Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Rickets, Hypophosphatemic D063730 1 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Anemia, Neonatal D000751 1 associated lipids
Neurocysticercosis D020019 1 associated lipids
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Herzberg M et al. D-Glucaric acid and gamma-glutamyltransferase as indices of hepatic enzyme induction in pregnancy. 1977 Clin. Chem. pmid:13946
Tutor JC et al. Serum copper concentration and hepatic enzyme induction during long-term therapy with anticonvulsants. 1982 Clin. Chem. pmid:6122516
Herzberg M and Wiener MH Increased D-glucaric acid excretion by jaundiced patients. 1978 Clin. Chem. pmid:699285
Oka H et al. Increased urinary excretion of L-xylulose in patients with liver cirrhosis. 1976 Clin. Chim. Acta pmid:1248150
Simmons CJ et al. Urinary D-glucaric acid assay by an improved enzymatic procedure. 1974 Clin. Chim. Acta pmid:4856673
Jung K and Scholz D Increased serum gamma-glutamyltransferase activity in renal transplant recipients: liver damage or microsomal enzyme induction? 1984 Clin. Chim. Acta pmid:6147212
Colombi A et al. Low-pH method for the enzymatic assay of D-glucaric acid in urine. 1983 Clin. Chim. Acta pmid:6851142
Colombi A et al. Influence of sex, age, and smoking habits on the urinary excretion of D-glucaric acid. 1983 Clin. Chim. Acta pmid:6851143
Ideo G et al. Increased urinary D-glucaric acid excretion by children living in an area polluted with tetrachlorodibenzoparadioxin (TCDD). 1982 Clin. Chim. Acta pmid:7074964
Sandle LN and Braganza JM An evaluation of the low-pH enzymatic assay of urinary D-glucaric acid, and its use as a marker of enzyme induction in exocrine pancreatic disease. 1987 Clin. Chim. Acta pmid:3568402
Marsillach J et al. Administration of exogenous erythropoietin beta affects lipid peroxidation and serum paraoxonase-1 activity and concentration in predialysis patients with chronic renal disease and anaemia. 2007 Clin. Exp. Pharmacol. Physiol. pmid:17324148
Hermida J et al. Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment. 2002 Clin. Lab. pmid:12146576
Sirken G et al. Association of different intravenous iron preparations with risk of bacteremia in maintenance hemodialysis patients. 2006 Clin. Nephrol. pmid:17140164
Silverberg DS et al. The correction of anemia in severe resistant heart failure with erythropoietin and intravenous iron prevents the progression of both the heart and the renal failure and markedly reduces hospitalization. 2002 Clin. Nephrol. pmid:12227725
Schwenk MH and Blaustein DA Rapid, high-dose intravenous iron sucrose therapy in 2 Jehovah's Witness patients with severe anemia, iron deficiency and chronic kidney disease. 2004 Clin. Nephrol. pmid:15356968
Ciaccio EI and Fruncillo RJ Urinary excretion of D-glucaric acid by severely burned patients. 1979 Clin. Pharmacol. Ther. pmid:761444
Ohnhaus EE et al. Effect of enzyme induction on plasma lipids using antipyrine, phenobarbital, and rifampicin. 1979 Clin. Pharmacol. Ther. pmid:35298
Wright JH et al. Hepatic enzyme induction patterns and phenothiazine side effects. 1983 Clin. Pharmacol. Ther. pmid:6137306
Perry W and Stamp TC Urinary D-glucaric acid excretion during rifampicin/isoniazid and anticonvulsant enzyme induction. 1984 Clin. Pharmacol. Ther. pmid:6143635
Mustajoki P et al. Rapid normalization of antipyrine oxidation by heme in variegate porphyria. 1992 Clin. Pharmacol. Ther. pmid:1544288
Breimer DD et al. Influence of rifampicin on drug metabolism: differences between hexobarbital and antipyrine. 1977 Clin. Pharmacol. Ther. pmid:849678
Reidenberg P et al. Effects of felbamate on the pharmacokinetics of phenobarbital. 1995 Clin. Pharmacol. Ther. pmid:7554701
Sotaniemi EA et al. Glucaric acid as an indicator of use of enzyme-inducing drugs. 1974 Clin. Pharmacol. Ther. pmid:4150733
Sorrell MF et al. Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis. 1976 Clin. Pharmacol. Ther. pmid:954355
Lai AA et al. Time-course of interaction between carbamazepine and clonazepam in normal man. 1978 Clin. Pharmacol. Ther. pmid:688725
Hopwood JJ and Muller V Biochemical discrimination of Hurler and Scheie syndromes. 1979 Clin. Sci. pmid:38945
Bolton CH et al. Enzyme induction and serum and lipoprotein lipids: a study of glutethimide in normal subjects. 1980 Clin. Sci. pmid:7389270
Yetman AT and Everitt MD The role of iron deficiency in protein-losing enteropathy following the Fontan procedure. 2011 Jul-Aug Congenit Heart Dis pmid:21392262
Reed J et al. The safety of intravenous iron sucrose use in the elderly patient. 2007 Consult Pharm pmid:17658969
Georgopoulos D et al. Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317]. 2005 Crit Care pmid:16277712
van Iperen CE et al. Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients. 2000 Crit. Care Med. pmid:10966249
Corwin HL and Napolitano LM Anemia in the critically ill: do we need to live with it?*. 2014 Crit. Care Med. pmid:25126804
Pieracci FM et al. A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. 2014 Crit. Care Med. pmid:24797376
Vanin S et al. Seasonal variation of trehalose and glycerol concentrations in winter snow-active insects. 2008 Nov-Dec Cryo Letters pmid:19280052
Stein J et al. Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. 2012 Curr Med Res Opin pmid:22181342
Lee ES et al. Comparison of adverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. 2013 Curr Med Res Opin pmid:23252876
Cheng D et al. A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG. 2011 Curr Radiopharm pmid:22191610
Clark SF Iron deficiency anemia: diagnosis and management. 2009 Curr. Opin. Gastroenterol. pmid:19262200
Lorincz M et al. Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase. 1996 Cytometry pmid:8866216
Dornyei A et al. Vanadium(IV,V) complexes of D-saccharic and mucic acids in aqueous solution. 2004 Dalton Trans pmid:15381996
Adjarov D et al. [Clinical significance of D-glucaric of D-glucaric acid determination in the urine of porphyria cutanea tarda patients]. 1985 Dermatol Monatsschr pmid:2861119
Firoz BF et al. Eosinophilic fasciitis secondary to intravenous iron infusions. 2010 Dermatol. Online J. pmid:20492822
Fontés G et al. Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. 2009 Diabetes pmid:19502418
Yi CX et al. A major role for perifornical orexin neurons in the control of glucose metabolism in rats. 2009 Diabetes pmid:19592616
Rombouts K and Marra F Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis. 2010 Dig Dis pmid:20460917
Oyabu H et al. Nonbacterial transformation of bilirubin in bile. 1987 Dig. Dis. Sci. pmid:3608728
Gasche C et al. Sequential treatment of anemia in ulcerative colitis with intravenous iron and erythropoietin. 1999 Digestion pmid:10343140
Abdel-Razeq H et al. Intravenous iron monotherapy for the treatment of non-iron-deficiency anemia in cancer patients undergoing chemotherapy: a pilot study. 2013 Drug Des Devel Ther pmid:24039403
Affrime MB et al. Failure of rifampin to induce the metabolism of clonidine in normal volunteers. 1981 Drug Intell Clin Pharm pmid:7338192
Nakamura Y et al. Decreased valproate level caused by VPA-glucuronidase inhibition by carbapenem antibiotics. 2008 Drug Metab Lett pmid:19356106