Zhou Q et al. |
TGFbeta mediated transition of corneal fibroblasts from a proinflammatory state to a profibrotic state through modulation of histone acetylation. |
2010 |
J. Cell. Physiol. |
pmid:20232294
|
Chen WP et al. |
Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis. |
2010 |
Mol. Biol. Rep. |
pmid:20237852
|
Yoshikawa M et al. |
Trichostatin a prevents TGF-beta1-induced apoptosis by inhibiting ERK activation in human renal tubular epithelial cells. |
2010 |
Eur. J. Pharmacol. |
pmid:20553909
|
Mousa SA et al. |
Stress resistant human embryonic stem cells as a potential source for the identification of novel cancer stem cell markers. |
2010 |
Cancer Lett. |
pmid:19733430
|
Russell SB et al. |
Epigenetically altered wound healing in keloid fibroblasts. |
2010 |
J. Invest. Dermatol. |
pmid:20555348
|
Repouskou A et al. |
The circadian expression of c-MYC is modulated by the histone deacetylase inhibitor trichostatin A in synchronized murine neuroblastoma cells. |
2010 |
Chronobiol. Int. |
pmid:20560708
|
Liu TY et al. |
EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis. |
2010 |
Mol. Cancer |
pmid:20144199
|
Nam HJ et al. |
Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation. |
2010 |
J. Biol. Chem. |
pmid:20696758
|
Awe S and Renkawitz-Pohl R |
Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster. |
2010 |
Syst Biol Reprod Med |
pmid:20170286
|
Jichan Nie SW et al. |
Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent. |
2010 |
Reprod Sci |
pmid:20697142
|
Akiba Y et al. |
Histone deacetylase inhibitors de-repress tyrosine hydroxylase expression in the olfactory bulb and rostral migratory stream. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20170631
|
Costa-Borges N et al. |
Comparison between the effects of valproic acid and trichostatin A on the in vitro development, blastocyst quality, and full-term development of mouse somatic cell nuclear transfer embryos. |
2010 |
Cell Reprogram |
pmid:20698782
|
Islam NM et al. |
Bicyclic peptides as potent inhibitors of histone deacetylases: optimization of alkyl loop length. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20045316
|
Benny Klimek ME et al. |
Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20036643
|
Peng CY et al. |
Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines. |
2010 |
Leuk. Lymphoma |
pmid:20038232
|
MacTavish H et al. |
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors. |
2010 |
PLoS ONE |
pmid:21283510
|
Lei L et al. |
Epigenetic repression of SATB1 by polycomb group protein EZH2 in epithelial cells. |
2010 |
Chin. Med. Sci. J. |
pmid:21232178
|
Wang G et al. |
The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice. |
2010 |
Regen Med |
pmid:20210581
|
Obier N et al. |
Inhibition of histone deacetylases by Trichostatin A leads to a HoxB4-independent increase of hematopoietic progenitor/stem cell frequencies as a result of selective survival. |
2010 |
Cytotherapy |
pmid:20210674
|
Krishnan M et al. |
HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability. |
2010 |
Oncogene |
pmid:19881542
|
Fernandez G and Zeichner SL |
Cell line-dependent variability in HIV activation employing DNMT inhibitors. |
2010 |
Virol. J. |
pmid:20942961
|
Ibanez de Caceres I et al. |
IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer. |
2010 |
Oncogene |
pmid:20023704
|
Kuribayashi T et al. |
Scriptaid, a novel histone deacetylase inhibitor, enhances the response of human tumor cells to radiation. |
2010 |
Int. J. Mol. Med. |
pmid:19956898
|
Pollack BP et al. |
Ultraviolet radiation-induced transcription is associated with gene-specific histone acetylation. |
2009 May-Jun |
Photochem. Photobiol. |
pmid:19076306
|
Chen Z et al. |
BCL11A represses HBG transcription in K562 cells. |
2009 Mar-Apr |
Blood Cells Mol. Dis. |
pmid:19153051
|
Wang L et al. |
Using histone deacetylase inhibitors to enhance Foxp3(+) regulatory T-cell function and induce allograft tolerance. |
2009 Mar-Apr |
Immunol. Cell Biol. |
pmid:19172156
|
Allritz C et al. |
Endothelin-1 reverses the histone deacetylase inhibitor-induced increase in glial glutamate transporter transcription without affecting histone acetylation levels. |
2009 Jul-Aug |
Neurochem. Int. |
pmid:19428803
|
GarcÃa-Villegas R et al. |
Identification and functional characterization of the promoter of the mouse sodium-activated sodium channel Na(x) gene (Scn7a). |
2009 |
J. Neurosci. Res. |
pmid:19326446
|
Seo J et al. |
Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19289100
|
Cecconi D et al. |
Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. |
2009 |
Proteomics |
pmid:19294695
|
Ikeda S et al. |
Enhancement of histone acetylation by trichostatin A during in vitro fertilization of bovine oocytes affects cell number of the inner cell mass of the resulting blastocysts. |
2009 |
Zygote |
pmid:19356267
|
Morita K et al. |
Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells. |
2009 |
J. Neurosci. Res. |
pmid:19360904
|
von Burstin J et al. |
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex. |
2009 |
Gastroenterology |
pmid:19362090
|
Yang X et al. |
CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells. |
2009 |
PLoS ONE |
pmid:19340297
|
Slattery EL et al. |
Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. |
2009 |
J. Assoc. Res. Otolaryngol. |
pmid:19340485
|
Vilar E et al. |
Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. |
2009 |
Clin. Cancer Res. |
pmid:19351759
|
Bennett KL et al. |
AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. |
2009 |
PLoS ONE |
pmid:19742317
|
Meng CF et al. |
[Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells]. |
2009 |
Zhonghua Wei Chang Wai Ke Za Zhi |
pmid:19742343
|
Dombrowsky H et al. |
Conserved responses to trichostatin A in rodent lungs exposed to endotoxin or stretch. |
2009 |
Pulm Pharmacol Ther |
pmid:19744573
|
Dandrea M et al. |
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. |
2009 |
Nucleic Acids Res. |
pmid:19745053
|
Lugrin J et al. |
Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation. |
2009 |
Biochim. Biophys. Acta |
pmid:19747950
|
Cervera RP et al. |
Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryos. |
2009 |
Theriogenology |
pmid:19765811
|
Diplas AI et al. |
Demonstration of all-or-none loss of imprinting in mRNA expression in single cells. |
2009 |
Nucleic Acids Res. |
pmid:19767614
|
Ma XX et al. |
Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. |
2009 |
Eur. J. Gynaecol. Oncol. |
pmid:19697617
|
Chen FQ et al. |
Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea. |
2009 |
J. Neurochem. |
pmid:19141081
|
Zhao W et al. |
Histone deacetylase inhibitor, trichostatin A, affects gene expression patterns during morphogenesis of chicken limb buds in vivo. |
2009 |
Cells Tissues Organs (Print) |
pmid:19147985
|
Giustiniani J et al. |
Tubulin acetylation favors Hsp90 recruitment to microtubules and stimulates the signaling function of the Hsp90 clients Akt/PKB and p53. |
2009 |
Cell. Signal. |
pmid:19136058
|
Chen Y et al. |
3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment. |
2009 |
Eur J Med Chem |
pmid:19136179
|
Cowell RM et al. |
Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19118529
|
Wiesen JL and Tomasi TB |
Dicer is regulated by cellular stresses and interferons. |
2009 |
Mol. Immunol. |
pmid:19118902
|
Azzi A et al. |
Schistosoma mansoni: developmental arrest of miracidia treated with histone deacetylase inhibitors. |
2009 |
Exp. Parasitol. |
pmid:19094990
|
Hambach L et al. |
Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. |
2009 |
Blood |
pmid:19096014
|
Mavis CK et al. |
Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors. |
2009 |
Prostate |
pmid:19444856
|
Samuni Y et al. |
The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation. |
2009 |
Free Radic. Biol. Med. |
pmid:19447172
|
Gavin DP et al. |
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. |
2009 |
J Psychiatry Neurosci |
pmid:19448855
|
Astrand C et al. |
Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter. |
2009 |
Exp. Cell Res. |
pmid:19463811
|
Riester D et al. |
Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19457659
|
Kim HN et al. |
Trichostatin A inhibits osteoclastogenesis and bone resorption by suppressing the induction of c-Fos by RANKL. |
2009 |
Eur. J. Pharmacol. |
pmid:19766111
|
Woodfield GW et al. |
Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. |
2009 |
Clin. Cancer Res. |
pmid:19458056
|
Chen IH et al. |
Cytotoxic triterpenoids from the stems of Microtropis japonica. |
2009 |
J. Nat. Prod. |
pmid:19534471
|
Casero RA and Woster PM |
Recent advances in the development of polyamine analogues as antitumor agents. |
2009 |
J. Med. Chem. |
pmid:19534534
|
Dubois F et al. |
Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni. |
2009 |
Mol. Biochem. Parasitol. |
pmid:19538992
|
Ma XL et al. |
[Construction of anti-sense cDNA library of human breast cancer cells during apoptosis induced by trichostatin A and preliminary screening of essential genes]. |
2009 |
Zhonghua Yi Xue Za Zhi |
pmid:19567099
|
Moon C et al. |
Use of epigenetic modification to induce FOXP3 expression in naïve T cells. |
2009 |
Transplant. Proc. |
pmid:19545742
|
Thiel A et al. |
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. |
2009 |
Clin. Cancer Res. |
pmid:19584167
|
Rahim R and Strobl JS |
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. |
2009 |
Anticancer Drugs |
pmid:19584707
|
Nadasi E et al. |
Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells. |
2009 |
Anticancer Res. |
pmid:19528494
|
Han DW et al. |
Epigenetic hierarchy governing Nestin expression. |
2009 |
Stem Cells |
pmid:19415779
|
Derks S et al. |
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21. |
2009 |
Carcinogenesis |
pmid:19329758
|
Liu X et al. |
The improvement of adenovirus vector production by increased expression of coxsackie adenovirus receptor. |
2009 |
Biotechnol. Lett. |
pmid:19330491
|
Hollosi P et al. |
Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. |
2009 |
Int. J. Cancer |
pmid:19330836
|
Chen J et al. |
E1A has no effect on LPS-induced IL-6 secretion in rat alveolar epithelial cells. |
2009 |
Respiration |
pmid:19299891
|
Shao GB et al. |
Effect of trychostatin A treatment on gene expression in cloned mouse embryos. |
2009 |
Theriogenology |
pmid:19246084
|
Cunneen TS et al. |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells. |
2009 |
Arch. Ophthalmol. |
pmid:19365017
|
Charrier C et al. |
Synthesis and modeling of new benzofuranone histone deacetylase inhibitors that stimulate tumor suppressor gene expression. |
2009 |
J. Med. Chem. |
pmid:19385600
|
Åuczak MW and JagodziÅ„ski PP |
Trichostatin A down-regulates CYP19 transcript and protein levels in MCF-7 breast cancer cells. |
2009 |
Biomed. Pharmacother. |
pmid:18602794
|
Ma X et al. |
Identification of LIV1, a putative zinc transporter gene responsible for HDACi-induced apoptosis, using a functional gene screen approach. |
2009 |
Mol. Cancer Ther. |
pmid:19887557
|
Puca R et al. |
HIPK2 modulates p53 activity towards pro-apoptotic transcription. |
2009 |
Mol. Cancer |
pmid:19828042
|
Röhrs S et al. |
Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. |
2009 |
Mol. Cancer |
pmid:19835597
|
Wang Y et al. |
HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. |
2009 |
Neurosci. Lett. |
pmid:19835929
|
Mastitskaya S and Denecke B |
Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro. |
2009 |
J Negat Results Biomed |
pmid:19903342
|
Kawamura T et al. |
Inhibitory effects of short-chain fatty acids on matrix metalloproteinase secretion from human colonic subepithelial myofibroblasts. |
2009 |
Dig. Dis. Sci. |
pmid:18629644
|
Auer D et al. |
Expression of coxsackie-adenovirus receptor is related to estrogen sensitivity in breast cancer. |
2009 |
Breast Cancer Res. Treat. |
pmid:18618240
|
Sakurai T et al. |
Induction of endogenous interferon tau gene transcription by CDX2 and high acetylation in bovine nontrophoblast cells. |
2009 |
Biol. Reprod. |
pmid:19211809
|
Chakravorty M et al. |
IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin. |
2009 |
Int. J. Biochem. Cell Biol. |
pmid:19166966
|
Sharma A et al. |
Trichostatin a inhibits corneal haze in vitro and in vivo. |
2009 |
Invest. Ophthalmol. Vis. Sci. |
pmid:19168895
|
Li X et al. |
Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. |
2009 |
Blood |
pmid:19864643
|
Zubia A et al. |
Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity. |
2009 |
Oncogene |
pmid:19169274
|
Meng Q et al. |
Live birth of somatic cell-cloned rabbits following trichostatin A treatment and cotransfer of parthenogenetic embryos. |
2009 |
Cloning Stem Cells |
pmid:19196041
|
Gray SG et al. |
Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications. |
2009 |
Eur. J. Cancer |
pmid:19818596
|
Zhang F et al. |
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. |
2009 |
Cancer Biol. Ther. |
pmid:19270532
|
Hara D et al. |
Persistent BDNF exon I-IX mRNA expression following the withdrawal of neuronal activity in neurons. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19818730
|
Tan HH and Porter AG |
p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. |
2009 |
Biochem. Biophys. Res. Commun. |
pmid:19275888
|
Li C et al. |
Induction of myelogenous leukemia cells with histone deacetylase inhibitors through down-regulating the Daxx protein expression. |
2009 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:19821084
|
Gavin DP et al. |
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. |
2009 |
J Psychiatr Res |
pmid:19187942
|
Liberatore RA et al. |
NF-kappaB activity is constitutively elevated in c-Abl null fibroblasts. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805123
|
Sasaki K et al. |
Real-time imaging of histone H4 hyperacetylation in living cells. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805290
|
Gibbs A et al. |
Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:19805354
|
Popova EY et al. |
Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. |
2009 |
Chromosome Res. |
pmid:19172406
|
Lee JH et al. |
Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. |
2009 |
Mol. Cancer Res. |
pmid:19808903
|