| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemosiderosis | D006486 | 1 associated lipids |
| Rickets, Hypophosphatemic | D063730 | 1 associated lipids |
| Calcium Metabolism Disorders | D002128 | 1 associated lipids |
| Anemia, Neonatal | D000751 | 1 associated lipids |
| Neurocysticercosis | D020019 | 1 associated lipids |
Glucaric acid
Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Glucaric acid?
Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Glucaric acid
PubChem Associated disorders and diseases
What pathways are associated with Glucaric acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Glucaric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Glucaric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Glucaric acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Glucaric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Glucaric acid?
Knock-out
Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Glucaric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Barbieri C et al. | Performance of a Predictive Model for Long-Term Hemoglobin Response to Darbepoetin and Iron Administration in a Large Cohort of Hemodialysis Patients. | 2016 | PLoS ONE | pmid:26939055 |
| pmid:26948581 | ||||
| pmid:26956439 | ||||
| pmid:27001529 | ||||
| Han YM et al. | Comparison of the Efficacies of Parenteral Iron Sucrose and Oral Iron Sulfate for Anemic Patients with Inflammatory Bowel Disease in Korea. | 2016 | Gut Liver | pmid:27021505 |
| pmid:27038710 | ||||
| Gourley GR et al. | The effect of saccharolactone on rat intestinal absorption of bilirubin in the presence of human breast milk. | 1989 | Pediatr. Res. | pmid:2704588 |
| Montano-Pedroso JC et al. | Postoperative intravenously administered iron sucrose versus postoperative orally administered iron to treat post-bariatric abdominoplasty anaemia (ISAPA): the study protocol for a randomised controlled trial. | 2016 | Trials | pmid:27068478 |
| Pasquini R et al. | Urinary excretion of mutagens, thioethers and D-glucaric acid in workers exposed to bitumen fumes. | 1989 | Int Arch Occup Environ Health | pmid:2707871 |
| Liddil JD et al. | Association of lysosomal activity with sensitivity and resistance to tumor necrosis factor in murine L929 cells. | 1989 | Cancer Res. | pmid:2713856 |
| pmid:27141568 | ||||
| pmid:27161817 | ||||
| Zager RA et al. | Combined iron sucrose and protoporphyrin treatment protects against ischemic and toxin-mediated acute renal failure. | 2016 | Kidney Int. | pmid:27165818 |
| Fell LH et al. | Impact of individual intravenous iron preparations on the differentiation of monocytes towards macrophages and dendritic cells. | 2016 | Nephrol. Dial. Transplant. | pmid:27190361 |
| pmid:27197731 | ||||
| pmid:27198564 | ||||
| pmid:27218635 | ||||
| pmid:27218636 | ||||
| pmid:27236130 | ||||
| pmid:27236131 | ||||
| Faber F et al. | Host-mediated sugar oxidation promotes post-antibiotic pathogen expansion. | 2016 | Nature | pmid:27309805 |
| pmid:27312887 | ||||
| pmid:27444324 | ||||
| pmid:27522633 | ||||
| Dwivedi C et al. | Effects of the experimental chemopreventative agent, glucarate, on intestinal carcinogenesis in rats. | 1989 | Carcinogenesis | pmid:2752528 |
| pmid:27540710 | ||||
| Gemici C et al. | Is there any role of intravenous iron for the treatment of anemia in cancer? | 2016 | BMC Cancer | pmid:27542823 |
| Song D et al. | AMD-like retinopathy associated with intravenous iron. | 2016 | Exp. Eye Res. | pmid:27565570 |
| pmid:27576956 | ||||
| Garnham JC et al. | The effect of repeated administration of diftalone on enzyme induction. | 1978 | J. Pharm. Pharmacol. | pmid:27604 |
| pmid:27713040 | ||||
| Abou-Issa H et al. | Synergistic interaction between 13-cis-retinoic acid and glucarate: activity against rat mammary tumor induction and MCF-7 cells. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2783140 |
| pmid:27852236 | ||||
| pmid:27889746 | ||||
| pmid:27915456 | ||||
| Okada S et al. | Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats. | 1989 | Br. J. Cancer | pmid:2803947 |
| Derman R et al. | A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia. | 2017 | Am. J. Hematol. | pmid:28052413 |
| Siest G et al. | [Biological tests as indirect indicators of the activity of drug metabolizing enzymes. Use of glucaric acid and gamma-glutamyltransferase]. | 1977 | Ann. Biol. Clin. (Paris) | pmid:28055 |
| pmid:28063734 | ||||
| pmid:28215716 | ||||
| pmid:28263291 | ||||
| Deng Y et al. | Efficacy of Intravenous Iron Sucrose in Hemodialysis Patients with Restless Legs Syndrome (RLS): A Randomized, Placebo-Controlled Study. | 2017 | Med. Sci. Monit. | pmid:28285317 |
| pmid:28372549 | ||||
| pmid:28482869 | ||||
| pmid:28562517 | ||||
| pmid:28586635 | ||||
| Adjarov D et al. | [Clinical significance of D-glucaric of D-glucaric acid determination in the urine of porphyria cutanea tarda patients]. | 1985 | Dermatol Monatsschr | pmid:2861119 |
| pmid:28656646 | ||||
| Heinemeyer G et al. | D-glucaric acid excretion in critical care patients--comparison with 6 beta-hydroxycortisol excretion and serum gamma-glutamyltranspeptidase activity and relation to multiple drug therapy. | 1986 | Br J Clin Pharmacol | pmid:2868749 |
| Lutz W and Kralkowska E | [Laboratory diagnosis of subclinical forms of chemically-induced liver damage]. | 1986 | Wiad. Lek. | pmid:2873689 |
| pmid:28930667 | ||||
| Tutor JC et al. | Urinary excretion of D-glucaric acid in porphyria cutanea tarda. | 1987 | J. Clin. Chem. Clin. Biochem. | pmid:2895161 |
| Nomoto H et al. | A case of osteomalacia due to deranged mineral balance caused by saccharated ferric oxide and short-bowel syndrome: A case report. | 2017 | Medicine (Baltimore) | pmid:28953654 |
| Tutor JC et al. | Urinary D-glucaric acid and serum hepatic enzyme levels in chronic alcoholics. | 1988 | Clin. Biochem. | pmid:2898981 |
| pmid:29027212 | ||||
| pmid:29138559 | ||||
| Adzharov D et al. | [Effects of preliminary fasting on the development of D-galactosamine-induced acute lesion of the liver in rats]. | 1989 | Biull Eksp Biol Med | pmid:2914170 |
| pmid:29168243 | ||||
| Macfadyen A and Ho KJ | D-glucaro-1,4-lactone: its excretion in the bile and urine and effect on the biliary secretion of beta-glucuronidase after oral administration in rats. | 1989 | Hepatology | pmid:2925160 |
| Abou-Issa HM et al. | Putative metabolites derived from dietary combinations of calcium glucarate and N-(4-hydroxyphenyl)retinamide act synergistically to inhibit the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2967969 |
| Brewster MA | Biomarkers of xenobiotic exposures. | 1988 Jul-Aug | Ann. Clin. Lab. Sci. | pmid:3044268 |
| Kolmodin-Hedman B | Enzyme induction: its relevance for internal exposure and health risks. | 1988 | Int Arch Occup Environ Health | pmid:3049388 |
| Walaszek Z et al. | Dietary glucarate as anti-promoter of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis. | 1986 | Carcinogenesis | pmid:3091283 |
| Dwivedi C et al. | Net glucuronidation in different rat strains: importance of microsomal beta-glucuronidase. | 1987 | FASEB J. | pmid:3115856 |
| Dwivedi C et al. | Effect of dietary calcium glucarate on 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in CD-1 mice. | 1988 Nov-Dec | Cleve Clin J Med | pmid:3147822 |
| Volpi R et al. | [Increased urinary excretion of D-glucaric acid in workers exposed to styrene in reinforced plastics industry]. | 1988 Mar-Apr | Med Lav | pmid:3173231 |
| Mocarelli P et al. | A new method for D-glucaric acid excretion measurement that is suitable for automated instruments. | 1988 | Clin. Chem. | pmid:3180424 |
| Matsushiro T et al. | Effects of diet on glucaric acid concentration in bile and the formation of calcium bilirubinate gallstones. | 1977 | Gastroenterology | pmid:320083 |
| Walaszek Z et al. | Repression by sustained-release beta-glucuronidase inhibitors of chemical carcinogen-mediated induction of a marker oncofetal protein in rodents. | 1988 | J Toxicol Environ Health | pmid:3336058 |
| Apostoli P et al. | [Behavior of urinary D-glucaric acid in occupational exposure to inorganic lead]. | 1987 Sep-Oct | Med Lav | pmid:3447026 |
| Kinouchi T et al. | In vitro intestinal microflora-mediated metabolism of biliary metabolites from 1-nitropyrene-treated rats. | 1987 | Microbiol. Immunol. | pmid:3451027 |
| Ohnhaus EE et al. | Effect of enzyme induction on plasma lipids using antipyrine, phenobarbital, and rifampicin. | 1979 | Clin. Pharmacol. Ther. | pmid:35298 |
| Ohnhaus EE and Park BK | Measurement of urinary 6-beta-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin. | 1979 | Eur. J. Clin. Pharmacol. | pmid:35353 |
| Price DE et al. | The effect of low-dose phenobarbitone on three indices of hepatic microsomal enzyme induction. | 1986 | Br J Clin Pharmacol | pmid:3567022 |
| Sandle LN and Braganza JM | An evaluation of the low-pH enzymatic assay of urinary D-glucaric acid, and its use as a marker of enzyme induction in exocrine pancreatic disease. | 1987 | Clin. Chim. Acta | pmid:3568402 |
| Taccone-Gallucci M et al. | Risk of iron overload and 'hemochromatosis allele(s)' in patients on maintenance hemodialysis. | 1987 | Am. J. Nephrol. | pmid:3578371 |
| Heinemeyer G et al. | Kinetics of hexobarbital and dipyrone in critical care patients receiving high-dose pentobarbital. | 1987 | Eur. J. Clin. Pharmacol. | pmid:3595700 |
| Horváth T et al. | Disorders of biotransformation during the progression of alcoholic liver disease. | 1986 | Acta Med Hung | pmid:3601579 |
| Oyabu H et al. | Nonbacterial transformation of bilirubin in bile. | 1987 | Dig. Dis. Sci. | pmid:3608728 |
| Oredipe OA et al. | Effects of calcium glucarate on the promotion of diethylnitrosamine-initiated altered hepatic foci in rats. | 1987 | Cancer Lett. | pmid:3690519 |
| Kawahara K et al. | Urinary excretion of conjugates of dothiepin and northiaden (mono-N-demethyl-dothiepin) after an oral dose of dothiepin to humans. | 1986 Jan-Mar | Eur J Drug Metab Pharmacokinet | pmid:3720795 |
| Gachályi B et al. | [Effect of alpha methyldopa on the mixed oxygenase system of the liver in man]. | 1979 | Orv Hetil | pmid:372883 |
| Traeger A et al. | Beta-adrenoceptor blocking drugs and cytochrome P-450: the influence of propranolol treatment on caffeine, antipyrine, D-glucaric acid and indocyanine green elimination in patients with hepatic disorders. | 1986 | Int J Clin Pharmacol Res | pmid:3744626 |
| Steinberg KK and Needham LL | A comparison of two methods for quantifying D-glucaric acid. | 1986 Jul-Aug | J Anal Toxicol | pmid:3747452 |
| Nakajima M et al. | A solid-phase substrate of heparanase: its application to assay of human melanoma for heparan sulfate degradative activity. | 1986 | Anal. Biochem. | pmid:3766958 |
| Walaszek Z et al. | Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical carcinogenesis. | 1986 | Cancer Lett. | pmid:3768860 |
| Marsh CA | Biosynthesis of D-glucaric acid in mammals: a free-radical mechanism? | 1986 | Carbohydr. Res. | pmid:3779687 |
| Perry W and Jenkins MV | Note on the enzyme assay for urinary D-glucaric acid and correlation with rifampicin-induced mixed function oxidase activity. | 1986 | Int J Clin Pharmacol Ther Toxicol | pmid:3793294 |
| Balázová E et al. | Antitumor activity of four polymer bound trans-1,2-diaminocyclohexaneplatinum(II)-4-carboxyphtalate complexes tested in different model systems. | 1986 | Neoplasma | pmid:3808121 |
| Couvaris M et al. | Comparative study of the effects of some inducers with or without protein binding properties on bioavailability of isoxazolylpenicillins in rats. | 1986 Jul-Sep | Eur J Drug Metab Pharmacokinet | pmid:3816874 |
| Gachályi B et al. | Pharmacogenetic differences in the inhibitory effect of cimetidine on the metabolism of antipyrine. | 1987 | Eur. J. Clin. Pharmacol. | pmid:3830247 |
| Oxley J et al. | Lack of hepatic enzyme inducing effect of sodium valproate. | 1979 | Br J Clin Pharmacol | pmid:385027 |
| Marsh CA | An enzymatic determination of D-glucaric acid by conversion to pyruvate. | 1985 | Anal. Biochem. | pmid:3893213 |
| Hopwood JJ and Muller V | Biochemical discrimination of Hurler and Scheie syndromes. | 1979 | Clin. Sci. | pmid:38945 |
| Pasquini R et al. | Mutagenicity studies and D-glucaric acid determination in urine of workers exposed to mineral oils. | 1985 | Int Arch Occup Environ Health | pmid:3905625 |
| Micheletti C et al. | [Enzymatic induction during isoniazid therapy (author's transl)]. | 1979 | Pathol. Biol. | pmid:392418 |
| van Soesbergen RM et al. | Bone metabolism in rheumatoid arthritis compared with postmenopausal osteoporosis. | 1986 | Ann. Rheum. Dis. | pmid:3947143 |
| MacNeil ML et al. | A semiautomated procedure for urinary D-glucaric acid using a centrifugal analyzer. | 1986 Jan-Feb | J Anal Toxicol | pmid:3951202 |
| George S et al. | The pharmacokinetics of timegadine and two of its metabolites after multiple oral dosing, and the effects of concomitant administration of ibuprofen. | 1986 | Eur. J. Clin. Pharmacol. | pmid:3956563 |
| Gigon PL and Bickel MH | Interference of UDP-glucuronyltransferase and beta-glucuronidase activity in rat liver microsomes at pH 7.5 with p-nitrophenol and p-nitrophenylglucuronide as substrates. | 1979 | Enzyme | pmid:39749 |