Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Kidney Failure, Chronic D007676 51 associated lipids
Kidney Diseases D007674 29 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Insulin Resistance D007333 99 associated lipids
Inflammation D007249 119 associated lipids
Hypotension D007022 41 associated lipids
Hypocalcemia D006996 12 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hyperplasia D006965 34 associated lipids
Hyperlipidemias D006949 73 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Biggar P and Hahn KM [Importance of the different i.v. iron generations for everyday medical practice]. 2013 MMW Fortschr Med pmid:23678667
Beck-da-Silva L et al. IRON-HF study: a randomized trial to assess the effects of iron in heart failure patients with anemia. 2013 Int. J. Cardiol. pmid:23680589
Michigami T [Updates on rickets and osteomalacia: FGF23-mediated hypophosphatemic rickets/osteomalacia]. 2013 Clin Calcium pmid:24076640
Italia K et al. Hydroxyurea could be a good clinically relevant iron chelator. 2013 PLoS ONE pmid:24349400
Grim K et al. Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. 2013 Sleep Med. pmid:23993871
Kumbasar A et al. The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. 2012 Sep-Oct J. Nephrol. pmid:22307439
Okam MM et al. Comparative rates of adverse events with different formulations of intravenous iron. 2012 Am. J. Hematol. pmid:22965928
Borchard G et al. Nanoparticle iron medicinal products - Requirements for approval of intended copies of non-biological complex drugs (NBCD) and the importance of clinical comparative studies. 2012 Regul. Toxicol. Pharmacol. pmid:22951348
Yamamoto S et al. Fibroblast growth factor 23-related osteomalacia caused by the prolonged administration of saccharated ferric oxide. 2012 Intern. Med. pmid:22975552
Ernst MC et al. Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. 2012 Endocrinology pmid:22186410
Kamanna VS et al. Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. 2012 Am. J. Nephrol. pmid:22212390
Stein J et al. Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. 2012 Curr Med Res Opin pmid:22181342
Rashid K et al. Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. 2012 Free Radic. Res. pmid:22239106
Ichii H et al. Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. 2012 Am. J. Nephrol. pmid:22722756
Pfenniger A et al. Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. 2012 J Perinat Med pmid:22752771
da Silva Krause M et al. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. 2012 J. Endocrinol. pmid:22761278
Araki T et al. Clinical efficacy of two forms of intravenous iron--saccharated ferric oxide and cideferron--for iron deficiency anemia. 2012 Pharmazie pmid:23346769
Isnardi V et al. Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? 2012 Nucl. Med. Biol. pmid:23084044
Xia B et al. A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. 2012 Mol. Pharm. pmid:23033922
Smith TN et al. Modifications in the nitric acid oxidation of D-glucose. 2012 Carbohydr. Res. pmid:22285512