Kurtev V et al. |
Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases. |
2004 |
J. Biol. Chem. |
pmid:15140878
|
Kim YH et al. |
Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells. |
2004 |
Carcinogenesis |
pmid:15142888
|
Kato N et al. |
Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines. |
2004 |
Cell Death Differ. |
pmid:15153943
|
Zoumpoulidou G et al. |
Convergence of interferon-gamma and progesterone signaling pathways in human endometrium: role of PIASy (protein inhibitor of activated signal transducer and activator of transcription-y). |
2004 |
Mol. Endocrinol. |
pmid:15155784
|
Wang LG et al. |
Androgen receptor level controlled by a suppressor complex lost in an androgen-independent prostate cancer cell line. |
2004 |
Oncogene |
pmid:15156193
|
Zhang Y et al. |
Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors. |
2004 |
Radiat. Res. |
pmid:15161353
|
Glenn MP et al. |
Antiproliferative and phenotype-transforming antitumor agents derived from cysteine. |
2004 |
J. Med. Chem. |
pmid:15163181
|
Ronai D et al. |
The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature. |
2004 |
Genetics |
pmid:15166165
|
Zhang X et al. |
Activation of the growth-differentiation factor 11 gene by the histone deacetylase (HDAC) inhibitor trichostatin A and repression by HDAC3. |
2004 |
Mol. Cell. Biol. |
pmid:15169878
|
Lee YJ et al. |
Mechanism of transcriptional repression by TEL/RUNX1 fusion protein. |
2004 |
Mol. Cells |
pmid:15179033
|
Flørenes VA et al. |
Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival. |
2004 |
Melanoma Res. |
pmid:15179185
|
Ahn MR et al. |
Trichostatin A, a histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in Hepa-I cells. |
2004 |
Arch. Pharm. Res. |
pmid:15180307
|
Vanhaecke T et al. |
Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view. |
2004 |
Curr. Med. Chem. |
pmid:15180568
|
Ishiguro K and Sartorelli AC |
Activation of transiently transfected reporter genes in 3T3 Swiss cells by the inducers of differentiation/apoptosis--dimethylsulfoxide, hexamethylene bisacetamide and trichostatin A. |
2004 |
Eur. J. Biochem. |
pmid:15182353
|
Brieger A et al. |
In bcr-abl-positive myeloid cells resistant to conventional chemotherapeutic agents, expression of Par-4 increases sensitivity to imatinib (STI571) and histone deacetylase-inhibitors. |
2004 |
Biochem. Pharmacol. |
pmid:15183120
|
Sakamoto S et al. |
Histone deacetylase activity is required to recruit RNA polymerase II to the promoters of selected interferon-stimulated early response genes. |
2004 |
J. Biol. Chem. |
pmid:15194680
|
Ng Y et al. |
Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding. |
2004 |
J. Biol. Chem. |
pmid:15194684
|
Lu H et al. |
Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat. |
2004 |
J. Virol. |
pmid:15194748
|
Moldenhauer A et al. |
Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins. |
2004 |
J. Leukoc. Biol. |
pmid:15197237
|
Min KN et al. |
Estrogen receptor enhances the antiproliferative effects of trichostatin A and HC-toxin in human breast cancer cells. |
2004 |
Arch. Pharm. Res. |
pmid:15202563
|
Korzus E et al. |
CBP histone acetyltransferase activity is a critical component of memory consolidation. |
2004 |
Neuron |
pmid:15207240
|
Ishihara K et al. |
Possible mechanism of action of the histone deacetylase inhibitors for the induction of differentiation of HL-60 clone 15 cells into eosinophils. |
2004 |
Br. J. Pharmacol. |
pmid:15210580
|
Jia S et al. |
RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins. |
2004 |
Science |
pmid:15218150
|
Sumer H et al. |
Effects of scaffold/matrix alteration on centromeric function and gene expression. |
2004 |
J. Biol. Chem. |
pmid:15220334
|
Fang JY et al. |
Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116. |
2004 |
Cell Res. |
pmid:15225415
|
Banwell CM et al. |
Targeting 1alpha,25-dihydroxyvitamin D3 antiproliferative insensitivity in breast cancer cells by co-treatment with histone deacetylation inhibitors. |
2004 |
J. Steroid Biochem. Mol. Biol. |
pmid:15225779
|
Mao DY et al. |
Promoter-binding and repression of PDGFRB by c-Myc are separable activities. |
2004 |
Nucleic Acids Res. |
pmid:15226411
|
Naruse Y et al. |
Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation. |
2004 |
Mol. Cell. Biol. |
pmid:15226430
|
Chen WK et al. |
[Effect of trichostatin A on histone acetylation level and apoptosis in HL-60 cells]. |
2004 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
pmid:15228659
|
Kim JH et al. |
Susceptibility and radiosensitization of human glioblastoma cells to trichostatin A, a histone deacetylase inhibitor. |
2004 |
Int. J. Radiat. Oncol. Biol. Phys. |
pmid:15234053
|
De La Fuente R et al. |
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. |
2004 |
Dev. Biol. |
pmid:15242786
|
Kang J et al. |
Synergistic killing of human leukemia cells by antioxidants and trichostatin A. |
2004 |
Cancer Chemother. Pharmacol. |
pmid:15248029
|
Jin B and Ryu DY |
Regulation of CYP1A2 by histone deacetylase inhibitors in mouse hepatocytes. |
2004 |
J. Biochem. Mol. Toxicol. |
pmid:15252868
|
Gilchrist S et al. |
Nuclear organization of centromeric domains is not perturbed by inhibition of histone deacetylases. |
2004 |
Chromosome Res. |
pmid:15254368
|
Aggarwal BD and Calvi BR |
Chromatin regulates origin activity in Drosophila follicle cells. |
2004 |
Nature |
pmid:15254542
|
Marengo E et al. |
Identification of the regulatory proteins in human pancreatic cancers treated with Trichostatin A by 2D-PAGE maps and multivariate statistical analysis. |
2004 |
Anal Bioanal Chem |
pmid:15257427
|
Schauber J et al. |
Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells. |
2004 |
Mol. Immunol. |
pmid:15261456
|
Sanderson L et al. |
Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice. |
2004 |
Drug Metab. Dispos. |
pmid:15269190
|
Levenson JM et al. |
Regulation of histone acetylation during memory formation in the hippocampus. |
2004 |
J. Biol. Chem. |
pmid:15273246
|
Liu C and Xu D |
Inhibition of histone deacetylases. |
2004 |
Methods Mol. Biol. |
pmid:15273406
|
Garfinkel MD et al. |
Multigenerational selection and detection of altered histone acetylation and methylation patterns: toward a quantitative epigenetics in Drosophila. |
2004 |
Methods Mol. Biol. |
pmid:15273410
|
Vanhaecke T et al. |
Effect of the histone deacetylase inhibitor trichostatin A on spontaneous apoptosis in various types of adult rat hepatocyte cultures. |
2004 |
Biochem. Pharmacol. |
pmid:15276083
|
Akimoto T |
[Potentiation of radiation-induced cell killing by histone deacetylase inhibitor]. |
2004 |
Nippon Rinsho |
pmid:15283155
|
Joung KE et al. |
Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells. |
2004 |
Arch. Pharm. Res. |
pmid:15283467
|
Iijima K et al. |
Granulocytic differentiation of leukemic cells with t(9;11)(p22;q23) induced by all-trans-retinoic acid. |
2004 |
Leuk. Lymphoma |
pmid:15291362
|
Fenic I et al. |
In vivo effects of histone-deacetylase inhibitor trichostatin-A on murine spermatogenesis. |
2004 Sep-Oct |
J. Androl. |
pmid:15292114
|
Tóth KF et al. |
Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin. |
2004 |
J. Cell. Sci. |
pmid:15292402
|
Fishel ML et al. |
Effect of cell cycle inhibition on Cisplatin-induced cytotoxicity. |
2005 |
J. Pharmacol. Exp. Ther. |
pmid:15304523
|
Yanaihara N et al. |
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer. |
2004 |
Int. J. Cancer |
pmid:15305387
|
Gaudier E et al. |
Butyrate specifically modulates MUC gene expression in intestinal epithelial goblet cells deprived of glucose. |
2004 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
pmid:15308471
|
Chen YX et al. |
Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines. |
2004 |
World J. Gastroenterol. |
pmid:15309711
|
Myzak MC et al. |
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. |
2004 |
Cancer Res. |
pmid:15313918
|
Facchetti F et al. |
Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors. |
2004 |
Apoptosis |
pmid:15314285
|
Roh MS et al. |
Mechanism of histone deacetylase inhibitor Trichostatin A induced apoptosis in human osteosarcoma cells. |
2004 |
Apoptosis |
pmid:15314286
|
Schultz BE et al. |
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. |
2004 |
Biochemistry |
pmid:15323567
|
Chiba T et al. |
Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells. |
2004 |
J. Hepatol. |
pmid:15336447
|
Liu CJ et al. |
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. |
2004 |
J. Biol. Chem. |
pmid:15337766
|
Cosio BG et al. |
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. |
2004 |
J. Exp. Med. |
pmid:15337792
|
Tao D et al. |
Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression. |
2004 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:15346199
|
Korkmaz CG et al. |
Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants. |
2004 |
J. Endocrinol. |
pmid:15350180
|
Tang XX et al. |
Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. |
2004 |
Clin. Cancer Res. |
pmid:15355914
|
Yokota T et al. |
Trichostatin A activates p18INK4c gene: differential activation and cooperation with p19INK4d gene. |
2004 |
FEBS Lett. |
pmid:15358560
|
Boehrer S et al. |
In the erythroleukemic cell line HEL Prostate-apoptosis-response-gene-4 (par-4) fails to down-regulate Bcl-2 and to promote apoptosis. |
2004 |
Leuk. Lymphoma |
pmid:15359646
|
Vaghefi H and Neet KE |
Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation. |
2004 |
Oncogene |
pmid:15361854
|
Moore PS et al. |
Gene expression profiling after treatment with the histone deacetylase inhibitor trichostatin A reveals altered expression of both pro- and anti-apoptotic genes in pancreatic adenocarcinoma cells. |
2004 |
Biochim. Biophys. Acta |
pmid:15363630
|
Laeng P et al. |
The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells. |
2004 |
J. Neurochem. |
pmid:15379904
|
Kim MK and Carroll WL |
Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2. |
2004 |
Cancer |
pmid:15382088
|
Davis FJ et al. |
Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility. |
2005 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:15388503
|
Chen JS and Faller DV |
Histone deacetylase inhibition-mediated post-translational elevation of p27KIP1 protein levels is required for G1 arrest in fibroblasts. |
2005 |
J. Cell. Physiol. |
pmid:15389542
|
Frønsdal K and Saatcioglu F |
Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. |
2005 |
Prostate |
pmid:15389787
|
Fan X et al. |
Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells. |
2004 |
J. Cell. Biochem. |
pmid:15389882
|
Zelko IN and Folz RJ |
Sp1 and Sp3 transcription factors mediate trichostatin A-induced and basal expression of extracellular superoxide dismutase. |
2004 |
Free Radic. Biol. Med. |
pmid:15451065
|
Chiba T et al. |
Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells. |
2004 |
Oncology |
pmid:15452378
|
Jose B et al. |
Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones. |
2004 |
Bioorg. Med. Chem. Lett. |
pmid:15454224
|
Uramoto H et al. |
p73 competes with co-activators and recruits histone deacetylase to NF-Y in the repression of PDGF beta-receptor. |
2004 |
J. Cell. Sci. |
pmid:15454570
|
Heltweg B et al. |
Subtype selective substrates for histone deacetylases. |
2004 |
J. Med. Chem. |
pmid:15456267
|
Sarg B et al. |
Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation. |
2004 |
J. Biol. Chem. |
pmid:15456746
|
Jori FP et al. |
RB and RB2/p130 genes demonstrate both specific and overlapping functions during the early steps of in vitro neural differentiation of marrow stromal stem cells. |
2005 |
Cell Death Differ. |
pmid:15459751
|
Nan X et al. |
Potent stimulation of gene expression by histone deacetylase inhibitors on transiently transfected DNA. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15465025
|
Lee HS et al. |
Gene expression analysis in human gastric cancer cell line treated with trichostatin A and S-adenosyl-L-homocysteine using cDNA microarray. |
2004 |
Biol. Pharm. Bull. |
pmid:15467184
|
Sangster-Guity N et al. |
Molecular profiling of embryonal carcinoma cells following retinoic acid or histone deacetylase inhibitor treatment. |
2004 |
Cancer Biol. Ther. |
pmid:15467438
|
Vaquero A et al. |
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. |
2004 |
Mol. Cell |
pmid:15469825
|
Ladd PD et al. |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus. |
2004 |
Gene |
pmid:15474314
|
Li H and Wu X |
Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. |
2004 |
Biochem. Biophys. Res. Commun. |
pmid:15474507
|
Spenger A et al. |
Influence of promoter choice and trichostatin A treatment on expression of baculovirus delivered genes in mammalian cells. |
2004 |
Protein Expr. Purif. |
pmid:15477077
|
Alcendor RR et al. |
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. |
2004 |
Circ. Res. |
pmid:15486319
|
Gius D et al. |
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. |
2004 |
Cancer Cell |
pmid:15488759
|
Alikhani-Koopaei R et al. |
Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression. |
2004 |
J. Clin. Invest. |
pmid:15489962
|
Yee SB et al. |
Trichostatin A induces apoptosis of p815 mastocytoma cells in histone acetylation- and mitochondria-dependent fashion. |
2004 |
Int. J. Oncol. |
pmid:15492835
|
Emmans VC et al. |
Regulation of cellular processes by PPARgamma ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. |
2004 |
Biochem. Soc. Trans. |
pmid:15494029
|
Spengler ML et al. |
Sumoylation of internally initiated Sp3 isoforms regulates transcriptional repression via a Trichostatin A-insensitive mechanism. |
2005 |
Cell. Signal. |
pmid:15494207
|
Canes D et al. |
Histone deacetylase inhibitors upregulate plakoglobin expression in bladder carcinoma cells and display antineoplastic activity in vitro and in vivo. |
2005 |
Int. J. Cancer |
pmid:15499627
|
De La Fuente R et al. |
Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function. |
2004 |
Dev. Biol. |
pmid:15501230
|
Lin AC et al. |
The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors. |
2004 |
J. Biol. Chem. |
pmid:15507435
|
Chang S and Pikaard CS |
Transcript profiling in Arabidopsis reveals complex responses to global inhibition of DNA methylation and histone deacetylation. |
2005 |
J. Biol. Chem. |
pmid:15516340
|
Wang S and Zhu J |
The hTERT gene is embedded in a nuclease-resistant chromatin domain. |
2004 |
J. Biol. Chem. |
pmid:15516693
|
El-Khoury V et al. |
Effects of the histone deacetylase inhibitor trichostatin A on nuclear texture and c-jun gene expression in drug-sensitive and drug-resistant human H69 lung carcinoma cells. |
2004 |
Cytometry A |
pmid:15517561
|
Kawano T et al. |
Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect. |
2004 Sep-Oct |
Anticancer Res. |
pmid:15517875
|
Hammond SM et al. |
Negative regulatory elements are present in the human LMO2 oncogene and may contribute to its expression in leukemia. |
2005 |
Leuk. Res. |
pmid:15541480
|
Ramakrishnan G et al. |
Histone acetyltransferases and deacetylase in Entamoeba histolytica. |
2004 |
Mol. Biochem. Parasitol. |
pmid:15555732
|