Bence M et al. |
Transcriptional modulation of monoaminergic neurotransmission genes by the histone deacetylase inhibitor trichostatin A in neuroblastoma cells. |
2012 |
J Neural Transm |
pmid:21785940
|
Suh HS et al. |
Histone deacetylase inhibitors suppress the expression of inflammatory and innate immune response genes in human microglia and astrocytes. |
2010 |
J Neuroimmune Pharmacol |
pmid:20157787
|
Fleiss B et al. |
Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury. |
2012 |
J Neuroinflammation |
pmid:22512781
|
Noro R et al. |
The anticancer effect of histone deacetylase inhibitors and combination with the cytotoxic agents in lung cancer cells: biological analyses for future clinical application. |
2009 |
J Nippon Med Sch |
pmid:19305113
|
Por ED et al. |
Trichostatin A Inhibits Retinal Pigmented Epithelium Activation in an In Vitro Model of Proliferative Vitreoretinopathy. |
2016 |
J Ocul Pharmacol Ther |
pmid:27494828
|
Sun G et al. |
Insights into the lysine acetylproteome of human sperm. |
2014 |
J Proteomics |
pmid:25038526
|
Gavin DP et al. |
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. |
2009 |
J Psychiatr Res |
pmid:19187942
|
Gavin DP et al. |
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. |
2009 |
J Psychiatry Neurosci |
pmid:19448855
|
Albertus DL et al. |
AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma. |
2008 |
J Thorac Oncol |
pmid:18978557
|
Seo SK et al. |
Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. |
2011 |
J Thorac Oncol |
pmid:21642861
|
Selinger CI et al. |
Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer. |
2011 |
J Thorac Oncol |
pmid:21597389
|
Kakihana M et al. |
Induction of E-cadherin in lung cancer and interaction with growth suppression by histone deacetylase inhibition. |
2009 |
J Thorac Oncol |
pmid:20009910
|
Kimura T et al. |
Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300. |
2011 |
J Toxicol Sci |
pmid:21467744
|
Simões-Pires CA et al. |
Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS. |
2017 |
J Vis Exp |
pmid:28829415
|
Azuma R et al. |
Combinational Treatment of Trichostatin A and Vitamin C Improves the Efficiency of Cloning Mice by Somatic Cell Nuclear Transfer. |
2018 |
J Vis Exp |
pmid:29757287
|
Valapour M et al. |
Histone deacetylation inhibits IL4 gene expression in T cells. |
2002 |
J. Allergy Clin. Immunol. |
pmid:11842291
|
Su RC et al. |
Epigenetic regulation of established human type 1 versus type 2 cytokine responses. |
2008 |
J. Allergy Clin. Immunol. |
pmid:17980413
|
Milagre I et al. |
Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination. |
2010 |
J. Alzheimers Dis. |
pmid:20930312
|
Kudo K et al. |
Biosynthetic Origin of the Hydroxamic Acid Moiety of Trichostatin A: Identification of Unprecedented Enzymatic Machinery Involved in Hydroxylamine Transfer. |
2017 |
J. Am. Chem. Soc. |
pmid:28497964
|
Ren C et al. |
Peptide mass mapping of acetylated isoforms of histone H4 from mouse lymphosarcoma cells treated with histone deacetylase (HDACs) inhibitors. |
2005 |
J. Am. Soc. Mass Spectrom. |
pmid:16099169
|
Yoshikawa M et al. |
Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-beta1 in human renal epithelial cells. |
2007 |
J. Am. Soc. Nephrol. |
pmid:17135397
|
Yu Z et al. |
Histone deacetylases augment cytokine induction of the iNOS gene. |
2002 |
J. Am. Soc. Nephrol. |
pmid:12138131
|
Hou W et al. |
Hypoxia-induced deacetylation is required for tetraploid differentiation in response to testicular ischemia-reperfusion (IR) injury. |
2012 Nov-Dec |
J. Androl. |
pmid:22556385
|
Fenic I et al. |
In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
J. Androl. |
pmid:18046049
|
Fenic I et al. |
In vivo effects of histone-deacetylase inhibitor trichostatin-A on murine spermatogenesis. |
2004 Sep-Oct |
J. Androl. |
pmid:15292114
|
Shi LH et al. |
Trichostatin A and nuclear reprogramming of cloned rabbit embryos. |
2008 |
J. Anim. Sci. |
pmid:18245503
|
Ueda JY et al. |
JBIR-17, a novel trichostatin analog from Streptomyces sp. 26634. |
2009 |
J. Antibiot. |
pmid:19300468
|
Yoshida M et al. |
Structural specificity for biological activity of trichostatin A, a specific inhibitor of mammalian cell cycle with potent differentiation-inducing activity in Friend leukemia cells. |
1990 |
J. Antibiot. |
pmid:2211374
|
Otoguro K et al. |
Screening for new antitrichomonal substances of microbial origin and antitrichomonal activity of trichostatin A. |
1988 |
J. Antibiot. |
pmid:3372352
|
Takahashi I et al. |
Selective inhibition of IL-2 gene expression by trichostatin A, a potent inhibitor of mammalian histone deacetylase. |
1996 |
J. Antibiot. |
pmid:8682722
|
Komatsu Y and Hayashi H |
Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells. |
1998 |
J. Antibiot. |
pmid:9531994
|
Koguchi Y et al. |
Trichostatin A and herboxidiene up-regulate the gene expression of low density lipoprotein receptor. |
1997 |
J. Antibiot. |
pmid:9592573
|
Kim YB et al. |
Mechanism of cell cycle arrest caused by histone deacetylase inhibitors in human carcinoma cells. |
2000 |
J. Antibiot. |
pmid:11132966
|
Dupré-Aucouturier S et al. |
Trichostatin A, a histone deacetylase inhibitor, modulates unloaded-induced skeletal muscle atrophy. |
2015 |
J. Appl. Physiol. |
pmid:26112243
|
Jafari S et al. |
Epigenetic modification does not determine the time of POU5F1 transcription activation in cloned bovine embryos. |
2011 |
J. Assist. Reprod. Genet. |
pmid:22020531
|
Slattery EL et al. |
Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. |
2009 |
J. Assoc. Res. Otolaryngol. |
pmid:19340485
|
Azechi T et al. |
Trichostatin A, an HDAC class I/II inhibitor, promotes Pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase. |
2013 |
J. Atheroscler. Thromb. |
pmid:23518467
|
Okamoto H et al. |
Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). |
2006 |
J. Atheroscler. Thromb. |
pmid:16908950
|
Reilly CM et al. |
The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
2008 |
J. Autoimmun. |
pmid:18650065
|
Hildmann C et al. |
A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases. |
2004 |
J. Bacteriol. |
pmid:15060035
|
Maruoka H et al. |
Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons. |
2011 |
J. Biochem. |
pmid:21908547
|
Yamamoto I et al. |
Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate. |
1996 |
J. Biochem. |
pmid:8827437
|
Zhao W et al. |
The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island. |
2005 |
J. Biochem. |
pmid:15809347
|
Kook SH et al. |
Epstein-Barr virus-infected Akata cells are sensitive to histone deacetylase inhibitor TSA-provoked apoptosis. |
2005 |
J. Biochem. Mol. Biol. |
pmid:16336792
|
Zhang Y and Zhang B |
Trichostatin A, an Inhibitor of Histone Deacetylase, Inhibits the Viability and Invasiveness of Hypoxic Rheumatoid Arthritis Fibroblast-Like Synoviocytes via PI3K/Akt Signaling. |
2016 |
J. Biochem. Mol. Toxicol. |
pmid:26509796
|
Jin B and Ryu DY |
Regulation of CYP1A2 by histone deacetylase inhibitors in mouse hepatocytes. |
2004 |
J. Biochem. Mol. Toxicol. |
pmid:15252868
|
Henderson C et al. |
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). |
2003 |
J. Biol. Chem. |
pmid:12556448
|
Sanyal S et al. |
Differential regulation of the orphan nuclear receptor small heterodimer partner (SHP) gene promoter by orphan nuclear receptor ERR isoforms. |
2002 |
J. Biol. Chem. |
pmid:11705994
|
Galasinski SC et al. |
Global regulation of post-translational modifications on core histones. |
2002 |
J. Biol. Chem. |
pmid:11709551
|
Yin L et al. |
Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. |
2001 |
J. Biol. Chem. |
pmid:11572859
|
Liou JS et al. |
Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species. |
2000 |
J. Biol. Chem. |
pmid:10967125
|
Stimson KM and Vertino PM |
Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. |
2002 |
J. Biol. Chem. |
pmid:11733524
|
Kurtev V et al. |
Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases. |
2004 |
J. Biol. Chem. |
pmid:15140878
|
Klampfer L et al. |
Requirement of histone deacetylase activity for signaling by STAT1. |
2004 |
J. Biol. Chem. |
pmid:15123634
|
Fu M et al. |
The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity. |
2004 |
J. Biol. Chem. |
pmid:15123687
|
Rigamonti D et al. |
Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators. |
2007 |
J. Biol. Chem. |
pmid:17565993
|
Roy S and Tenniswood M |
Site-specific acetylation of p53 directs selective transcription complex assembly. |
2007 |
J. Biol. Chem. |
pmid:17121856
|
Kuno A et al. |
Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein. |
2013 |
J. Biol. Chem. |
pmid:23297412
|
Gusterson RJ et al. |
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity. |
2003 |
J. Biol. Chem. |
pmid:12477714
|
Phiel CJ et al. |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. |
2001 |
J. Biol. Chem. |
pmid:11473107
|
Jacob AL et al. |
Acetylation of steroidogenic factor 1 protein regulates its transcriptional activity and recruits the coactivator GCN5. |
2001 |
J. Biol. Chem. |
pmid:11479297
|
Gregory RI et al. |
Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells. |
2002 |
J. Biol. Chem. |
pmid:11821379
|
Lim Y et al. |
Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts. |
2002 |
J. Biol. Chem. |
pmid:11821402
|
Wilson MA et al. |
The histone deacetylase inhibitor trichostatin A blocks progesterone receptor-mediated transactivation of the mouse mammary tumor virus promoter in vivo. |
2002 |
J. Biol. Chem. |
pmid:11821430
|
Zhang L et al. |
Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts. |
2012 |
J. Biol. Chem. |
pmid:23024362
|
Brush MH et al. |
Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases. |
2004 |
J. Biol. Chem. |
pmid:14670976
|
Hattori N et al. |
Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. |
2004 |
J. Biol. Chem. |
pmid:14761969
|
Horion J et al. |
Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha. |
2007 |
J. Biol. Chem. |
pmid:17409387
|
Christian M et al. |
Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140. |
2004 |
J. Biol. Chem. |
pmid:14736873
|
Bu Y and Gelman IH |
v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. |
2007 |
J. Biol. Chem. |
pmid:17626016
|
Park SH et al. |
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells. |
2002 |
J. Biol. Chem. |
pmid:11744689
|
Singal R et al. |
Methylation of promoter proximal-transcribed sequences of an embryonic globin gene inhibits transcription in primary erythroid cells and promotes formation of a cell type-specific methyl cytosine binding complex. |
2002 |
J. Biol. Chem. |
pmid:11684679
|
Ammanamanchi S et al. |
Acetylated sp3 is a transcriptional activator. |
2003 |
J. Biol. Chem. |
pmid:12837748
|
Wang J et al. |
Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. |
2007 |
J. Biol. Chem. |
pmid:17675290
|
Sarg B et al. |
Histone H4 hyperacetylation precludes histone H4 lysine 20 trimethylation. |
2004 |
J. Biol. Chem. |
pmid:15456746
|
Hishiki T et al. |
BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3. |
2007 |
J. Biol. Chem. |
pmid:17644518
|
Lin AC et al. |
The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors. |
2004 |
J. Biol. Chem. |
pmid:15507435
|
Diamond SE and Gutierrez-Hartmann A |
The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. |
2000 |
J. Biol. Chem. |
pmid:10921928
|
Spallotta F et al. |
A nitric oxide-dependent cross-talk between class I and III histone deacetylases accelerates skin repair. |
2013 |
J. Biol. Chem. |
pmid:23463510
|
Mogal AP et al. |
Haploinsufficient prostate tumor suppression by Nkx3.1: a role for chromatin accessibility in dosage-sensitive gene regulation. |
2007 |
J. Biol. Chem. |
pmid:17602165
|
Wong CY et al. |
Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells. |
2011 |
J. Biol. Chem. |
pmid:21636851
|
Su M et al. |
Recruitment of nuclear factor Y to the inverted CCAAT element (ICE) by c-Jun and E1A stimulates basal transcription of the bone sialoprotein gene in osteosarcoma cells. |
2005 |
J. Biol. Chem. |
pmid:16087680
|
Milutinovic S et al. |
Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification. |
2002 |
J. Biol. Chem. |
pmid:11929879
|
McCool KW et al. |
The role of histone acetylation in regulating early gene expression patterns during early embryonic stem cell differentiation. |
2007 |
J. Biol. Chem. |
pmid:17204470
|
Wen J et al. |
Tal1/SCL binding to pericentromeric DNA represses transcription. |
2005 |
J. Biol. Chem. |
pmid:15677454
|
Waterborg JH |
Dynamics of histone acetylation in Chlamydomonas reinhardtii. |
1998 |
J. Biol. Chem. |
pmid:9765294
|
Verdel A and Khochbin S |
Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers. |
1999 |
J. Biol. Chem. |
pmid:9891014
|
Simboeck E et al. |
A phosphorylation switch regulates the transcriptional activation of cell cycle regulator p21 by histone deacetylase inhibitors. |
2010 |
J. Biol. Chem. |
pmid:20952396
|
Yamaguchi K et al. |
Histone deacetylase inhibitors suppress the induction of c-Jun and its target genes including COX-2. |
2005 |
J. Biol. Chem. |
pmid:15994313
|
Marks J et al. |
Two functionally divergent p53-responsive elements in the rat bradykinin B2 receptor promoter. |
2003 |
J. Biol. Chem. |
pmid:12791684
|
Vanden Berghe W et al. |
The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. |
1999 |
J. Biol. Chem. |
pmid:10542243
|
Asthana J et al. |
Inhibition of HDAC6 deacetylase activity increases its binding with microtubules and suppresses microtubule dynamic instability in MCF-7 cells. |
2013 |
J. Biol. Chem. |
pmid:23798680
|
Liao M et al. |
Coactivator function of positive cofactor 4 (PC4) in Sp1-directed luteinizing hormone receptor (LHR) gene transcription. |
2011 |
J. Biol. Chem. |
pmid:21193408
|
Liu CJ et al. |
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. |
2004 |
J. Biol. Chem. |
pmid:15337766
|
Muralidhar SA et al. |
Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells. |
2011 |
J. Biol. Chem. |
pmid:21078662
|
Hayakawa F et al. |
Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. |
2008 |
J. Biol. Chem. |
pmid:18621739
|
Hichino A et al. |
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells. |
2017 |
J. Biol. Chem. |
pmid:28057758
|
Johnson CA et al. |
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. |
2001 |
J. Biol. Chem. |
pmid:11136718
|
Yoshioka H et al. |
Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
|
Banchio C et al. |
Role of histone deacetylase in the expression of CTP:phosphocholine cytidylyltransferase alpha. |
2006 |
J. Biol. Chem. |
pmid:16484221
|