds. 2003 Am. J. Kidney Dis. pmid:14582056
Danielson BG and Beshara S Pharmacokinetics and utilization of iron sucrose. 2003 Am. J. Kidney Dis. pmid:14582057
Folkert VW Intravenous iron therapy in chronic kidney disease and peritoneal dialysis patients. 2003 Nephrol Nurs J pmid:14621635
Breborowicz M et al. Effect of iron sucrose on human peritoneal mesothelial cells. 2003 Eur. J. Clin. Invest. pmid:14636286
Tutor-Crespo MJ et al. Assessment of copper status in epileptic patients treated with anticonvulsant drugs by measuring the specific oxidase activity of ceruloplasmin. 2003 Epilepsy Res. pmid:14642999