Cannell RJ et al. |
Production of additional squalestatin analogues by directed biosynthesis. |
1994 |
J. Antibiot. |
pmid:8150722
|
Correll CC and Edwards PA |
Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro. |
1994 |
J. Biol. Chem. |
pmid:8276863
|
Dufresne C et al. |
Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase. |
1993 |
J. Nat. Prod. |
pmid:8289063
|
Biftu T et al. |
Selective protection and relative importance of the carboxylic acid groups of zaragozic acid A for squalene synthase inhibition. |
1994 |
J. Med. Chem. |
pmid:8308869
|
Bergstrom JD et al. |
Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8419946
|
Gibbs JB et al. |
Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo. |
1993 |
J. Biol. Chem. |
pmid:8463291
|
Hasumi K et al. |
Competitive inhibition of squalene synthetase by squalestatin 1. |
1993 |
J. Antibiot. |
pmid:8501015
|
Bergstrom JD et al. |
Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase. |
1995 |
Annu. Rev. Microbiol. |
pmid:8561474
|
Ness GC et al. |
Inhibitors of cholesterol biosynthesis increase hepatic low-density lipoprotein receptor protein degradation. |
1996 |
Arch. Biochem. Biophys. |
pmid:8561503
|
Chan C et al. |
The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors. |
1996 |
J. Med. Chem. |
pmid:8568810
|
Keller RK et al. |
Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver. |
1996 |
Arch. Biochem. Biophys. |
pmid:8645011
|
Procopiou PA et al. |
The squalestatins: inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C3-modified analogues. |
1996 |
J. Med. Chem. |
pmid:8691471
|
Stankewich MC et al. |
Alterations in cell cholesterol content modulate Ca(2+)-induced tight junction assembly by MDCK cells. |
1996 |
Lipids |
pmid:8869884
|
Keller RK |
Squalene synthase inhibition alters metabolism of nonsterols in rat liver. |
1996 |
Biochim. Biophys. Acta |
pmid:8908150
|
Peffley DM and Gayen AK |
Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level. |
1997 |
Arch. Biochem. Biophys. |
pmid:9016820
|
Pirillo A et al. |
Simvastatin modulates the heat shock response and cytotoxicity mediated by oxidized LDL in cultured human endothelial smooth muscle cells. |
1997 |
Biochem. Biophys. Res. Commun. |
pmid:9070296
|
Bostedor RG et al. |
Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol. |
1997 |
J. Biol. Chem. |
pmid:9083051
|
Onishi JC et al. |
Antimicrobial activity of viridiofungins. |
1997 |
J. Antibiot. |
pmid:9186560
|
Corsini A et al. |
[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells]. |
1997 |
C. R. Seances Soc. Biol. Fil. |
pmid:9255346
|
Vlahcevic ZR et al. |
Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. |
1997 |
Gastroenterology |
pmid:9394735
|