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2009 |
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LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer. |
2009 |
Oncogene |
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HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer. |
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Oncogene |
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Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications. |
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PLoS ONE |
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[Nucleosome positioning within neomycinphosphotransferase gene (NPTII) on yeast plasmid in repressed and active state]. |
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2008 Nov-Dec |
Nutrition |
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In vivo application of histone deacetylase inhibitor trichostatin-a impairs murine male meiosis. |
2008 Mar-Apr |
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To the nucleolar density and size in apoptotic human leukemic myeloblasts produced in vitro by Trichostatin A. |
2008 Jul-Sep |
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The effect of histone deacetylase inhibitor trichostatin A (TSA) on the incorporation of 32P (Pi) and 3H-palmitic acid into the phospholipids of Tetrahymena. |
2008 Jan-Feb |
Cell Biochem. Funct. |
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Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. |
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Biochemistry |
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Tsitologiia |
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Mol. Vis. |
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Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. |
2008 |
Cancer Immunol. Immunother. |
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Breast Cancer Res. Treat. |
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Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. |
2008 |
Oncogene |
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DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines. |
2008 |
Prostate |
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Restoration of CREB function ameliorates cisplatin cytotoxicity in renal tubular cells. |
2008 |
Am. J. Physiol. Renal Physiol. |
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p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. |
2008 |
Oncogene |
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The spatial relationship between heterochromatin protein 1 alpha and histone modifications during mouse oocyte meiosis. |
2008 |
Cell Cycle |
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The effects of trichostatin A on mRNA expression of chromatin structure-, DNA methylation-, and development-related genes in cloned mouse blastocysts. |
2008 |
Cloning Stem Cells |
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Spatial distribution of histone methylation during MHC class II expression. |
2008 |
Mol. Immunol. |
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Eur J Med Chem |
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Acetylation of the Entamoeba histone H4 N-terminal domain is influenced by short-chain fatty acids that enter trophozoites in a pH-dependent manner. |
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Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virus-infected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors. |
2008 |
J. Virol. |
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2008 |
Genomics |
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Modulation of immunoglobulin gene conversion frequency and distribution by the histone deacetylase HDAC2 in chicken DT40. |
2008 |
Genes Cells |
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ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. |
2008 |
J. Cancer Res. Clin. Oncol. |
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Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. |
2008 |
Dev. Dyn. |
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Upregulation of annexin A1 expression by butyrate in human colon adenocarcinoma cells: role of p53, NF-Y, and p38 mitogen-activated protein kinase. |
2008 |
Mol. Cell. Biol. |
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Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera. |
2008 |
Cancer Sci. |
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Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility. |
2008 |
Am. J. Obstet. Gynecol. |
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Genes Dev. |
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2008 |
Oncogene |
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Mol. Cancer Ther. |
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2008 |
Chem Soc Rev |
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CCAAT box is required for the induction of human thrombospondin-1 gene by trichostatin A. |
2008 |
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Unlocking repression of the human luteinizing hormone receptor gene by trichostatin A-induced cell-specific phosphatase release. |
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Effect of histone deacetylase inhibitor on proliferation of biliary tract cancer cell lines. |
2008 |
World J. Gastroenterol. |
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Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells. |
2008 |
Rheumatology (Oxford) |
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Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. |
2008 |
Neuro-oncology |
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Induction of ID1 expression and apoptosis by the histone deacetylase inhibitor (trichostatin A) in human acute myeloid leukaemic cells. |
2008 |
Cell Prolif. |
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Epigenetic remodeling during arsenical-induced malignant transformation. |
2008 |
Carcinogenesis |
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2008 |
Int. J. Cancer |
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Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. |
2008 |
Microbiology (Reading, Engl.) |
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Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells. |
2008 |
Oncol. Rep. |
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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. |
2008 |
Proc. Natl. Acad. Sci. U.S.A. |
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Modulation of transcription parameters in glucocorticoid receptor-mediated repression. |
2008 |
Mol. Cell. Endocrinol. |
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Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2. |
2008 |
Cancer Res. |
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Brain chromatin remodeling: a novel mechanism of alcoholism. |
2008 |
J. Neurosci. |
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Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. |
2008 |
Angiogenesis |
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Differential effects of hydroxamate histone deacetylase inhibitors on cellular functionality and gap junctions in primary cultures of mitogen-stimulated hepatocytes. |
2008 |
Toxicol. Lett. |
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[Effect of trichostatin A on proliferation and interleukin-2 expression of mouse T cells in mixed lymphocyte culture]. |
2008 |
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Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors. |
2008 |
Pulm Pharmacol Ther |
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HDAC inhibitors effectively induce cell type-specific differentiation in human glioblastoma cell lines of different origin. |
2008 |
Int. J. Oncol. |
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Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice. |
2008 |
Mol. Cell. Neurosci. |
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Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy. |
2008 |
Bioorg. Med. Chem. |
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A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts. |
2008 |
Cell Cycle |
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Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR. |
2008 |
Breast Cancer Res. Treat. |
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Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice. |
2008 |
Radiat. Res. |
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Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6. |
2008 |
J. Med. Chem. |
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Spinal muscular atrophy: motoneurone or muscle disease? |
2008 |
Neuromuscul. Disord. |
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Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors. |
2008 |
Antimicrob. Agents Chemother. |
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Trichostatin A improves histone acetylation in bovine somatic cell nuclear transfer early embryos. |
2008 |
Cloning Stem Cells |
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Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells. |
2008 |
Mol. Cancer Res. |
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Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects. |
2008 |
Mol. Ther. |
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Array-based analysis of the effects of trichostatin A and CG-1521 on cell cycle and cell death in LNCaP prostate cancer cells. |
2008 |
Mol. Cancer Ther. |
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Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. |
2008 |
J. Biol. Chem. |
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The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. |
2008 |
J. Autoimmun. |
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Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation. |
2008 |
Exp. Cell Res. |
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Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. |
2008 |
J. Leukoc. Biol. |
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[Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro]. |
2008 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
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Gastric cancer cell lines induced by trichostatin A. |
2008 |
World J. Gastroenterol. |
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Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
2008 |
Int. J. Oncol. |
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Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A. |
2008 |
Oncol. Rep. |
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AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. |
2008 |
Development |
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Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. |
2008 |
J. Mol. Cell. Cardiol. |
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Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas. |
2008 |
Genes Genet. Syst. |
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Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A. |
2008 |
J. Biol. Chem. |
pmid:18801729
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Wu Y and Guo SW |
Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells. |
2008 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:17376583
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Jin B et al. |
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. |
2008 |
Hum. Mol. Genet. |
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Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. |
2008 |
Biochem. Biophys. Res. Commun. |
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Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells. |
2008 |
Int. J. Oncol. |
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Van Wagoner DR and Nattel S |
Insights into mechanisms linking cardiac hypertrophy and atrial fibrosis: evidence for a role of histone deacetylase in atrial fibrillation pathophysiology and therapy. |
2008 |
J. Mol. Cell. Cardiol. |
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