| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteriosclerosis | D001161 | 86 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
Total
2
POV-PC
POV-PC is a lipid of Glycerophospholipids (GP) class. Pov-pc is associated with abnormalities such as Atherosclerosis, Coronary Artery Disease, BOSLEY-SALIH-ALORAINY SYNDROME, Coronary Arteriosclerosis and Hypercholesterolemia. The involved functions are known as Metabolic Inhibition, Binding (Molecular Function), Tissue Adhesions, Oxidation and Cell Communication. Pov-pc often locates in Endothelium, Arterial system, Membrane, Cell surface and Plasma membrane. The associated genes with POV-PC are PCDH8 gene, CS1 peptide, MYOZ2 gene, SLC33A1 gene and Genes, Reporter. The related lipids are oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine, 1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphorylcholine, oxidized lipid, LYSO-PC and Lipopolysaccharides. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of POV-PC, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with POV-PC?
POV-PC is suspected in BOSLEY-SALIH-ALORAINY SYNDROME, Coronary Arteriosclerosis, Atherosclerosis, Coronary Artery Disease, Hypercholesterolemia, Hereditary pancreatitis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with POV-PC
PubChem Associated disorders and diseases
What pathways are associated with POV-PC
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with POV-PC?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with POV-PC?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with POV-PC?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with POV-PC?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with POV-PC?
Knock-out
Knock-out are used in the study 'Oxidized phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration.' (Cherepanova OA et al., 2009).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with POV-PC
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ayee MAA et al. | Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids. | 2017 | Biophys. J. | pmid:28122218 |
| Yeon SH et al. | Oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages. | 2017 | J. Leukoc. Biol. | pmid:27256568 |
| Yan FX et al. | The oxidized phospholipid POVPC impairs endothelial function and vasodilation via uncoupling endothelial nitric oxide synthase. | 2017 | J. Mol. Cell. Cardiol. | pmid:28870504 |
| Ademowo OS et al. | Phospholipid oxidation and carotenoid supplementation in Alzheimer's disease patients. | 2017 | Free Radic. Biol. Med. | pmid:28315450 |
| Barbour SE and Ramanadham S | Analyses of Calcium-Independent Phospholipase Abeta (iPLAβ) in Biological Systems. | 2017 | Meth. Enzymol. | pmid:28063488 |
| Vogl F et al. | Role of protein kinase C δ in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages. | 2016 | Biochim. Biophys. Acta | pmid:26707247 |
| Stokes CA et al. | Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes. | 2016 | Mucosal Immunol | pmid:26906404 |
| Brameshuber M et al. | Oxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms. | 2016 | Biophys. J. | pmid:26745423 |
| Vinetti G et al. | Supervised exercise training reduces oxidative stress and cardiometabolic risk in adults with type 2 diabetes: a randomized controlled trial. | 2015 | Sci Rep | pmid:25783765 |
| Bretscher P et al. | Phospholipid oxidation generates potent anti-inflammatory lipid mediators that mimic structurally related pro-resolving eicosanoids by activating Nrf2. | 2015 | EMBO Mol Med | pmid:25770125 |