2R-hydroxy-oleic acid

2r-hydroxy-oleic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 17 references associated with 2R-hydroxy-oleic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2R-hydroxy-oleic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2R-hydroxy-oleic acid

MeSH term MeSH ID Detail
Neoplasms D009369 13 associated lipids
Lung Neoplasms D008175 171 associated lipids
Glioma D005910 112 associated lipids
Sphingolipidoses D013106 2 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Total 5

All references with 2R-hydroxy-oleic acid

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Per page 10 20 | Total 17
Authors Title Published Journal PubMed Link
Alemany R et al. 2-hydroxyoleic acid: a new hypotensive molecule. 2004 Hypertension pmid:14662651
Barceló F et al. The hypotensive drug 2-hydroxyoleic acid modifies the structural properties of model membranes. 2004 Jul-Aug Mol. Membr. Biol. pmid:15371015
Alemany R et al. Antihypertensive action of 2-hydroxyoleic acid in SHRs via modulation of the protein kinase A pathway and Rho kinase. 2006 J. Lipid Res. pmid:16687663
Prades J et al. Effects of 2-hydroxyoleic acid on the structural properties of biological and model plasma membranes. 2008 Mol. Membr. Biol. pmid:17852735
Borchert GH et al. 2-hydroxyoleic acid affects cardiomyocyte [Ca2+]i transient and contractility in a region-dependent manner. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18296566
Lladó V et al. Pivotal role of dihydrofolate reductase knockdown in the anticancer activity of 2-hydroxyoleic acid. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19666584
Cerezo J et al. Atomistic molecular dynamics simulations of the interactions of oleic and 2-hydroxyoleic acids with phosphatidylcholine bilayers. 2011 J Phys Chem B pmid:21882864
Barceló-Coblijn G et al. Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:22106271
Terés S et al. 2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22586083
Prades J et al. Effect of a 2-hydroxylated fatty acid on cholesterol-rich membrane domains. 2012 Mol. Membr. Biol. pmid:22830943

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