Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
Hemosiderosis D006486 1 associated lipids
Rickets, Hypophosphatemic D063730 1 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Anemia, Neonatal D000751 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Silverberg D et al. The use of androgens in anaemia resistant to erythropoietin and i.v. iron in patients with heart and renal failure. 2004 Nephrol. Dial. Transplant. pmid:15031380
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Okada DR et al. Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate. 2004 J. Nucl. Med. pmid:15073263
Silverstein SB and Rodgers GM Parenteral iron therapy options. 2004 Am. J. Hematol. pmid:15114602
Koller WC et al. Metabolism of glucurolactone to glucarate in Parkinson's disease. 1992 Neurology pmid:1513472
Walaszek Z et al. Mechanisms of lung cancer chemoprevention by D-glucarate. 2004 Chest pmid:15136472
Hanausek M et al. Modulation of biomarkers during chemoprevention of mouse lung tumorigenesis by D-glucarate. 2004 Chest pmid:15136473
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Liu Z et al. 99mTc glucarate high-resolution imaging of drug sensitive and drug resistant human breast cancer xenografts in SCID mice. 2004 Nucl Med Commun pmid:15208499
Pak KY et al. Labeling and stability of radiolabeled antibody fragments by a direct 99mTc-labeling method. 1992 Int J Rad Appl Instrum B pmid:1522021
Liu Z et al. High-resolution imaging with (99m)Tc-glucarate for assessing myocardial injury in rat heart models exposed to different durations of ischemia with reperfusion. 2004 J. Nucl. Med. pmid:15235074
Schröder O et al. A study for the evaluation of safety and tolerability of intravenous high-dose iron sucrose in patients with iron deficiency anemia due to gastrointestinal bleeding. 2004 Z Gastroenterol pmid:15314711
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Wada S et al. [Study of preventive effect of 1-hexylcarbamoyl-5-fluorouracil (HCFU) or combination of HCFU and 2.5-di-O-acetyl-D-glucaro (1-4) (6-3) dilactone (SLA) after preservative operation against bladder cancer]. 1992 Hinyokika Kiyo pmid:1546564
Agarwal R On the nature of proteinuria with acute renal injury in patients with chronic kidney disease. 2005 Am. J. Physiol. Renal Physiol. pmid:15467003
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Tutor-Crespo M et al. Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs. 2004 J Pharm Pharm Sci pmid:15576017
Kanamaru R and Wakui A [Pharmacokinetic studies on fluorinated pyrimidine in cancer cell and tissue]. 1992 Gan To Kagaku Ryoho pmid:1558391
Guz G et al. Elevated cardiac troponin T in hemodialysis patients receiving more intravenous iron sucrose. 2004 Ren Fail pmid:15600258
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Sheashaa H et al. Parenteral iron therapy in treatment of anemia in end-stage renal disease patients: a comparative study between iron saccharate and gluconate. 2005 Nephron Clin Pract pmid:15692217
Liu Y and Reineke TM Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery. 2005 J. Am. Chem. Soc. pmid:15740138
Pecharki GD et al. Effect of sucrose containing iron (II) on dental biofilm and enamel demineralization in situ. 2005 Mar-Apr Caries Res. pmid:15741724
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Cuenca J et al. Role of parenteral iron in the management of anaemia in the elderly patient undergoing displaced subcapital hip fracture repair: preliminary data. 2005 Arch Orthop Trauma Surg pmid:15789233
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Schmittgen TD et al. Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants. 1992 Cancer Chemother. Pharmacol. pmid:1586977
Keven K et al. Combination of intravenous iron sucrose and ascorbic acid in hemodialysis patients. 2005 Kidney Int. pmid:15954940
pmid:16006090
Agarwal R Ironing out the mystery of nephrotoxicity of parenteral iron. 2005 J. Lab. Clin. Med. pmid:16025083