Glucaric acid

Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Glucaric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glucaric acid?

Glucaric acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glucaric acid

MeSH term MeSH ID Detail
Anemia, Neonatal D000751 1 associated lipids
Neurocysticercosis D020019 1 associated lipids
Telangiectasia, Hereditary Hemorrhagic D013683 1 associated lipids
Hemosiderosis D006486 1 associated lipids
Rickets, Hypophosphatemic D063730 1 associated lipids
Calcium Metabolism Disorders D002128 1 associated lipids
Gilbert Disease D005878 2 associated lipids
Fasciitis D005208 2 associated lipids
Restless Legs Syndrome D012148 2 associated lipids
von Willebrand Diseases D014842 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Glucaric acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Glucaric acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glucaric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glucaric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glucaric acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glucaric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glucaric acid?

Knock-out

Knock-out are used in the study 'Evolution-guided optimization of biosynthetic pathways.' (Raman S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glucaric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Kochhar PK et al. Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial. 2013 J. Obstet. Gynaecol. Res. pmid:22925176
Lee ES et al. Comparison of adverse event profile of intravenous iron sucrose and iron sucrose similar in postpartum and gynecologic operative patients. 2013 Curr Med Res Opin pmid:23252876
Bhattacharya S et al. D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. 2013 Toxicol. Appl. Pharmacol. pmid:23261973
Moore KL et al. Uncommon adverse effect of a common medication. 2013 Tidsskr. Nor. Laegeforen. pmid:23344600
Froessler B et al. Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial. 2013 J. Matern. Fetal. Neonatal. Med. pmid:23130909
Kumbasar A et al. The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients. 2012 Sep-Oct J. Nephrol. pmid:22307439
Sricholpech M et al. Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. 2012 J. Biol. Chem. pmid:22573318
Smith AA et al. The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. 2012 PLoS Comput. Biol. pmid:22693442
De Sousa A and Kalra G Drug therapy of attention deficit hyperactivity disorder: current trends. 2012 Mens Sana Monogr pmid:22654382
Ernst MC et al. Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance. 2012 Endocrinology pmid:22186410
Kamanna VS et al. Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. 2012 Am. J. Nephrol. pmid:22212390
Stein J et al. Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator. 2012 Curr Med Res Opin pmid:22181342
Rashid K et al. Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. 2012 Free Radic. Res. pmid:22239106
Ichii H et al. Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes. 2012 Am. J. Nephrol. pmid:22722756
Pfenniger A et al. Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia. 2012 J Perinat Med pmid:22752771
da Silva Krause M et al. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. 2012 J. Endocrinol. pmid:22761278
Galindo P et al. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. 2012 PLoS ONE pmid:22427863
Conner TA et al. Effect of intravenous vitamin C on cytokine activation and oxidative stress in end-stage renal disease patients receiving intravenous iron sucrose. 2012 Biometals pmid:22706571
Isnardi V et al. Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5? 2012 Nucl. Med. Biol. pmid:23084044
Xia B et al. A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. 2012 Mol. Pharm. pmid:23033922