2R-hydroxy-oleic acid

2r-hydroxy-oleic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 17 references associated with 2R-hydroxy-oleic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2R-hydroxy-oleic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2R-hydroxy-oleic acid

MeSH term MeSH ID Detail
Neoplasms D009369 13 associated lipids
Lung Neoplasms D008175 171 associated lipids
Glioma D005910 112 associated lipids
Sphingolipidoses D013106 2 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Total 5

All references with 2R-hydroxy-oleic acid

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Per page 10 20 | Total 17
Authors Title Published Journal PubMed Link
Borchert GH et al. 2-hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18296566
Terés S et al. Normalization of sphingomyelin levels by 2-hydroxyoleic acid induces autophagic cell death of SF767 cancer cells. 2012 Autophagy pmid:22892762
Martin ML et al. The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid. 2013 Biochim. Biophys. Acta pmid:23360770
Lladó V et al. Regulation of the cancer cell membrane lipid composition by NaCHOleate: effects on cell signaling and therapeutical relevance in glioma. 2014 Biochim. Biophys. Acta pmid:24525074
Piotto S et al. The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes. 2014 Biochim. Biophys. Acta pmid:24463068
Piotto S et al. Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets. 2014 Biochim. Biophys. Acta pmid:24412218
Alemany R et al. 2-hydroxyoleic acid: a new hypotensive molecule. 2004 Hypertension pmid:14662651
Cerezo J et al. Atomistic molecular dynamics simulations of the interactions of oleic and 2-hydroxyoleic acids with phosphatidylcholine bilayers. 2011 J Phys Chem B pmid:21882864
Alemany R et al. Antihypertensive action of 2-hydroxyoleic acid in SHRs via modulation of the protein kinase A pathway and Rho kinase. 2006 J. Lipid Res. pmid:16687663
Martin ML et al. Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells. 2013 J. Lipid Res. pmid:23471028

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