Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Rickets, Hypophosphatemic D063730 1 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Anemia, Neonatal D000751 1 associated lipids
Neurocysticercosis D020019 1 associated lipids
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Ohnhaus EE et al. Enzyme induction and renal function in man. 1977 Br J Clin Pharmacol pmid:843422
Ballinger JR et al. Effect of hypoxia on the accumulation of technetium-99m-glucarate and technetium-99m-gluconate by Chinese hamster ovary cells in vitro. 1993 J. Nucl. Med. pmid:8381475
Sandstad O et al. Urinary D-glucaric acid, a marker substance for microsomal enzyme induction. Methodological aspects, responses to alcohol and findings in workers exposed to toluene. 1993 Scand. J. Clin. Lab. Invest. pmid:8378735
Höchli P et al. Repeated continuous administration of low doses of intravenous iron in anemic patients with active rheumatoid arthritis. 1993 Eur. J. Haematol. pmid:8348948
Okuyama T et al. [Measurement and its fluctuation of urinary glucaric acid in newborns]. 1993 Nippon Sanka Fujinka Gakkai Zasshi pmid:8340644
Poon R et al. HPLC determination of D-glucaric acid in human urine. 1993 May-Jun J Anal Toxicol pmid:8336488
Notten WR and Henderson PT The interaction of chemical compounds with the functional state of the liver. II. Estimation of changes in D-glucaric acid synthesis as a method for diagnosing exposure to xenobiotics. 1977 Int Arch Occup Environ Health pmid:832915
Yaoita H et al. Distribution of deoxyglucose and technetium-99m-glucarate in the acutely ischemic myocardium. 1993 J. Nucl. Med. pmid:8326389
Suzuki A et al. Iatrogenic osteomalacia caused by intravenous administration of saccharated ferric oxide. 1993 Am. J. Hematol. pmid:8317471
Webb TE et al. Mechanism of growth inhibition of mammary carcinomas by glucarate and the glucarate: retinoid combination. 1993 Nov-Dec Anticancer Res. pmid:8297119
Brunelle FM and Verbeeck RK Glucuronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity. 1993 Biochem. Pharmacol. pmid:8267644
Hoffmann D [Role of phagocytosis and soluble antibacterial factors in experimental immunization of Locusta migratoria]. 1976 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:821627
Marselos M Genetic variation of drug-metabolizing enzymes in the wistar rat. 1976 Acta Pharmacol Toxicol (Copenh) pmid:821309
Curley RW et al. Activity of D-glucarate analogues: synergistic antiproliferative effects with retinoid in cultured human mammary tumor cells appear to specifically require the D-glucarate structure. 1994 Life Sci. pmid:8190001
Webb TE et al. Pharmacokinetics relevant to the anti-carcinogenic and anti-tumor activities of glucarate and the synergistic combination of glucarate:retinoid in the rat. 1994 Biochem. Pharmacol. pmid:8185680
Newman MA et al. Urinary biological monitoring markers of anticancer drug exposure in oncology nurses. 1994 Am J Public Health pmid:8179062
Ferreira M et al. Determinants of urinary thioethers, D-glucaric acid and mutagenicity after exposure to polycyclic aromatic hydrocarbons assessed by air monitoring and measurement of 1-hydroxypyrene in urine: a cross-sectional study in workers of coke and graphite-electrode-producing plants. 1994 Int Arch Occup Environ Health pmid:8175189
Franco G and Fonte R Advances in evaluating liver response to operating theatre work: urinary D-glucaric acid as an index of effect. 1994 Occup Med (Lond) pmid:8167312
Marselos M and Laitinen M Starvation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa. 1975 Biochem. Pharmacol. pmid:811226
Marselos M et al. Aldehyde dehydrogenase inducibility and ethanol preference in rats. 1975 Med. Biol. pmid:810629