trichostatin A

Trichostatin is a lipid of Polyketides (PK) class. Trichostatin is associated with abnormalities such as Dentatorubral-Pallidoluysian Atrophy, PARAGANGLIOMAS 3, abnormal fragmented structure, Disintegration (morphologic abnormality) and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Acetylation, Cell Differentiation process, histone modification, Gene Silencing and Transcriptional Activation. Trichostatin often locates in CD41a, Hematopoietic System, Chromatin Structure, Blood and Endothelium. The associated genes with Trichostatin are SPI1 gene, CELL Gene, Chromatin, CXCR4 gene and DNMT1 gene. The related lipids are Butyrates, Promega, butyrate, Lipopolysaccharides and Steroids. The related experimental models are Knock-out, Mouse Model, Xenograft Model and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of trichostatin A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with trichostatin A?

trichostatin A is suspected in Infection, Morphologically altered structure, Ureteral obstruction, Photosensitization, Atherosclerosis, Hypertrophic Cardiomyopathy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with trichostatin A

MeSH term MeSH ID Detail
Thyroid Hormone Resistance Syndrome D018382 1 associated lipids
Chromosome Inversion D007446 1 associated lipids
Rhabdomyosarcoma, Embryonal D018233 1 associated lipids
Carcinoma, Papillary, Follicular D018265 1 associated lipids
Gestational Trophoblastic Disease D031901 1 associated lipids
Rhabdoid Tumor D018335 1 associated lipids
Visceral Pain D059265 1 associated lipids
Lupus Vulgaris D008177 1 associated lipids
Rubinstein-Taybi Syndrome D012415 1 associated lipids
Classical Lissencephalies and Subcortical Band Heterotopias D054221 1 associated lipids
Goldenhar Syndrome D006053 1 associated lipids
Adenomyosis D062788 1 associated lipids
Capsule Opacification D058442 1 associated lipids
Neoplasm Micrometastasis D061206 1 associated lipids
Cystadenoma, Serous D018293 1 associated lipids
Supratentorial Neoplasms D015173 1 associated lipids
von Hippel-Lindau Disease D006623 1 associated lipids
Intervertebral Disc Degeneration D055959 1 associated lipids
Hypesthesia D006987 1 associated lipids
Cystadenocarcinoma, Mucinous D018282 1 associated lipids
Myopathy, Central Core D020512 1 associated lipids
Roseolovirus Infections D019349 1 associated lipids
Cystadenocarcinoma, Serous D018284 2 associated lipids
Fibromatosis, Aggressive D018222 2 associated lipids
Rhabdomyosarcoma, Alveolar D018232 2 associated lipids
Small Cell Lung Carcinoma D055752 2 associated lipids
Bone Marrow Neoplasms D019046 2 associated lipids
Adenocarcinoma, Papillary D000231 2 associated lipids
Inflammatory Breast Neoplasms D058922 2 associated lipids
Ganglioneuroma D005729 2 associated lipids
Mastocytoma D034801 3 associated lipids
Uveal Neoplasms D014604 3 associated lipids
Leukemia, Promyelocytic, Acute D015473 3 associated lipids
Conjunctival Neoplasms D003230 3 associated lipids
Adenocarcinoma, Follicular D018263 3 associated lipids
Hypereosinophilic Syndrome D017681 3 associated lipids
Lymphoma, Follicular D008224 3 associated lipids
Lymphoma, Large-Cell, Anaplastic D017728 3 associated lipids
Retinal Neoplasms D019572 3 associated lipids
Progeria D011371 3 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Nasopharyngeal Neoplasms D009303 4 associated lipids
Neuroendocrine Tumors D018358 4 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Opioid-Related Disorders D009293 5 associated lipids
Osteomalacia D010018 5 associated lipids
Fragile X Syndrome D005600 5 associated lipids
Myeloproliferative Disorders D009196 5 associated lipids
Leukemia, Myelomonocytic, Acute D015479 6 associated lipids
Polycystic Kidney, Autosomal Dominant D016891 6 associated lipids
Carcinoma, Pancreatic Ductal D021441 6 associated lipids
Primary Myelofibrosis D055728 6 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Genomic Instability D042822 7 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Immunologic Deficiency Syndromes D007153 8 associated lipids
Enteritis D004751 8 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Fetal Growth Retardation D005317 9 associated lipids
Chondrosarcoma D002813 9 associated lipids
Mast-Cell Sarcoma D012515 9 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Carcinoma, Renal Cell D002292 12 associated lipids
Retinoblastoma D012175 12 associated lipids
Keloid D007627 12 associated lipids
Cat Diseases D002371 12 associated lipids
Sciatic Neuropathy D020426 13 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Neoplasms D009369 13 associated lipids
Intellectual Disability D008607 13 associated lipids
Radiation Injuries D011832 14 associated lipids
Brain Neoplasms D001932 15 associated lipids
Tongue Neoplasms D014062 15 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Carcinoma D002277 18 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Leishmaniasis D007896 19 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Translocation, Genetic D014178 20 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Hypersensitivity D006967 22 associated lipids
Medulloblastoma D008527 22 associated lipids
Leukemia, T-Cell D015458 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Fibrosis D005355 23 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Breast Neoplasms D001943 24 associated lipids
Leukemia-Lymphoma, Adult T-Cell D015459 25 associated lipids
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Cell Transformation, Viral D002472 26 associated lipids
Nasal Polyps D009298 26 associated lipids
Glioblastoma D005909 27 associated lipids
Autoimmune Diseases D001327 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with trichostatin A

Lipid pathways are not clear in current pathway databases. We organized associated pathways with trichostatin A through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with trichostatin A?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with trichostatin A?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with trichostatin A?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with trichostatin A?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with trichostatin A?

Mouse Model

Mouse Model are used in the study 'Regulation of minichromosome maintenance gene family by microRNA-1296 and genistein in prostate cancer.' (Majid S et al., 2010), Mouse Model are used in the study 'Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.' (Fang MZ et al., 2005) and Mouse Model are used in the study 'Histone deacetylase 3 mediates allergic skin inflammation by regulating expression of MCP1 protein.' (Kim Y et al., 2012).

Xenograft Model

Xenograft Model are used in the study 'Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.' (Landreville S et al., 2012), Xenograft Model are used in the study 'Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.' (Moiseeva EP et al., 2007) and Xenograft Model are used in the study 'Retinoic acid and the histone deacetylase inhibitor trichostatin a inhibit the proliferation of human renal cell carcinoma in a xenograft tumor model.' (Touma SE et al., 2005).

Cancer Model

Cancer Model are used in the study 'Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice.' (Sanderson L et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with trichostatin A

Download all related citations
Per page 10 20 50 100 | Total 3126
Authors Title Published Journal PubMed Link
Tuncel M et al. The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake. 2007 Cancer Biother. Radiopharm. pmid:17600477
Kaneko M et al. Mechanism for the differentiation of EoL-1 cells into eosinophils by histone deacetylase inhibitors. 2007 Int. Arch. Allergy Immunol. pmid:17541273
Schwechter BR et al. Histone deacetylase inhibition-mediated differentiation of RGC-5 cells and interaction with survival. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17525221
Turaga RV et al. Werner syndrome protein prevents DNA breaks upon chromatin structure alteration. 2007 Aging Cell pmid:17521388
Wu J et al. Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing. 2007 BMC Genomics pmid:17524140
Wang LG et al. Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer. 2007 Mol. Carcinog. pmid:16921492
Choy SW et al. C. elegans SIN-3 and its associated HDAC corepressor complex act as mediators of male sensory ray development. 2007 Biochem. Biophys. Res. Commun. pmid:17506990
Uchida H et al. Histone deacetylase inhibitors stimulate cell migration in human endometrial adenocarcinoma cells through up-regulation of glycodelin. 2007 Endocrinology pmid:17068141
Roy S and Tenniswood M Site-specific acetylation of p53 directs selective transcription complex assembly. 2007 J. Biol. Chem. pmid:17121856
Zhang C et al. Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. 2007 J. Pathol. pmid:17471463
Gensert JM et al. CD81, a cell cycle regulator, is a novel target for histone deacetylase inhibition in glioma cells. 2007 Neurobiol. Dis. pmid:17481908
Mayo C et al. In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression. 2007 J. Cell. Physiol. pmid:17311291
Avila AM et al. Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy. 2007 J. Clin. Invest. pmid:17318264
Snykers S et al. Chromatin remodeling agent trichostatin A: a key-factor in the hepatic differentiation of human mesenchymal stem cells derived of adult bone marrow. 2007 BMC Dev. Biol. pmid:17407549
Horion J et al. Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha. 2007 J. Biol. Chem. pmid:17409387
Glenisson W et al. Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation. 2007 Biochim. Biophys. Acta pmid:17610967
Zhang X et al. Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression. 2007 Biochem. Cell Biol. pmid:17612628
Shi J et al. Effects of chromatin-modifying agents on CD34+ cells from patients with idiopathic myelofibrosis. 2007 Cancer Res. pmid:17616702
Perales M and Más P A functional link between rhythmic changes in chromatin structure and the Arabidopsis biological clock. 2007 Plant Cell pmid:17616736
Zhao Y et al. Roles of histone acetylation modification in basal and inducible expression of hsp26 gene in D. melanogaster. 2007 Mol. Cell. Biochem. pmid:17619947
El-Khoury V et al. The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model. 2007 Br. J. Cancer pmid:17667922
Khaw AK et al. Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells. 2007 Mutat. Res. pmid:17669439
Rouhi A et al. Plasticity of Ly49g expression is due to epigenetics. 2007 Mol. Immunol. pmid:16750269
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Shimazu T et al. [Biological diversity of protein lysine acetylation which has been revealed by small molecule inhibitors]. 2007 Tanpakushitsu Kakusan Koso pmid:18051411
Platta CS et al. The HDAC inhibitor trichostatin A inhibits growth of small cell lung cancer cells. 2007 J. Surg. Res. pmid:17612559
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Meng CF et al. Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines. 2007 World J. Gastroenterol. pmid:18069755
Rao J et al. Trichostatin-A induces differential changes in histone protein dynamics and expression in HeLa cells. 2007 Biochem. Biophys. Res. Commun. pmid:17869223
Ohoka N et al. Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion. 2007 J. Biol. Chem. pmid:17872950
Kenneth NS et al. TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17848523
Ferreira R et al. Site-specific acetylation of ISWI by GCN5. 2007 BMC Mol. Biol. pmid:17760996
Ting CH et al. Stat5 constitutive activation rescues defects in spinal muscular atrophy. 2007 Hum. Mol. Genet. pmid:17220171
McCool KW et al. The role of histone acetylation in regulating early gene expression patterns during early embryonic stem cell differentiation. 2007 J. Biol. Chem. pmid:17204470
Bártová E et al. Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites. 2007 Histochem. Cell Biol. pmid:17205308
Lattal KM et al. Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction. 2007 Behav. Neurosci. pmid:17907845
Zhang Y et al. An epigenetic modifier results in improved in vitro blastocyst production after somatic cell nuclear transfer. 2007 Cloning Stem Cells pmid:17907946
Noro R et al. PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors. 2007 Int. J. Oncol. pmid:17912443
Zhao TC et al. Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury. 2007 Cardiovasc. Res. pmid:17884027
Liu T et al. Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. 2007 Carcinogenesis pmid:16990345
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Jung J and Bonini N CREB-binding protein modulates repeat instability in a Drosophila model for polyQ disease. 2007 Science pmid:17332375
Jaffe RC et al. Histone deacetylase inhibition and progesterone act synergistically to stimulate baboon glycodelin gene expression. 2007 J. Mol. Endocrinol. pmid:17339403
Alimirah F et al. IFI16 in human prostate cancer. 2007 Mol. Cancer Res. pmid:17339605
Wu Y and Guo SW Suppression of IL-1beta-induced COX-2 expression by trichostatin A (TSA) in human endometrial stromal cells. 2007 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:17296257
Cao D et al. COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1. 2007 Am. J. Respir. Cell Mol. Biol. pmid:17395887
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Putnik J et al. The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60. 2007 Biochim. Biophys. Acta pmid:17980166
Kwon HS et al. Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression. 2006 Mar-Apr Biochim. Biophys. Acta pmid:16757381
Hansen KR et al. Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. 2006 Nucleic Acids Res. pmid:16407326
Fischer S et al. Histone acetylation dependent allelic expression imbalance of BAPX1 in patients with the oculo-auriculo-vertebral spectrum. 2006 Hum. Mol. Genet. pmid:16407370
Saunders LR and Verdin E Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors. 2006 Mol. Cancer Ther. pmid:17121924
Bieler A et al. Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520. 2006 Hum. Gene Ther. pmid:16409125
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Williams SA et al. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. 2006 EMBO J. pmid:16319923
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Zou B et al. Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. 2006 Gastroenterology pmid:17087954
Anderson I Deacetylase inhibitors aid recovery in muscular dystrophy. 2006 Lancet Neurol pmid:17089447
Kiefer J et al. Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells. 2006 Br. J. Nutr. pmid:17092367
Vinken M et al. Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes. 2006 Toxicol. Sci. pmid:16531468
Gastaldi T et al. Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and is regulated by DNA methylation and histone acetylation. 2006 Carcinogenesis pmid:16537559
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Suuronen T et al. Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia. 2006 Neurochem. Int. pmid:16797784
Wallace DM et al. Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina. 2006 Invest. Ophthalmol. Vis. Sci. pmid:16799012
Wischnewski F et al. Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells. 2006 Mol. Cancer Res. pmid:16687489
Yamada N et al. MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer. 2006 Int. J. Cancer pmid:16721789
Kim Y et al. Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. 2006 J. Steroid Biochem. Mol. Biol. pmid:16723222
Santander VS et al. Tubulin must be acetylated in order to form a complex with membrane Na(+),K (+)-ATPase and to inhibit its enzyme activity. 2006 Mol. Cell. Biochem. pmid:16733802
Kong Y et al. Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. 2006 Circulation pmid:16735673
Dannenberg LO et al. Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. 2006 Alcohol. Clin. Exp. Res. pmid:16737450
Cabrero JR et al. Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. 2006 Mol. Biol. Cell pmid:16738306
Vulcano F et al. HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers. 2006 Exp. Cell Res. pmid:16739251
Hirsch CL et al. Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells. 2006 Int. J. Cancer pmid:16094635
Scott SA et al. 5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation. 2006 Leuk. Res. pmid:16043219
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Clem BF and Clark BJ Association of the mSin3A-histone deacetylase 1/2 corepressor complex with the mouse steroidogenic acute regulatory protein gene. 2006 Mol. Endocrinol. pmid:16109738
Mai A et al. Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. 2006 J. Med. Chem. pmid:17004718
Yao J et al. NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. 2006 Pharmacol. Res. pmid:17005413
Inoue K et al. Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. 2006 Arterioscler. Thromb. Vasc. Biol. pmid:17008592
Baqir S and Smith LC Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells. 2006 Cloning Stem Cells pmid:17009896
Jung JW et al. Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells. 2006 Cancer Lett. pmid:16337085
Claus R et al. Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression. 2006 J. Leukoc. Biol. pmid:17000900
Kogai T et al. Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. 2006 Endocr. Relat. Cancer pmid:16954431
Tyson-Capper AJ et al. Characterization of cellular retinoid-binding proteins in human myometrium during pregnancy. 2006 Mol. Hum. Reprod. pmid:16959971
Chen J et al. Trichostatin A improves the anticancer activity of low concentrations of curcumin in human leukemia cells. 2006 Pharmazie pmid:16964716
Kim MY et al. A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. 2006 Proc. Natl. Acad. Sci. U.S.A. pmid:16924111
Mühlethaler-Mottet A et al. Histone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio. 2006 BMC Cancer pmid:16930472
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Fandy TE and Srivastava RK Trichostatin A sensitizes TRAIL-resistant myeloma cells by downregulation of the antiapoptotic Bcl-2 proteins. 2006 Cancer Chemother. Pharmacol. pmid:16435155
Deng G et al. Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. 2006 Int. J. Cancer pmid:16425274
Huang L et al. Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. 2006 Neurosci. Lett. pmid:16426753
Kim IA et al. Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53. 2006 Clin. Cancer Res. pmid:16467109
Osborn NK et al. Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia. 2006 Clin. Gastroenterol. Hepatol. pmid:16469682
Baraz L et al. Tumor suppressor p53 regulates heparanase gene expression. 2006 Oncogene pmid:16474844
Gialitakis M et al. Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. 2006 Nucleic Acids Res. pmid:16452299