| MeSH term | MeSH ID | Detail |
|---|---|---|
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Mycobacterium Infections | D009164 | 7 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Osteomalacia | D010018 | 5 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Peritoneal Neoplasms | D010534 | 16 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matsuoka S et al. | Correlation between the level of urinary D-glucaric acid and the degree of activation of masked compound (FT-207) in cancer patients. | 1981 | Tohoku J. Exp. Med. | pmid:6797104 |
| Hanaue H et al. | Estimation of the functional reserve of the human liver by urinary D-glucaric acid excretion after vitamin C administration. | 1993 | Tokai J. Exp. Clin. Med. | pmid:7940601 |
| Edelson SB and Cantor DS | Autism: xenobiotic influences. | 1998 Nov-Dec | Toxicol Ind Health | pmid:9891912 |
| Bhattacharya S et al. | D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21982801 |
| Bhattacharya S et al. | D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23261973 |
| Tiwari P and Gupta KP | Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24792773 |
| Apostoli P et al. | Relationship between PCBs in blood and D-glucaric acid in urine. | 2003 | Toxicol. Lett. | pmid:12919720 |
| Gupta KP and Singh J | Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin. | 2004 | Toxicol. Sci. | pmid:14976333 |
| Meier JR et al. | Urine mutagenicity and biochemical effects of the drinking water mutagen, 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX), following repeated oral administration to mice and rats. | 1996 | Toxicology | pmid:8658560 |
| Oredipe OA et al. | Dietary glucarate-mediated inhibition of initiation of diethylnitrosamine-induced hepatocarcinogenesis. | 1992 | Toxicology | pmid:1519243 |