PAz-PC

PAz-PC is a lipid of Glycerophospholipids (GP) class. Paz-pc is associated with abnormalities such as Gigantism. The involved functions are known as pore complex location biogenesis, Extravasation, Leak NOS, Process and Physiologic Organization. Paz-pc often locates in Membrane, Tissue membrane, Lipid Bilayers, Mitochondrial Membranes and Protoplasm. The associated genes with PAz-PC are oxytocin, 1-penicillamyl-Leu(2)-. The related lipids are Cardiolipins, oxidized lipid, 1-palmitoyl-2-oleoylphosphatidylethanolamine and DOPE.

Cross Reference

Introduction

To understand associated biological information of PAz-PC, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PAz-PC?

PAz-PC is suspected in Gigantism and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PAz-PC

MeSH term MeSH ID Detail
Leukemia D007938 74 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with PAz-PC

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PAz-PC?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PAz-PC?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PAz-PC?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PAz-PC?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PAz-PC?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with PAz-PC

Download all related citations
Per page 10 20 | Total 15
Authors Title Published Journal PubMed Link
Rosa R et al. Hydroperoxide and carboxyl groups preferential location in oxidized biomembranes experimentally determined by small angle X-ray scattering: Implications in membrane structure. 2018 Biochim Biophys Acta Biomembr pmid:29852123
Moleiro LH et al. Permeability modes in fluctuating lipid membranes with DNA-translocating pores. 2017 Adv Colloid Interface Sci pmid:28735883
Mendes Ferreira T et al. Acyl Chain Disorder and Azelaoyl Orientation in Lipid Membranes Containing Oxidized Lipids. 2016 Langmuir pmid:27260273
Lidman M et al. The oxidized phospholipid PazePC promotes permeabilization of mitochondrial membranes by Bax. 2016 Biochim. Biophys. Acta pmid:26947183
Kinnunen PK et al. Formation of lipid/peptide tubules by IAPP and temporin B on supported lipid membranes. 2015 Soft Matter pmid:26575388
Makky A and Tanaka M Impact of lipid oxidization on biophysical properties of model cell membranes. 2015 J Phys Chem B pmid:25870900
Kawai C et al. Not only oxidation of cardiolipin affects the affinity of cytochrome C for lipid bilayers. 2014 J Phys Chem B pmid:25247479
Wallgren M et al. The oxidized phospholipid PazePC modulates interactions between Bax and mitochondrial membranes. 2012 Biochim. Biophys. Acta pmid:22705638
Wang Y et al. Oxidized phospholipid based pH sensitive micelles for delivery of anthracyclines to resistant leukemia cells in vitro. 2012 Int J Pharm pmid:22037443
Sorrentino R et al. The activation of liver X receptors inhibits toll-like receptor-9-induced foam cell formation. 2010 J. Cell. Physiol. pmid:20049870