Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Neurocysticercosis D020019 1 associated lipids
Fasciitis D005208 2 associated lipids
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
Hemosiderosis D006486 1 associated lipids
Rickets, Hypophosphatemic D063730 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

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Authors Title Published Journal PubMed Link
Simmons CJ et al. Urinary D-glucaric acid assay by an improved enzymatic procedure. 1974 Clin. Chim. Acta pmid:4856673
Cassimos C et al. Urinary D-glucaric acid excretion in normal and G-6-PD-deficient children with favism. 1974 J. Pediatr. pmid:4826626
Smirne S et al. [Serum gamma-glutamyl-transpeptidase and urinary excretion of D-glucaric acid in epileptic patients treated with anticonvulsants]. 1974 Jul-Aug Riv Neurol pmid:4155805
Murchison LE et al. Effects of anticonvulsants and inactivity on bone disease in epileptics. 1975 Postgrad Med J pmid:1161672
Cassimos C et al. Urinary D-glucaric acid excretion in children with dystonic reactions caused by antiemetic drugs. 1975 J. Pediatr. pmid:1185409
Marselos M et al. Evidence that D-glucaro-1,4-lactone shortens the pharmacological action of drugs being disposed via the bile as glucuronides. 1975 Biochem. Pharmacol. pmid:1191334
Talafant E et al. Glucaric acid excretion as index of hepatic glucuronidation in neonates after phenobarbital treatment. 1975 Pediatr. Res. pmid:1134846
Levy G et al. Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion. 1975 Pediatrics pmid:1134883
Lecamwasam DS Hepatic enzyme induction and its relationship to urinary D-glucaric acid excretion in man. 1975 Br J Clin Pharmacol pmid:1234021
Lecamwasam DS et al. Effect of phenobarbitone on hepatic drug-metabolizing enzymes and urinary D-glucaric acid excretion in man. 1975 Br J Clin Pharmacol pmid:1234506
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Tokola O et al. Hepatic drug-oxidizing enzyme systems and urinary D-glucaric acid excretion in patients with congestive heart failure. 1975 Br J Clin Pharmacol pmid:786355
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Street JC and Chadwick RW Ascorbic acid requirements and metabolism in relation to organochlorine pesticides. 1975 Ann. N. Y. Acad. Sci. pmid:54013
Spencer-Peet J et al. Urinary d-glucaric acid excretion and serum gamma-glutamyl transpeptidase activity in alcoholism. 1975 Br J Addict Alcohol Other Drugs pmid:2272
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Marselos M and Laitinen M Starvation and phenobarbital treatment effects on drug hydroxylation and glucuronidation in the rat liver and small intestinal mucosa. 1975 Biochem. Pharmacol. pmid:811226
Latham AN Effect of in vitro changes in urinary pH on the enzymatic measurement and daily variation in excretion of D-glucaric acid. 1975 J. Pharm. Pharmacol. pmid:239180
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Talafant E et al. Serum gamma-glutamyl transpeptidase activity and urinary D-glucaric acid excretion in newborns in the first week of life. Effects of phenobarbital and nicethamide combination. 1976 Acta Paediatr Scand pmid:11634
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Marselos M Genetic variation of drug-metabolizing enzymes in the wistar rat. 1976 Acta Pharmacol Toxicol (Copenh) pmid:821309
Hoffmann D [Role of phagocytosis and soluble antibacterial factors in experimental immunization of Locusta migratoria]. 1976 C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. pmid:821627
Sorrell MF et al. Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis. 1976 Clin. Pharmacol. Ther. pmid:954355
Roberts C et al. Glutethimide and enzyme induction. 1976 Br Med J pmid:990872
Latham AN et al. Phenobarbitone-induced urinary excretions of D-glucaric acid and 6beta-hydroxycortisol in man. 1976 Can. J. Physiol. Pharmacol. pmid:991005
Furuno K et al. Preventive effect of D-glucarate against renal damage induced by kanamycin. 1976 J. Antibiot. pmid:993134
Furuno K et al. Effect of D-Glucarates on basic antibiotic-induced renal damage in rats. 1976 J. Antibiot. pmid:931801
Mezey E Increased urinary excretion of D-glucaric acid in alcoholism. 1976 Res. Commun. Chem. Pathol. Pharmacol. pmid:1005917
Latham AN and Sweeney GD Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes. 1976 Can. J. Physiol. Pharmacol. pmid:1021219
Düllmann J et al. [Iron storage and metabolism in nacrophages and endothelial cells after intravenous administration of colloidal ferric saccharate in man]. 1976 Verh Anat Ges pmid:1024396
Rycroft D and Daniel JW The excretion of D-glucaric acid in the urine of human volunteers following the administration of disopyramide. 1976 J. Int. Med. Res. pmid:1026531
Ohnhaus EE et al. Enzyme induction and renal function in man. 1977 Br J Clin Pharmacol pmid:843422
Cassimos C et al. Erythrocyte glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice. 1977 Acta Paediatr Scand pmid:868519
Roth B et al. [Excretion of D-glucaric-acid in newborns with non-hemolytic hyperbilirubinemia after phenobarbital treatment (author's transl)]. 1977 Padiatr Padol pmid:904946
Furuno K et al. Influence of dehydration and D-glucarate on distribution and excretion of kanamycin in rats. 1977 Jpn. J. Pharmacol. pmid:916384
Siest G et al. [Biological tests as indirect indicators of the activity of drug metabolizing enzymes. Use of glucaric acid and gamma-glutamyltransferase]. 1977 Ann. Biol. Clin. (Paris) pmid:28055
Herzberg M et al. D-Glucaric acid and gamma-glutamyltransferase as indices of hepatic enzyme induction in pregnancy. 1977 Clin. Chem. pmid:13946
Herzberg M et al. Hepatic microsomal enzyme induction and its evaluation in a clinical laboratory. 1977 Isr. J. Med. Sci. pmid:17578
Breimer DD et al. Influence of rifampicin on drug metabolism: differences between hexobarbital and antipyrine. 1977 Clin. Pharmacol. Ther. pmid:849678
Weiersmüller A et al. The influence of prednisolone on hepatic function in normal subjects. Effects on galactose elimination capacity, sulfobromophthalein transport maximum and storage capacity, and D-glucaric acid output. 1977 Am J Dig Dis pmid:857663
Notten WR and Henderson PT The interaction of chemical compounds with the functional state of the liver. II. Estimation of changes in D-glucaric acid synthesis as a method for diagnosing exposure to xenobiotics. 1977 Int Arch Occup Environ Health pmid:832915
Arató M and Varadi A On the possible role of enzyme induction in cases of resistancy to chlorpromazine treatment. 1977 Pharmakopsychiatr Neuropsychopharmakol pmid:616930