PA(18:1(9Z)/18:1(9Z))

PA(18:1(9Z)/18:1(9Z)) is a lipid of Glycerophospholipids (GP) class. The involved functions are known as adenylate cyclase activity, inhibitors, Drug Interactions, Membrane Fluidity and Force. Pa(18:1(9z)/18:1(9z)) often locates in Cell membrane, Tissue membrane, Epidermis, Connective Tissue and Back. The associated genes with PA(18:1(9Z)/18:1(9Z)) are growth promoting activity and RAF1 gene. The related lipids are Phosphatidic Acid, Lysophospholipids, lysophosphatidic acid, Lysophosphatidylcholines and dioleoyl phosphate.

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Introduction

To understand associated biological information of PA(18:1(9Z)/18:1(9Z)), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PA(18:1(9Z)/18:1(9Z))?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with PA(18:1(9Z)/18:1(9Z))

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PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with PA(18:1(9Z)/18:1(9Z))?

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What functions are associated with PA(18:1(9Z)/18:1(9Z))?


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What lipids are associated with PA(18:1(9Z)/18:1(9Z))?

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What genes are associated with PA(18:1(9Z)/18:1(9Z))?

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What common seen animal models are associated with PA(18:1(9Z)/18:1(9Z))?

There are no associated biomedical information in the current reference collection.

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All references with PA(18:1(9Z)/18:1(9Z))

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Authors Title Published Journal PubMed Link
Mizuno S et al. Dioleoyl-phosphatidic acid selectively binds to α-synuclein and strongly induces its aggregation. 2017 FEBS Lett. pmid:28186641
Rivero Berti I et al. Delivery of fluorophores by calcium phosphate-coated nanoliposomes and interaction with Staphylococcus aureus biofilms. 2016 Colloids Surf B Biointerfaces pmid:26954088
Chen YF et al. Differential dependencies on [Ca2+] and temperature of the monolayer spontaneous curvatures of DOPE, DOPA and cardiolipin: effects of modulating the strength of the inter-headgroup repulsion. 2015 Soft Matter pmid:25907686
Li J et al. Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor. 2012 J Control Release pmid:22056915
Roberts MF et al. Phospholipid reorientation at the lipid/water interface measured by high resolution 31P field cycling NMR spectroscopy. 2009 Biophys. J. pmid:19580751
Lamberson ER et al. Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures. 2009 J Phys Chem B pmid:19243147
Chang YJ et al. Dioleoyl phosphatidic acid induces morphological changes through an endogenous LPA receptor in C6 glioma cells. 2008 Arch. Pharm. Res. pmid:18481020
Stöckl M et al. Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains. 2008 J. Mol. Biol. pmid:18082181
Andre G et al. Probing the interaction forces between hydrophobic peptides and supported lipid bilayers using AFM. 2007 Nov-Dec J. Mol. Recognit. pmid:17891753
Kapralov AA et al. The hierarchy of structural transitions induced in cytochrome c by anionic phospholipids determines its peroxidase activation and selective peroxidation during apoptosis in cells. 2007 Biochemistry pmid:18004876
Hamouda AK et al. Assessing the lipid requirements of the Torpedo californica nicotinic acetylcholine receptor. 2006 Biochemistry pmid:16566607
Masum SM et al. Effect of positively charged short peptides on stability of cubic phases of monoolein/dioleoylphosphatidic acid mixtures. 2005 Langmuir pmid:15924452
Kooijman EE et al. Spontaneous curvature of phosphatidic acid and lysophosphatidic acid. 2005 Biochemistry pmid:15697235
Kooijman EE et al. What makes the bioactive lipids phosphatidic acid and lysophosphatidic acid so special? 2005 Biochemistry pmid:16363814
Li SJ and Yamazaki M Low concentration of dioleoylphosphatidic acid induces an inverted hexagonal (H II) phase transition in dipalmitoleoylphosphatidylethanolamine membranes. 2004 Biophys. Chem. pmid:15059667
Niedernberg A et al. Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63. 2003 Cell. Signal. pmid:12618218
Takahashi T et al. Phosphatidic acid has a potential to promote hair growth in vitro and in vivo, and activates mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in hair epithelial cells. 2003 J. Invest. Dermatol. pmid:12925199
Yan L et al. tBid forms a pore in the liposome membrane. 2003 FEBS Lett. pmid:14675771
Tanaka A and Hoshino E Similarities between the thermal inactivation kinetics of Bacillus amyloliquefaciens alpha-amylase in an aqueous solution of sodium dodecyl sulphate and the kinetics in the solution of anionic-phospholipid vesicles. 2003 Biotechnol. Appl. Biochem. pmid:12816534
Mayer PT et al. A hydrophobicity scale for the lipid bilayer barrier domain from peptide permeabilities: nonadditivities in residue contributions. 2003 Biochemistry pmid:12578376
Shanley TP et al. The serine/threonine phosphatase, PP2A: endogenous regulator of inflammatory cell signaling. 2001 J. Immunol. pmid:11145674
Li SJ et al. Effect of electrostatic interactions on phase stability of cubic phases of membranes of monoolein/dioleoylphosphatidic acid mixtures. 2001 Biophys. J. pmid:11463640
Baenziger JE et al. Effect of membrane lipid composition on the conformational equilibria of the nicotinic acetylcholine receptor. 2000 J. Biol. Chem. pmid:10625607
Kostrzewa A et al. Membrane location of spin-labeled cytochrome c determined by paramagnetic relaxation agents. 2000 Biochemistry pmid:10821679
Holopainen JM et al. Evidence for the extended phospholipid conformation in membrane fusion and hemifusion. 1999 Biophys. J. pmid:10096906
Dalton KA et al. Anionic phospholipids decrease the rate of slippage on the Ca(2+)-ATPase of sarcoplasmic reticulum. 1999 Biochem. J. pmid:10455031
Raines DE and Krishnan NS Agonist binding and affinity state transitions in reconstituted nicotinic acetylcholine receptors revealed by single and sequential mixing stopped-flow fluorescence spectroscopies. 1998 Biochim. Biophys. Acta pmid:9814855
Dalton KA et al. Anionic lipids and accumulation of Ca2+ by a Ca(2+)-ATPase. 1998 Biochem. Soc. Trans. pmid:9765953
Hixon MS et al. Calcium-dependent and -independent interfacial binding and catalysis of cytosolic group IV phospholipase A2. 1998 Biochemistry pmid:9622504
Oja CD et al. Influence of dose on liposome clearance: critical role of blood proteins. 1996 Biochim. Biophys. Acta pmid:8652601
Ferguson JE and Hanley MR Phosphatidic acid and lysophosphatidic acid stimulate receptor-regulated membrane currents in the Xenopus laevis oocyte. 1992 Arch. Biochem. Biophys. pmid:1379791
McCarthy MP and Moore MA Effects of lipids and detergents on the conformation of the nicotinic acetylcholine receptor from Torpedo californica. 1992 J. Biol. Chem. pmid:1560000
Spruijt RB et al. Interaction of non-enveloped plant viruses and their viral coat proteins with phospholipid vesicles. 1991 Biochim. Biophys. Acta pmid:2059653
Lebeau L et al. Two-dimensional crystallization of DNA gyrase B subunit on specifically designed lipid monolayers. 1990 FEBS Lett. pmid:2163898
Lin YP and Carman GM Kinetic analysis of yeast phosphatidate phosphatase toward Triton X-100/phosphatidate mixed micelles. 1990 J. Biol. Chem. pmid:2152917
McGhee JG and Shoback DM Effects of phosphatidic acid on parathyroid hormone release, intracellular free Ca2+, and inositol phosphates in dispersed bovine parathyroid cells. 1990 Endocrinology pmid:2153532
Sun J and Petersheim M Lanthanide(III)-phosphatidic acid complexes: binding site heterogeneity and phase separation. 1990 Biochim. Biophys. Acta pmid:2110832
Woźniak M et al. The influence of phosphatidate bilayers on pig heart AMP deaminase. Crucial role of pH-dependent lipid-phase transition. 1988 Biochem. J. pmid:3214434
Smaal EB et al. 2H-NMR, 31P-NMR and DSC characterization of a novel lipid organization in calcium-dioleoylphosphatidate membranes. Implications for the mechanism of the phosphatidate calcium transmembrane shuttle. 1987 Biochim. Biophys. Acta pmid:3814595
Smaal EB et al. Consequences of the interaction of calcium with dioleoylphosphatidate-containing model membranes: calcium-membrane and membrane-membrane interactions. 1987 Biochim. Biophys. Acta pmid:3099843
Nicolay K et al. Ethylene glycol causes acyl chain disordering in liquid-crystalline, unsaturated phospholipid model membranes, as measured by 2H NMR. 1986 FEBS Lett. pmid:3803574
Houslay MD et al. Acidic phospholipid species inhibit adenylate cyclase activity in rat liver plasma membranes. 1986 Biochem. J. pmid:3741383
Smaal EB et al. Consequences of the interaction of calcium with dioleoylphosphatidate-containing model membranes: changes in membrane permeability. 1986 Biochim. Biophys. Acta pmid:3730389
Smaal EB et al. Essential adaptation of the calcium influx assay into liposomes with entrapped arsenazo III for studies on the possible calcium translocating properties of acidic phospholipids. 1985 Biochim. Biophys. Acta pmid:3924100
Nayar R et al. Phosphatidic acid as a calcium ionophore in large unilamellar vesicle systems. 1984 Biochim. Biophys. Acta pmid:6435674
Miner VW and Prestegard JH Structure of divalent cation-phosphatidic acid complexes as determined by 31P-NMR. 1984 Biochim. Biophys. Acta pmid:6743656
Brasseur R et al. Mode of organization of lipid aggregates: a conformational analysis. 1984 Biosci. Rep. pmid:6547066
Farren SB et al. Polymorphic phase preferences of phosphatidic acid: A 31P and 2H NMR study. 1983 Biochem. Biophys. Res. Commun. pmid:6838577
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