Lietz M et al. |
RE-1 silencing transcription factor (REST) regulates human synaptophysin gene transcription through an intronic sequence-specific DNA-binding site. |
2003 |
Eur. J. Biochem. |
pmid:12492469
|
Yamashita Y et al. |
Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells. |
2003 |
Int. J. Cancer |
pmid:12494463
|
Rahman MM et al. |
Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. |
2003 |
Blood |
pmid:12511413
|
Musikacharoen T et al. |
Histone acetylation and activation of cAMP-response element-binding protein regulate transcriptional activation of MKP-M in lipopolysaccharide-stimulated macrophages. |
2003 |
J. Biol. Chem. |
pmid:12511574
|
Parekh-Olmedo H et al. |
The effect of hydroxyurea and trichostatin a on targeted nucleotide exchange in yeast and Mammalian cells. |
2003 |
Ann. N. Y. Acad. Sci. |
pmid:14751821
|
Nambu Y et al. |
Transcription-coupled events associating with immunoglobulin switch region chromatin. |
2003 |
Science |
pmid:14684824
|
Haggarty SJ et al. |
Small molecule modulation of the human chromatid decatenation checkpoint. |
2003 |
Chem. Biol. |
pmid:14700634
|
Kim DK et al. |
Synthesis and biological evaluation of 3-(4-substituted-phenyl)-N-hydroxy-2-propenamides, a new class of histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:14667227
|
Huang H et al. |
Expression of P53, P21 in human lung adenocarcinoma A549 cell strains under hypoxia conditions and the effect of TSA on their expression. |
2003 |
J. Huazhong Univ. Sci. Technol. Med. Sci. |
pmid:15015635
|
Senawong T et al. |
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression. |
2003 |
J. Biol. Chem. |
pmid:12930829
|
Mulholland NM et al. |
Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation. |
2003 |
Oncogene |
pmid:12894222
|
Banwell CM et al. |
Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation. |
2003 |
Recent Results Cancer Res. |
pmid:12899515
|
Yan Y et al. |
Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. |
2003 |
Toxicol. Appl. Pharmacol. |
pmid:12902198
|
Augenlicht L et al. |
Repression of MUC2 gene expression by butyrate, a physiological regulator of intestinal cell maturation. |
2003 |
Oncogene |
pmid:12902981
|
Cho B et al. |
Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12849980
|
Massillon D et al. |
Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. |
2003 |
J. Biol. Chem. |
pmid:12915406
|
Hong CY et al. |
Expression of MIS in the testis is downregulated by tumor necrosis factor alpha through the negative regulation of SF-1 transactivation by NF-kappa B. |
2003 |
Mol. Cell. Biol. |
pmid:12917325
|
Le Masson I et al. |
Yaf9, a novel NuA4 histone acetyltransferase subunit, is required for the cellular response to spindle stress in yeast. |
2003 |
Mol. Cell. Biol. |
pmid:12917332
|
Zhong S et al. |
Phosphorylation at serine 28 and acetylation at lysine 9 of histone H3 induced by trichostatin A. |
2003 |
Oncogene |
pmid:12917630
|
Thomas RM et al. |
Regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of SJL/J mice: role of Ikaros, demethylation, and chromatin structural change in the transcriptional activation of mammary tumor virus superantigen. |
2003 |
J. Immunol. |
pmid:12496403
|
Xu Y et al. |
SHP-1 sensitizes MCF-7 cells to trichostatin A-induced apoptosis by modulating PI3K-dependent events. |
2003 |
Cell Death Differ. |
pmid:14502244
|
Donadelli M et al. |
Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells. |
2003 |
Mol. Carcinog. |
pmid:14502645
|
Tominaga K et al. |
MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. |
2003 |
J. Biol. Chem. |
pmid:14506250
|
Kawai H et al. |
Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha. |
2003 |
Int. J. Cancer |
pmid:14506733
|
Witt O et al. |
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. |
2003 |
Blood |
pmid:12393499
|
Yang L et al. |
An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B. |
2003 |
Biochem. J. |
pmid:12398767
|
Klisovic DD et al. |
Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines. |
2003 |
Invest. Ophthalmol. Vis. Sci. |
pmid:12766035
|
Génin P et al. |
Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A. |
2003 |
J. Virol. |
pmid:12768031
|
Bartoli A et al. |
Effect of trichostatin a and 5'-azacytidine on transgene reactivation in U937 transduced cells. |
2003 |
Pharmacol. Res. |
pmid:12770523
|
Koeller KM et al. |
Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation. |
2003 |
Chem. Biol. |
pmid:12770822
|
Agoulnik IU et al. |
Repressors of androgen and progesterone receptor action. |
2003 |
J. Biol. Chem. |
pmid:12771131
|
Huang Y et al. |
Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. |
2003 |
Int. J. Cancer |
pmid:12640681
|
Méndez-Pertuz M et al. |
The thyroid hormone receptor antagonizes CREB-mediated transcription. |
2003 |
EMBO J. |
pmid:12805224
|
Illi B et al. |
Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression. |
2003 |
Circ. Res. |
pmid:12805238
|
Bhakat KK and Mitra S |
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. |
2003 |
Carcinogenesis |
pmid:12807730
|
Lopatina NG et al. |
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:12810068
|
Liu LT et al. |
Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. |
2003 |
Cancer Res. |
pmid:12810630
|
Shin HJ et al. |
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation. |
2003 |
Oncogene |
pmid:12813458
|
Kim HS et al. |
Regulation of the tyrosine hydroxylase gene promoter by histone deacetylase inhibitors. |
2003 |
Biochem. Biophys. Res. Commun. |
pmid:14651963
|
Coombes MM et al. |
Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation. |
2003 |
Oncogene |
pmid:14654786
|
Chan AS et al. |
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. |
2003 |
Oncogene |
pmid:14534543
|
Allison SJ and Milner J |
Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. |
2003 |
Cancer Res. |
pmid:14583461
|
Mai A et al. |
Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A. |
2003 |
J. Med. Chem. |
pmid:14584932
|
Pace BS et al. |
p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors. |
2003 |
Exp. Hematol. |
pmid:14585374
|
Shteper PJ et al. |
Role of promoter methylation in regulation of the mammalian heparanase gene. |
2003 |
Oncogene |
pmid:14586400
|
Hirose T et al. |
p53-independent induction of Gadd45 by histone deacetylase inhibitor: coordinate regulation by transcription factors Oct-1 and NF-Y. |
2003 |
Oncogene |
pmid:14586402
|
Vanommeslaeghe K et al. |
Ab initio study of the binding of Trichostatin A (TSA) in the active site of histone deacetylase like protein (HDLP). |
2003 |
Org. Biomol. Chem. |
pmid:12968347
|
Huang H et al. |
[HDAC1 expression and effect of TSA on proliferation and apoptosis of A549 cells]. |
2003 |
Ai Zheng |
pmid:12969522
|
Ohike N et al. |
Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas. |
2003 |
Cancer Lett. |
pmid:12969792
|
Fass DM et al. |
Deacetylase activity is required for cAMP activation of a subset of CREB target genes. |
2003 |
J. Biol. Chem. |
pmid:12939274
|
Zhao C et al. |
A composite motif of the Drosophila morphogenetic protein bicoid critical to transcription control. |
2003 |
J. Biol. Chem. |
pmid:12939280
|
Hinoi T et al. |
Silencing of CDX2 expression in colon cancer via a dominant repression pathway. |
2003 |
J. Biol. Chem. |
pmid:12947088
|
Nakano M et al. |
Epigenetic assembly of centromeric chromatin at ectopic alpha-satellite sites on human chromosomes. |
2003 |
J. Cell. Sci. |
pmid:12953060
|
Kim EJ et al. |
Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML. |
2003 |
Nucleic Acids Res. |
pmid:12954772
|
Brugarolas JB et al. |
TSC2 regulates VEGF through mTOR-dependent and -independent pathways. |
2003 |
Cancer Cell |
pmid:12957289
|
Cimini D et al. |
Histone hyperacetylation in mitosis prevents sister chromatid separation and produces chromosome segregation defects. |
2003 |
Mol. Biol. Cell |
pmid:12972566
|
Schuettengruber B et al. |
Autoregulation of mouse histone deacetylase 1 expression. |
2003 |
Mol. Cell. Biol. |
pmid:12972616
|
Hoever G et al. |
The mechanism of 3'-azido-2',3'-dideoxythymidine resistance to human lymphoid cells. |
2003 |
Int. J. Mol. Med. |
pmid:12736716
|
Valenta T et al. |
HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. |
2003 |
Nucleic Acids Res. |
pmid:12711682
|
Arora T et al. |
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4. |
2003 |
J. Biol. Chem. |
pmid:12716907
|
Sonoyama K et al. |
Upregulation of activin A gene by butyrate in human colon cancer cell lines. |
2003 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:12540370
|
Kagoshima M et al. |
Glucocorticoid suppression of nuclear factor-kappa B: a role for histone modifications. |
2003 |
Biochem. Soc. Trans. |
pmid:12546654
|
Bhat RA et al. |
Alteration of GCN5 levels in maize reveals dynamic responses to manipulating histone acetylation. |
2003 |
Plant J. |
pmid:12581304
|
Jang IC et al. |
Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture. |
2003 |
Plant J. |
pmid:12581311
|
Bouchain G et al. |
Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors. |
2003 |
J. Med. Chem. |
pmid:12593661
|
Castro-Galache MD et al. |
Susceptibility of multidrug resistance tumor cells to apoptosis induction by histone deacetylase inhibitors. |
2003 |
Int. J. Cancer |
pmid:12594812
|
Teyssier C et al. |
Receptor-interacting protein 140 binds c-Jun and inhibits estradiol-induced activator protein-1 activity by reversing glucocorticoid receptor-interacting protein 1 effect. |
2003 |
Mol. Endocrinol. |
pmid:12554755
|
Noss KR et al. |
Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines. |
2002 May-Jun |
Anticancer Res. |
pmid:12168830
|
Rahman I et al. |
Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. |
2002 May-Jun |
Mol. Cell. Biochem. |
pmid:12162440
|
Iwata K et al. |
Trichostatin A, a histone deacetylase inhibitor, down-regulates interleukin-12 transcription in SV-40-transformed lung epithelial cells. |
2002 Jul-Aug |
Cell. Immunol. |
pmid:12470611
|
Sourlingas TG et al. |
The effect of the histone deacetylase inhibitor, trichostatin A, on total histone synthesis, H1(0) synthesis and histone H4 acetylation in peripheral blood lymphocytes increases as a function of increasing age: a model study. |
2002 Jan-Mar |
Exp. Gerontol. |
pmid:11772521
|
López-Solache I et al. |
Regulation of uncoupling protein-2 mRNA in L6 myotubules: II: Thyroid hormone amplifies stimulation of uncoupling protein-2 gene by thiazolidinediones and other peroxisome proliferator-activated receptor ligands in L6 myotubules: evidence for a priming effect. |
2002 |
Endocrine |
pmid:12588052
|
Strait KA et al. |
Cell cycle blockade and differentiation of ovarian cancer cells by the histone deacetylase inhibitor trichostatin A are associated with changes in p21, Rb, and Id proteins. |
2002 |
Mol. Cancer Ther. |
pmid:12479699
|
Blagosklonny MV et al. |
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity. |
2002 |
Mol. Cancer Ther. |
pmid:12481415
|
Kim JY et al. |
Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation. |
2002 |
Anal. Chem. |
pmid:12433071
|
Elaut G et al. |
Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes. |
2002 |
Drug Metab. Dispos. |
pmid:12433798
|
Yáñez RJ and Porter AC |
A chromosomal position effect on gene targeting in human cells. |
2002 |
Nucleic Acids Res. |
pmid:12433992
|
Takechi S et al. |
Chicken HDAC2 down-regulates IgM light chain gene promoter activity. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12437980
|
Heltweg B and Jung M |
A microplate reader-based nonisotopic histone deacetylase activity assay. |
2002 |
Anal. Biochem. |
pmid:11878795
|
Kamitani H et al. |
Histone acetylation may suppress human glioma cell proliferation when p21 WAF/Cip1 and gelsolin are induced. |
2002 |
Neuro-oncology |
pmid:11916500
|
Ginjala V et al. |
Multiple cis elements within the Igf2/H19 insulator domain organize a distance-dependent silencer. A cautionary note. |
2002 |
J. Biol. Chem. |
pmid:11777900
|
Cabral AL et al. |
Regulation of the cellular prion protein gene expression depends on chromatin conformation. |
2002 |
J. Biol. Chem. |
pmid:11739375
|
Park SH et al. |
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. |
2002 |
J. Biol. Chem. |
pmid:11744689
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Li J et al. |
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. |
2002 |
Mol. Cell. Biol. |
pmid:12138181
|
Aapola U et al. |
Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity. |
2002 |
Nucleic Acids Res. |
pmid:12177302
|
Chang TH and Szabo E |
Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. |
2002 |
Clin. Cancer Res. |
pmid:11948134
|
Ventura A et al. |
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. |
2002 |
J. Biol. Chem. |
pmid:11948181
|
Gradoville L et al. |
Protein kinase C-independent activation of the Epstein-Barr virus lytic cycle. |
2002 |
J. Virol. |
pmid:11991990
|
Uesato S et al. |
Novel histone deacetylase inhibitors: N-hydroxycarboxamides possessing a terminal bicyclic aryl group. |
2002 |
Bioorg. Med. Chem. Lett. |
pmid:11992774
|
Nambiar MP et al. |
Effect of trichostatin A on human T cells resembles signaling abnormalities in T cells of patients with systemic lupus erythematosus: a new mechanism for TCR zeta chain deficiency and abnormal signaling. |
2002 |
J. Cell. Biochem. |
pmid:11967985
|
Wang XQ et al. |
Histone deacetylase inhibition results in decreased macrophage CD9 expression. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12056820
|
Rahmani M et al. |
The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process. |
2002 |
Exp. Cell Res. |
pmid:12061815
|
Woo SH et al. |
Structurally simple trichostatin A-like straight chain hydroxamates as potent histone deacetylase inhibitors. |
2002 |
J. Med. Chem. |
pmid:12061890
|
Chen Y et al. |
On the epigenetic regulation of the human reelin promoter. |
2002 |
Nucleic Acids Res. |
pmid:12087179
|
Zhang Y and Dufau ML |
Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex. |
2002 |
J. Biol. Chem. |
pmid:12091390
|
Danbara M et al. |
DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines. |
2002 |
Mol. Immunol. |
pmid:12044782
|
Lin HM et al. |
Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors. |
2002 |
J. Biol. Chem. |
pmid:12048199
|
Quivy V et al. |
Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies. |
2002 |
J. Virol. |
pmid:12368351
|
Smith WL and Edlind TD |
Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. |
2002 |
Antimicrob. Agents Chemother. |
pmid:12384361
|