McHale-Owen H and Bate C |
Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-β oligomers. |
2018 |
Biochim. Biophys. Acta |
pmid:29247837
|
Liu N et al. |
Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway. |
2017 |
Org. Lett. |
pmid:28605916
|
Liddle E et al. |
In vitro kinetic study of the squalestatin tetraketide synthase dehydratase reveals the stereochemical course of a fungal highly reducing polyketide synthase. |
2017 |
Chem. Commun. (Camb.) |
pmid:28106181
|
Lanterna C et al. |
The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice. |
2016 |
Cancer Immunol. Immunother. |
pmid:27520505
|
Bonsch B et al. |
Identification of genes encoding squalestatin S1 biosynthesis and in vitro production of new squalestatin analogues. |
2016 |
Chem. Commun. (Camb.) |
pmid:27056201
|
Pastar I et al. |
Skin Metabolite, Farnesyl Pyrophosphate, Regulates Epidermal Response to Inflammation, Oxidative Stress, and Migration. |
2016 |
J. Cell. Physiol. |
pmid:26916741
|
Rondini EA et al. |
Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat Hepatocytes. |
2016 |
J. Pharmacol. Exp. Ther. |
pmid:27225895
|
Pant A and Kocarek TA |
Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes. |
2016 |
Drug Metab. Dispos. |
pmid:26700959
|
Rondini EA et al. |
Transcriptional Regulation of Cytosolic Sulfotransferase 1C2 by Intermediates of the Cholesterol Biosynthetic Pathway in Primary Cultured Rat Hepatocytes. |
2015 |
J. Pharmacol. Exp. Ther. |
pmid:26427720
|
da Silva MF et al. |
In Vitro Antimalarial Activity of Different Inhibitors of the Plasmodial Isoprenoid Synthesis Pathway. |
2015 |
Antimicrob. Agents Chemother. |
pmid:26055383
|
Zúñiga-Hertz JP et al. |
Distinct pathways of cholesterol biosynthesis impact on insulin secretion. |
2015 |
J. Endocrinol. |
pmid:25453115
|
Bentinger M et al. |
Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis. |
2014 |
Biochim. Biophys. Acta |
pmid:24747199
|
Hamid PH et al. |
Differential inhibition of host cell cholesterol de novo biosynthesis and processing abrogates Eimeria bovis intracellular development. |
2014 |
Parasitol. Res. |
pmid:25199551
|
Quade-Lyssy P et al. |
Statins stimulate the production of a soluble form of the receptor for advanced glycation end products. |
2013 |
J. Lipid Res. |
pmid:23966666
|
Liu CI et al. |
Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase. |
2012 |
J. Biol. Chem. |
pmid:22474324
|
Cannell RJ et al. |
Follow-up of natural products isolation. |
2012 |
Methods Mol. Biol. |
pmid:22367909
|
Fünfschilling U et al. |
Critical time window of neuronal cholesterol synthesis during neurite outgrowth. |
2012 |
J. Neurosci. |
pmid:22649242
|
Stein W et al. |
Prevention of transplant coronary artery disease by prenylation inhibitors. |
2011 |
J. Heart Lung Transplant. |
pmid:21458297
|
Henneman L et al. |
Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS. |
2011 |
Biochim. Biophys. Acta |
pmid:21237288
|
Haeuptle MA et al. |
Improvement of dolichol-linked oligosaccharide biosynthesis by the squalene synthase inhibitor zaragozic acid. |
2011 |
J. Biol. Chem. |
pmid:21183681
|