Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
Hemosiderosis D006486 1 associated lipids
Rickets, Hypophosphatemic D063730 1 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Anemia, Neonatal D000751 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Furuno K et al. Preventive effect of D-glucarate against renal damage induced by kanamycin. 1976 J. Antibiot. pmid:993134
Latham AN et al. Phenobarbitone-induced urinary excretions of D-glucaric acid and 6beta-hydroxycortisol in man. 1976 Can. J. Physiol. Pharmacol. pmid:991005
Roberts C et al. Glutethimide and enzyme induction. 1976 Br Med J pmid:990872
Edelson SB and Cantor DS Autism: xenobiotic influences. 1998 Nov-Dec Toxicol Ind Health pmid:9891912
Sato K and Shiraki M Saccharated ferric oxide-induced osteomalacia in Japan: iron-induced osteopathy due to nephropathy. 1998 Endocr. J. pmid:9881891
Hong SK and Rankin GO Biotransformation of 2-chloroaniline in the Fischer 344 rat: identification of urinary metabolites. 1998 Xenobiotica pmid:9849645
Kuramitsu Y et al. ND-2001 suppresses lung metastasis of human renal cancer cells in athymic mice. 1998 Anticancer Drugs pmid:9823433
Nonaka D et al. Gelatinous bone marrow transformation complicated by self-induced malnutrition. 1998 Acta Haematol. pmid:9792939
pmid:9775031
Hubbard BK et al. Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. 1998 Biochemistry pmid:9772162
Sorrell MF et al. Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis. 1976 Clin. Pharmacol. Ther. pmid:954355
Kuramitsu Y et al. A new anti-metastatic drug, ND-2001, inhibits lung metastases in rat hepatoma cells by suppressing haptotaxis of tumor cells toward laminin. 1998 Anticancer Drugs pmid:9491797
al-Hawas F et al. Use of i.v. iron saccharate in haemodialysis patients not responding to oral iron and erythropoietin. 1997 Nephrol. Dial. Transplant. pmid:9430909
Sandle LN et al. Indirect evidence for hepatic induction in patients with cholesterol gallstones. 1997 Biochem. Soc. Trans. pmid:9388642
Cazzola M Recombinant human erythropoietin to assist autologous blood donation by patients with anemia. 1997 J. Lab. Clin. Med. pmid:9358072
Sunder-Plassmann G and Hörl WH Safety aspects of parenteral iron in patients with end-stage renal disease. 1997 Drug Saf pmid:9352960
Furuno K et al. Effect of D-Glucarates on basic antibiotic-induced renal damage in rats. 1976 J. Antibiot. pmid:931801
Cynke E [Parenteral iron replacement]. 1997 Praxis (Bern 1994) pmid:9312810
Hildebrandt AG et al. Evaluation of in vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo. 1975 Eur. J. Clin. Pharmacol. pmid:9297
pmid:9278881
Khaw BA et al. Avidity of technetium 99m glucarate for the necrotic myocardium: in vivo and in vitro assessment. 1997 Jul-Aug J Nucl Cardiol pmid:9278874
Beanlands RS et al. Differentiation of myocardial ischemia and necrosis by technetium 99m glucaric acid kinetics. 1997 Jul-Aug J Nucl Cardiol pmid:9278873
Sunder-Plassmann G et al. The dilemma of evaluating iron status in dialysis patients--limitations of available diagnostic procedures. 1997 Nephrol. Dial. Transplant. pmid:9269632
Miguel JC et al. Effects of iron salts in sucrose on dental caries and plaque in rats. 1997 Arch. Oral Biol. pmid:9233847
Narula J et al. Noninvasive detection of atherosclerotic lesions by 99mTc-based immunoscintigraphic targeting of proliferating smooth muscle cells. 1997 Chest pmid:9187194
Scassellati-Sforzolini G et al. In vivo studies on genotoxicity of pure and commercial linuron. 1997 Mutat. Res. pmid:9186570
Brunelle FM and Verbeeck RK Conjugation-deconjugation cycling of diflunisal via beta-glucuronidase catalyzed hydrolysis of its acyl glucuronide in the rat. 1997 Life Sci. pmid:9180355
Furuno K et al. Influence of dehydration and D-glucarate on distribution and excretion of kanamycin in rats. 1977 Jpn. J. Pharmacol. pmid:916384
Narula J et al. Very early noninvasive detection of acute experimental nonreperfused myocardial infarction with 99mTc-labeled glucarate. 1997 Circulation pmid:9118528
Petrov AD et al. Targeting human breast tumour in xeno-grafted SCID mice with 99Tcm-glucarate. 1997 Nucl Med Commun pmid:9106778
Walaszek Z et al. Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention. 1997 Cancer Detect. Prev. pmid:9101079
Drzewiecki J Excretion of D-glucaric acid and metabolism of salicylamide in man: the effect of phenobarbital-produced enzymatic induction. 1977 Jul-Aug Pol J Pharmacol Pharm pmid:905203
Roth B et al. [Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)]. 1977 Padiatr Padol pmid:904946
Rost KL et al. Urinary 6 beta-hydroxycortisol and D-glucaric acid excretion rates are not affected by lansoprazole treatment. 1997 Int J Clin Pharmacol Ther pmid:9021436
Bisio S and Franco G Drinking habits and occupational exposure to xenobiotics: a review. 1995 Jan-Nov G Ital Med Lav pmid:8940655
Sunder-Plassmann G and Hörl WH Safety of intravenous injection of iron saccharate in haemodialysis patients. 1996 Nephrol. Dial. Transplant. pmid:8918625
pmid:8902444
Talafant E et al. Negative feedback control of neonatal serum creatine and increased urinary creatinine excretion after enzyme-inducing drugs. 1977 Pediatr. Res. pmid:887306
Brunelle FM and Verbeeck RK Glucuronidation of diflunisal in liver and kidney microsomes of rat and man. 1996 Xenobiotica pmid:8867997
Lorincz M et al. Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase. 1996 Cytometry pmid:8866216
Silverberg DS et al. Intravenous ferric saccharate as an iron supplement in dialysis patients. 1996 Nephron pmid:8852489
Monarca S et al. Biological monitoring of workers exposed to N-nitrosodiethanolamine in the metal industry. 1996 Environ. Health Perspect. pmid:8834865
Kawasaki H et al. Effect of corticosteroid treatment on bilirubin metabolism in chronic aggressive hepatitis. 1977 Acta Hepatogastroenterol (Stuttg) pmid:883466
Moretti M et al. Biological monitoring of genotoxic hazard in workers of the rubber industry. 1996 Environ. Health Perspect. pmid:8781380
Addyman R et al. Urinary glucaric acid excretion in rheumatoid arthritis: influence of disease activity and disease modifying drugs. 1996 Ann. Rheum. Dis. pmid:8774168
Fujihira E and Whitehouse MW Pathobiodynamics: reduced ascorbate excretion by rats with severe inflammation. 1977 Proc. Soc. Exp. Biol. Med. pmid:877135
Meyer MP et al. A comparison of oral and intravenous iron supplementation in preterm infants receiving recombinant erythropoietin. 1996 J. Pediatr. pmid:8765624
Sung RY et al. Urinary D-glucaric acid excretion in idiopathic neonatal jaundice. 1996 Chin. Med. J. pmid:8758309
Tryba M Epoetin alfa plus autologous blood donation in patients with a low hematocrit scheduled to undergo orthopedic surgery. 1996 Semin. Hematol. pmid:8723577
Mercuriali F Epoetin alfa for autologous blood donation in patients with rheumatoid arthritis and concomitant anemia. 1996 Semin. Hematol. pmid:8723576