Oxoadipic acid

Oxoadipic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 284 references associated with Oxoadipic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Oxoadipic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Oxoadipic acid

MeSH term MeSH ID Detail
Maple Syrup Urine Disease D008375 5 associated lipids
Total 1

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Oxoadipic acid

Download all related citations
Per page 10 20 50 100 | Total 72
Authors Title Published Journal PubMed Link
Goncalves RL et al. Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex. 2016 Free Radic. Biol. Med. pmid:26708453
Shibata K et al. High-performance liquid chromatographic method for profiling 2-oxo acids in urine and its application in evaluating vitamin status in rats. 2016 Biosci. Biotechnol. Biochem. pmid:26745680
Wagner T et al. A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase). 2014 Biochem. J. pmid:24171907
Shibata K et al. Pantothenic acid deficiency may increase the urinary excretion of 2-oxo acids and nicotinamide catabolites in rats. 2013 J. Nutr. Sci. Vitaminol. pmid:24477247
Gabriel I et al. Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug. 2013 FEMS Yeast Res. pmid:23107040
Reitman ZJ et al. Enzyme redesign guided by cancer-derived IDH1 mutations. 2012 Nat. Chem. Biol. pmid:23001033
Danhauser K et al. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. 2012 Am. J. Hum. Genet. pmid:23141293
Sonnenschein N et al. A network perspective on metabolic inconsistency. 2012 BMC Syst Biol pmid:22583819
Haferkamp I and Schmitz-Esser S The plant mitochondrial carrier family: functional and evolutionary aspects. 2012 Front Plant Sci pmid:22639632
Parthasarathy A et al. Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acid. 2011 Biochemistry pmid:21434666
Shibata K et al. Fluorometric determination of 2-oxoadipic acid, a common metabolite of tryptophan and lysine, by high-performance liquid chromatography with pre-chemical derivatization. 2011 Biosci. Biotechnol. Biochem. pmid:21228461
Li JV et al. Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. 2011 Parasit Vectors pmid:21929782
Kaster AK et al. More than 200 genes required for methane formation from Hâ‚‚ and COâ‚‚ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. 2011 Archaea pmid:21559116
Connor SC et al. Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. 2010 Mol Biosyst pmid:20567778
Taylor NL et al. Analysis of the rice mitochondrial carrier family reveals anaerobic accumulation of a basic amino acid carrier involved in arginine metabolism during seed germination. 2010 Plant Physiol. pmid:20720170
Lin Y et al. Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. 2009 Biochemistry pmid:19530703
Tomita T et al. Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus. 2009 Proteins pmid:18831049
Niimi M et al. Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. 2009 J. Biomed. Sci. pmid:19825180
Han Q et al. Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. 2008 Biosci. Rep. pmid:18620547
Azuma M et al. Adenine nucleotide translocator transports haem precursors into mitochondria. 2008 PLoS ONE pmid:18728780
Yamamoto T and Eguchi T Thiahomoisocitrate: a highly potent inhibitor of homoisocitrate dehydrogenase involved in the alpha-aminoadipate pathway. 2008 Bioorg. Med. Chem. pmid:18086528
Bunik VI and Degtyarev D Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. 2008 Proteins pmid:18004749
Castrillo JI et al. Growth control of the eukaryote cell: a systems biology study in yeast. 2007 J. Biol. pmid:17439666
Montero-Morán GM et al. Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans. 2007 Biochemistry pmid:17429948
Lin Y et al. Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae. 2007 Biochemistry pmid:17223711
Cakir T et al. Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. 2007 Theor Biol Med Model pmid:18070347
Xu H et al. Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae. 2007 Biochemistry pmid:17542618
Schwimmer C et al. Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. 2005 J. Biol. Chem. pmid:15975925
Valmaseda EM et al. Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase. 2005 Mol. Genet. Genomics pmid:16049680
Schulze-Bergkamen A et al. Quantitative acylcarnitine profiling in peripheral blood mononuclear cells using in vitro loading with palmitic and 2-oxoadipic acids: biochemical confirmation of fatty acid oxidation and organic acid disorders. 2005 Pediatr. Res. pmid:16183823
Miyazaki T et al. alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus. 2004 Microbiology (Reading, Engl.) pmid:15256574
Miyazaki J et al. Characterization of homoisocitrate dehydrogenase involved in lysine biosynthesis of an extremely thermophilic bacterium, Thermus thermophilus HB27, and evolutionary implication of beta-decarboxylating dehydrogenase. 2003 J. Biol. Chem. pmid:12427751
Kroumova AB and Wagner GJ Different elongation pathways in the biosynthesis of acyl groups of trichome exudate sugar esters from various solanaceous plants. 2003 Planta pmid:12687369
White AK and Metcalf WW Isolation and biochemical characterization of hypophosphite/2-oxoglutarate dioxygenase. A novel phosphorus-oxidizing enzyme from Psuedomonas stutzeri WM88. 2002 J. Biol. Chem. pmid:12161433
Lee JS et al. A Korean girl with alpha-aminoadipic and alpha-ketoadipic aciduria accompanied with elevation of 2-hydroxyglutarate and glutarate. 2001 J. Inherit. Metab. Dis. pmid:11596655
Fiermonte G et al. Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. 2001 J. Biol. Chem. pmid:11083877
Lee HJ et al. Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. 2001 J. Biol. Chem. pmid:11279000
Fu X et al. Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids. 2001 J. Chromatogr. B Biomed. Sci. Appl. pmid:11482739
Palmieri L et al. Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. 2001 J. Biol. Chem. pmid:11013234
Barshop BA et al. Kearns-Sayre syndrome presenting as 2-oxoadipic aciduria. 2000 Mol. Genet. Metab. pmid:10655159
Sewell AC et al. Normal kynurenine metabolism in 2-oxoadipic aciduria. 1999 J. Inherit. Metab. Dis. pmid:10604155
Howell DM et al. Alpha-keto acid chain elongation reactions involved in the biosynthesis of coenzyme B (7-mercaptoheptanoyl threonine phosphate) in methanogenic Archaea. 1998 Biochemistry pmid:9665716
Lukacin R and Britsch L Identification of strictly conserved histidine and arginine residues as part of the active site in Petunia hybrida flavanone 3beta-hydroxylase. 1997 Eur. J. Biochem. pmid:9395322
Bunik VI and Pavlova OG Inactivation of alpha-ketoglutarate dehydrogenase during oxidative decarboxylation of alpha-ketoadipic acid. 1993 FEBS Lett. pmid:8495733
Darmaun D et al. Determination of glutamine and alpha-ketoglutarate concentration and specific activity in plasma using high-performance liquid chromatography. 1993 J. Chromatogr. pmid:8106589
Mori M and Shiio I Synergistic inhibition of phosphoenolpyruvate carboxylase by aspartate and 2-oxoglutarate in Brevibacterium flavum. 1985 J. Biochem. pmid:4093449
Osmani SA and Scrutton MC The sub-cellular localisation and regulatory properties of pyruvate carboxylase from Rhizopus arrhizus. 1985 Eur. J. Biochem. pmid:3971971
Majamaa K et al. The 2-oxoglutarate binding site of prolyl 4-hydroxylase. Identification of distinct subsites and evidence for 2-oxoglutarate decarboxylation in a ligand reaction at the enzyme-bound ferrous ion. 1984 Eur. J. Biochem. pmid:6321169
Hine DG and Tanaka K Capillary gas chromatographic/mass spectrometric analysis of abnormal metabolites in hypoglycin-treated rat urine. 1984 Biomed. Mass Spectrom. pmid:6478044
Stafeeva OA et al. [Sulfhydryl groups of alpha-ketoglutarate dehydrogenase from pigeon breast muscle]. 1982 Biokhimiia pmid:7126703
Musílková M et al. Accumulation of 2-oxo acids in mutants of Aspergillus niger requiring lysine. 1980 Folia Microbiol. (Praha) pmid:6774936
Suda T et al. Developmental changes in the enzymatic capacity for reduction and oxidation of alpha-ketoadipate in rat liver, heart, kidney, and brain. 1978 Pediatr. Res. pmid:652411
Suda T et al. Subcellular localization and tissue distribution of alpha-ketoadipate reduction and oxidation in the rat. 1977 Biochem. Biophys. Res. Commun. pmid:901489
Suda T et al. Purification and properties of alpha-ketoadipate reductase, a newly discovered enzyme from human placenta. 1976 Arch. Biochem. Biophys. pmid:185965
Plaut GW et al. Substrate activity of structural analogs of isocitrate for isocitrate dehydrogenases from bovine heart. 1975 Biochemistry pmid:238563
Ornston MK and Ornston LN The regulation of the -ketoadipate pathway in Pseudomonas acidovorans and Pseudomonas testosteroni. 1972 J. Gen. Microbiol. pmid:4657135
Strassman M and Ceci LN Enzymatic formation of alpha-ketoadipic acid from homoisocitric acid. 1965 J. Biol. Chem. pmid:4284830
WEBER MA et al. BIOSYNTHESIS OF ALPHA-KETOADIPIC ACID BY EXTRACTS OF BAKER'S YEAST. 1964 Arch. Biochem. Biophys. pmid:14163891
pmid:
pmid:16087053
pmid:25860818
pmid:22001859
pmid:21982920
pmid:21840471
pmid:21813504
pmid:18321070
pmid:17116397
pmid:12126930
pmid:28429309
pmid:16233253
pmid:17234850
pmid:28435050